Sökresultat

Filtyp

Din sökning på "*" gav 529858 sökträffar

Post-Islamism and fields of contention after the Arab Spring : feminism, Salafism and the revolutionary youth

In the aftermath of the Arab Spring, conflicts in Egypt and Tunisia over the authority to rule and the role of religion in society raised questions about these societies’ capacity for reconciling differences. In retrospect, the conflicts also raise questions about the theoretical tools used to analyse regional developments. In particular, the ‘post-Islamism’ thesis has significantly changed the de

Orphan drug policies and use in pediatric nephrology

Orphan drugs designed to treat rare diseases are often overpriced per patient. Novel treatments are sometimes even more expensive for patients with ultra-rare diseases, in part due to the limited number of patients. Pharmaceutical companies that develop a patented life-saving drug are in a position to charge a very high price, which, at best, may enable these companies to further develop drugs for

Changes in prevalence of obesity and high waist circumference over four years across European regions : the European male ageing study (EMAS)

Diversity in lifestyles and socioeconomic status among European populations, and recent socio-political and economic changes in transitional countries, may affect changes in adiposity. We aimed to determine whether change in the prevalence of obesity varies between the socio-politically transitional North-East European (Łódź, Poland; Szeged, Hungary; Tartu, Estonia), and the non-transitional Medit

Protein-dependent membrane interaction of a partially disordered protein complex with oleic acid : Implications for cancer lipidomics

Bovine α-lactalbumin (BLA) forms cytotoxic complexes with oleic acid (OA) that perturbs tumor cell membranes, but molecular determinants of these membrane-interactions remain poorly understood. Here, we aim to obtain molecular insights into the interaction of BLA/BLA-OA complex with model membranes. We characterized the folding state of BLA-OA complex using tryptophan fluorescence and resolved res

Development of a moisture safe connection for stud walls

Moisture penetration around windows and doors is a problem with serious consequences for stud walls and is a common problem regardless of facade systems. The problem has received considerable focus in recent times, as buildings using ETICS (External thermal insulation composite systems) on stud walls have been damaged by penetrating water. In the present paper a robust moisture safe prefabricated

Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers

Triple-negative (TN) breast cancers (ER â ' PR â ' HER2 â ') are highly metastatic and associated with poor prognosis. Within this subtype, invasive, stroma-rich tumours with infiltration of inflammatory cells are even more aggressive. The effect of myeloid cells on reactive stroma formation in TN breast cancer is largely unknown. Here, we show that primary human monocytes have a survival advantag

Shaping Information Infrastructure Evolution : Governmental Claims of Architectural Control Points

Payments are central for society. Historically, it involved two parties exchanging goods and services for money. Today, payments, with increasing frequency, consist of digital representations of money that are transferred through globally intertwined network. Payments involve many parties such as payers, payment services providers, banks, central banks, telecom operators, mobile handset manufactur

Modelling time-to-cracking in brick masonry with corroding bed joint reinforcement

Clay brick facades often include bed joint reinforcement, especially over windows and other openings in the façade, which may corrode due to degradation from climatic exposure. Removal of corroded bed joint reinforcement from such facades is an invasive and costly measure. Heavily damaged reinforcement must be removed for either structural, durability or aesthetic reasons. Parts of the bed joint r

Rehabilitation of masonry facades damaged by reinforcement corrosion

This paper presents results from a project dealing with rehabilitation of clay brick facades damaged by reinforcement corrosion. Based on laboratory tests and results from pilot projects, practical recommendations for appropriate removal of bed joint reinforcement and repair of joints are issued for facility owners, contractors and designers.

Green and blue water demand from large-scale land acquisitions in Africa

In the last decade, more than 22 million ha of land have been contracted to large-scale land acquisitions in Africa, leading to increased pressures, competition, and conflicts over freshwater resources. Currently, 3% of contracted land is in production, for which we model site-specific water demands to indicate where freshwater appropriation might pose high socioenvironmental challenges. We use th

Knowledge and utilization of sexual and reproductive healthcare services among Thai immigrant women in Sweden

Background: Migration from Thailand to Sweden has increased threefold over the last 10 years. Today Thailand is one of the most common countries of origin among immigrants in Sweden. Since the year 2000, new HIV cases are also more prevalent among Thai immigrants compared to other immigrant nationalities in Sweden. The purpose of this study was to investigate the association between knowledge and

Venous thromboembolism with special focus on genetic and potential acquired risk factors

Venous thromboembolism (VTE) is a relatively common cause of morbidity and mortality. It has an annual incidence of around 0.1- 0.3%. It is a multifactorial disease with many known risk factors, both transient and persistent. Among these, several genetic risk factors have been described. The most common genetic risk factor, factor V Leiden mutation in heterozygote form, is found in 5-8% of the Cau

Light use efficiency of peatlands: Variability and suitability for modeling ecosystem production

Peatland net ecosystem production is a key variable to assess changes in the functional role of peatlands in the global carbon cycle. Light use efficiency (LUE) models in combination with satellite data have been used to estimate production for most major ecosystems, but peatlands have been largely ignored. The objectives of this study were: 1) to examine how the LUE parameter epsilon, ε (the amou

The Revised Sunspot Record in Comparison to Cosmogenic Radionuclide-Based Solar Activity Reconstructions

Recent revisions in the sunspot records illustrate the challenges related to obtaining a 400-year-long observational record of past solar-activity changes. Cosmogenic radionuclides offer the possibility of obtaining an alternative and completely independent record of solar variability. Here, we illustrate that these records offer great potential for quantitative solar-activity reconstructions far

Eliminating hydrolytic activity without affecting the transglycosylation of a GH1 β-glucosidase

Unveiling the determinants for transferase and hydrolase activity in glycoside hydrolases would allow using their vast diversity for creating novel transglycosylases, thereby unlocking an extensive toolbox for carbohydrate chemists. Three different amino acid substitutions at position 220 of a GH1 β-glucosidase from Thermotoga neapolitana caused an increase of the ratio of transglycosylation to hy

Assessment of diesel-contaminated domestic wastewater treated by constructed wetlands for irrigation of chillies grown in a greenhouse

In order to avoid environmental pollution and eliminate the need for using fertiliser, this study assessed for the first time the optimum performance of mature (in operation since 2011) vertical flow constructed wetlands in treating domestic wastewater (with and without hydrocarbon) and the subsequent recycling of the outflow to irrigate chillies (De Cayenne; Capsicum annuum (Linnaeus) Longum Grou