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Mechanics and Ca(2+)-sensitivity of human detrusor muscle bundles studied in vitro

Mechanical properties of isolated smooth muscle strips from human urinary bladder were investigated in vitro. Bladder tissue was obtained from tumour-free wall regions of bladders from male patients undergoing cystectomy for bladder carcinoma. In intact muscle strips, activated with high-K+ solution, half-maximal force occurred at about 0.9 mM extracellular [Ca2+]. The length-active force relation

Travel patterns and environmental effects now and in the future: implications of differences in energy consumption among socio-economic groups.

Travel patterns among different socio-economic groups in Sweden are investigated. It is shown that elderly persons, persons with low incomes and women in general do not travel extensively. Middle-aged persons, persons with high incomes and men travel much farther. Cars are the dominant transportation mode for all population groups. Aeroplanes are used mostly by high-income earners and men, while p

Unequal error protection for convolutional codes

In this correspondence, unequal error-correcting capabilities of convolutional codes are studied. For errors in the information symbols and code symbols, the free input- and output-distances, respectively, serve as '' unequal '' counterparts to the free distance. When communication takes place close to or above the channel capacity the error bursts tend to be long and the free distance is not any

Domain swapping as a molecular mechanism in amyloidosis

Popular Abstract in Swedish Som en blixt från klar himmel drabbas en ung, och till synes frisk person, av hjärnblödning. Denna stroke leder till demens och efterföljande nya blödningar leder slutligen till en för tidig död. Man har kunnat visa att denna sjukdom beror på att en variant av ett visst protein, cystatin C, tvinnar ihop sig till rep-liknande långa fibriller. Dessa fibriller ansamlas sedAmyloidosis is a group of diseases characterized by a change in protein conformation resulting in aggregation and tissue deposition of amyloid fibrils. One variant of cystatin C, L68Q cystatin C, is highly amyloidogenic and persons carrying the corresponding gene suffer from massive cerebral amyloidosis leading to brain hemorrhage and death. Amyloidogenic proteins like cystatin C and prion protein

Affinity analysis of lectin interaction with immobilized C- and O-gylcosides studied by surface plasmon resonance assay

A biosensor based on the surface plasmon resonance (SPR) principle was used for kinetic analysis of lectin interactions with different immobilized saccharide structures. A novel affinity ligands beta-D-glycopyranosylmethylamines derived from common D-aldohexoses linked to the carboxymethyl dextran layer of the SPR sensor surface served for interactions with a wide range of lectins. The method of p

Leaching of concrete : the leaching process : extrapolation of deterioration : effect on the structural stability

The leaching process when water attacks concrete, and the effect of leaching on the strength and durability of a concrete structure, is analysed theoretically. Technique for prediction of the future leaching and structural stability is outlined. The analysis is to a certain extent supported by data from literature. The leaching process is divided in five different types: 1: Pure surface leaching 2

Randomized radio stereometric study comparing osteogenic protein-1 (BMP-7) and autograft bone in human noninstrumented posterolateral lumbar fusion - 2002 Volvo Award in Clinical Studies

Study Design. Randomized efficacy trial comparing two types of noninstrumented posterolateral fusion between L5 and S1 in patients with L5 spondylolysis and vertebral slip less than 50%, as evaluated by radiosterometric analysis. Objective. To determine whether osteogenic protein-1 (BMP-7) in the OP-1 Implant yields better stabilizing bony fusion than autograft bone. Summary of Background Data. An

Mechanical deformation of compressible chromatographic columns

A one-dimensional model of mechanical deformation of compressible chromatography columns is presented. The model is based on linear elasticity and continuum mechanics and is compared to a more complete two-dimensional model and one-dimensional porosity profiles measured by NMR imaging methods. The model provides a quantitative description of compression and the effects of wall support during scale

Transvaginal gray-scale and Doppler ultrasound examinations of the uterus and ovaries in healthy postmenopausal women

The aim of this study was to elicit reference data representative of normal findings at transvaginal gray-scale and Doppler ultrasound examination of the uterus and ovaries in postmenopausal women. A total of 144 asymptomatic postmenopausal women with normal findings at clinical gynecological examination were included in the study. They underwent transvaginal sonography including Doppler measureme

Danskjävlar och svenskesvin

Artikel om etnologiforskningens syn på föreställningen om Danmark och Sverige i de respektive grannländerna.

The influence of propofol on vomiting induced by apomorphine

It has been proposed that propofol has antiemetic effects even in nonsedative doses. The aim of this study was to investigate whether propofol influences vomiting induced by the dopamine agonist apomorphine. Ten healthy male volunteers received apomorphine infusion (1 mg/min) until vomiting was induced on four different occasions in a randomized order: a) during propofol infusion (2.4 +/- 0.7 mg.k

An Economic Analysis of Marriage and Divorce

The first chapter develops a theoretical model of marriage and divorce. The model has two periods and assumes Pareto efficient time allocations. There is a risk of divorce in the second period, which is modeled as exogenously given. The second chapter utilizes the model developed in the previous chapter to analyze the equality between married men and women. Equality is defined as the spouses' rel

No relationship between epidural fibrosis and sciatica in the lumbar postdiscectomy syndrome. A study with contrast-enhanced magnetic resonance imaging in symptomatic and asymptomatic patients

STUDY DESIGN. Symptomatic patients were retrospectively analyzed and compared with a control group from an ongoing prospective and consecutive study. OBJECTIVES. To determine the presence and extent of epidural fibrosis in patients with and without recurrent sciatic pain after previous lumbar discectomy, contrast-enhanced magnetic resonance images were evaluated and correlated with surgical findin

Chromosomal locations of six barley genes encoding enzymes of chlorophyll and heme biosynthesis and the sequence of the ferrochelatase gene identify two regulatory genes

The chromosomal location of six barley genes was determined by Southern blot experiments using wheat strains which contained the short or long arm from one of the seven barley chromosomes. The genes analysed encode enzymes that are required for chlorophyll and heme synthesis. Glutamyl-tRNAGlu synthetase, glutamate 1-semialdehyde 2,1-aminotransferase and glutamyl-tRNAGlu reductase are common to bot

The Hardman index in patients operated on for ruptured abdominal aortic aneurysm: A systematic review.

Background. The aims of the present study were to (1) analyze preoperative predictors for outcome suggested by Hardman and surgical mortality after open repair and endovascular repair (EVAR) of ruptured abdominal aortic aneurysms (rAAA), and (2) further evaluate the Hardman index in a systematic review. Methods. Patients operated on for rAAA during a 5-year period between 2000 and 2004 were scored