Background: Many patients undergo percutaneous coronary intervention (PCI) without the use of non-invasive stress testing prior to treatment. The aim of this study was to determine the potential added value of guiding revascularization by quantitative assessment of myocardial perfusion prior to intervention. Methods and Results: Thirty-three patients (10 females) with suspected or established CAD

A general framework for determining fundamental bounds in nanophotonics is introduced in this paper. The theory is based on convex optimization of dual problems constructed from operators generated by electromagnetic integral equations. The optimized variable is a contrast current defined within a prescribed region of a given material constitutive relations. Two power conservation constraints anal

Populärvetenskaplig sammanfattningAluminium används för en stor mängd produkter, allt från hus och i fordon till såvardagliga produkter som aluminiumburkar. Det breda användningsområdet beror på aluminiumets höga hållfasthet, lätta vikt och dess goda korrosionsmotståndighet. Korrosionsmotståndet beror på att när aluminium exponeras för luft bildas ett aluminiumoxidskikt på ytan, vilket skyddar aluAbstractIn this thesis, the electrochemical deposition process of Sn into ordered nanoporous anodic aluminium oxide (NP-AAO) have been studied. The deposition process was studied in situ using the X-ray techniques: X-ray diffraction (XRD), Grazing incidence Transmission Small-Angle X-ray Scattering (GTSAXS), X-ray Fluorescence (XRF) and X-ray Absorption Near Edge Structure (XANES) and ex situ usin

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Systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) are two autoimmune diseases that can occur together or separately. Insights into the pathogenesis have revealed similarities, such as development of autoantibodies targeting subcellular antigens as well as a shared increased risk of cardiovascular morbidity, potentially due to mutual pathologic mechanisms. In this review, we wi

OBJECTIVES: To investigate associations between a high genetic disease risk and disease severity in patients with systemic lupus erythematosus (SLE).METHODS: Patients with SLE (n=1001, discovery cohort and n=5524, replication cohort) and healthy controls (n=2802 and n=9859) were genotyped using a 200K Immunochip single nucleotide polymorphism array. A genetic risk score (GRS) was assigned to each

A large number of observational epidemiological studies have reported generally positive associations between circulating mass and activity levels of lipoprotein-associated phospholipase A2 (Lp-PLA2) and the risk of cardiovascular diseases. Few studies have been large enough to provide reliable estimates in different circumstances, such as in different subgroups (e.g., by age group, sex, or smokin

Objective: To determine the frequency, clinical characteristics, associations, and outcomes of different types of peripheral nervous system (PNS) disease in a multiethnic/multiracial, prospective inception cohort of systemic lupus erythematosus (SLE) patients. Methods: Patients were evaluated annually for 19 neuropsychiatric (NP) events including 7 types of PNS disease. SLE disease activity, organ

The immunocytochemical distribution of substance P (SP), gastrin releasing peptide (GRP), vasoactive intestinal polypeptide (VIP), peptide histidine isoleucine (PHI), and neuropeptide Y (NPY) was studied in the ovary and the Fallopian tube (oviduct) of rats, guinea-pigs, cows, pigs and humans. Generally, the nerve supply was better developed in the oviduct than in the ovary. GRP fibers were most s

Lindström & Alerstam (1992Am. Nat.140,477–491) presented a model that predicts optimal departure fuel loads as a function of the rate of fuel deposition in time-minimizing migrants. The basis of the model is that the coverable distance per unit of fuel deposited, diminishes with increasing fuel load. This is an effect of the increasing flight costs associated with increasing body mass. Lindstr

Paper 1: “The Effects of Board Independence on Busy Directors and Firm Value: Evidence from Regulatory Changes in Sweden.” I use an exogenous change to the rules of corporate governance for Swedish firms in 2005 to identify the causal effects of changes in board structure on firm value. The new rules require there to be at least 50 percent independent directors on the boards of large firms. This o