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Family adaptation in relation to a family member's stay in ICU.

OBJECTIVES: To describe and interpret the family adaptation during the ICU hospitalisation and up to 18 months after discharge. RESEARCH METHODOLOGY/DESIGN: A qualitative design was chosen. MAIN OUTCOME MEASURES: Individual and family interviews with eight families including 31 family members. A hermeneutical analysis was performed and paradigm cases were constructed. RESULTS: The result is presen

Interleukin-6 Is Elevated in the Cerebrospinal Fluid of Suicide Attempters and Related to Symptom Severity.

BACKGROUND: Depressive disorders are associated with immune system alterations that can be detected in the blood. Cytokine concentrations in cerebrospinal fluid (CSF) and their relationship to aspects of suicidality have previously not been investigated. METHODS: We measured interleukin-1beta, interleukin-6 (IL-6), interleukin-8, and tumor necrosis factor-alpha (TNF-alpha) in CSF and plasma of sui

Structural Basis for c-KIT Inhibition by the Suppressor of Cytokine Signaling 6 (SOCS6) Ubiquitin Ligase

The c-KIT receptor tyrosine kinase mediates the cellular response to stem cell factor (SCF). Whereas c-KIT activity is important for the proliferation of hematopoietic cells, melanocytes and germ cells, uncontrolled c-KIT activity contributes to the growth of diverse human tumors. Suppressor of cytokine signaling 6 (SOCS6) is a member of the SOCS family of E3 ubiquitin ligases that can interact wi

Ultrasound dating at 12-14 or 15-20 weeks of gestation? A prospective cross-validation of established dating formulae in a population of in-vitro fertilized pregnancies randomized to early or late dating scan

Objectives To determine the accuracy of established ultrasound dating formulae when used at 12-14 and 15-20 gestational weeks. Methods A total of 363 singleton pregnancies conceived after in-vitro fertilization (IVF) and randomized to a dating scan at 12-14 or 15-20 gestational weeks were studied. 'True' gestational age was calculated on the basis of the day of oocyte retrieval and was compared to

Ta plats eller få plats? : Studier av marginaliserade människors förändrade vardagsliv

Syftet är att studera och analysera processer vars mål är att förändra vardagen för två marginaliserade grupper, så att de i större utsträckning blir delaktiga i samhället. De två undersökta grupperna är manliga unga narkomaner och äldre utvecklingsstörda. Avhandlingen består av tre geografiska perspektiv: 1) det tidsgeografiska synsättet, 2) känslan för platsen och 3) socialgeografiska teorier omThe aim is to study and analyse processes intended to change the daily lives of two marginalised groups and enable them to participate to a greater extent in the community. The two marginalised groups are young male drug addicts and older intellectually disabled. The thesis is permeated by three geographic perspectives: 1) the time-geographic approach, 2) sense of place and 3) social-geographic th

Generation of gut-homing T cells and their localization to the small intestinal mucosa.

The intestinal mucosa represents the largest body surface toward the external environment and harbors numerous T lymphocytes that take up resident within the intestinal epithelium or in the underlying lamina propria (LP). The intraepithelial lymphocytes include subsets of 'unconventional' T cells with unclear ontogeny and reactivity that localize to this site independently of antigen-specific acti

High-resolution analysis of ambulatory electrocardiograms to detect possible mechanisms of premature ventricular beats

For generations of electrocardiogram (ECG) analysis, the presence of premature ventricular beats (PVBs) has been characterized as a common event in the ECG without regard to the mechanism which has caused the PVB in the first place. At best, the coupling interval with the preceding sinus beat may be noted. This viewpoint persisted throughout the era of automated ECG analysis, as well as influencin

Effects on the ciliated epithelium of protein D-producing and -nonproducing nontypeable Haemophilus influenzae in nasopharyngeal tissue cultures

A pair of isogenic, nontypeable Haemophilus influenzae strains, one expressing protein D and the other protein D-negative, was compared in their ability to cause damage in a human nasopharyngeal tissue culture model. Damage was assessed by measuring the ciliary beat frequency (CBF) of tissue specimens at 12 h intervals. Cultures inoculated with H. influenzae manifested a decrease in CBF beginning

Do antitrust laws facilitate collusion? Experimental evidence on costly communication in duopolies

Bertrand supergames with non- binding communication are used to study price formation and stability of collusive agreements on experimental duopoly markets. The experimental design consists of three treatments with different costs of communication: zero- cost, low- cost and high- cost. Prices are found to be significantly higher when communication is costly. Moreover, costly communication decrease

Tracing the Galactic Thick Disk to Solar Metallicities

We show that the Galactic thick disk reaches at least solar metallicities and that it experienced strong chemical enrichment during a period of ~3 Gyr, ending around 8-9 Gyr ago. This finding puts further constraints on the relation and interface between the thin and thick disks and their formation processes. Our results are based on a detailed elemental abundance analysis of 261 kinematically sel

Experiences from the implementation of a urine separation system: Goals, planning, reality

Over the last decade it has been ever increasing interest in developing alternative sanitary systems, which would be more sustainable than a conventional one is. In Sweden urine separation has been considered a promising approach towards increasing recycling of wastewater nutrients. Full scale trials are carried out and examined. This paper presents a study on implementation of urine separation sy

Wildfires in NW Patagonia: long-term effects on a Nothofagus forest soil

In NW Patagonia, Argentina, poor regeneration after fires of Nothofagus pumilio (Poepp. and Endl.) Krasser forests located in drier environments has been attributed to probable edaphic changes. We studied the long-term effects of wildfire on the mineralogical, physical, chemical and biological properties of a soil developed from volcanic-ashes under N. pumilio forests. Soils from six small patches

Gamma-ray Spectroscopy of Excited States in 61Zn

The Zn-61(30)31 isotope has been produced at the Oak Ridge National Laboratory in the fusion-evaporation reaction Ca-40(Mg-24, 2pn)Zn-61 at 104 MeV. The experimental set-up allowed gamma-rays to be detected in the CLARION Ge detector array in coincidence with the detection of recoiling nuclei in the focal plane at the end of the recoil mass spectrometer. This provides a unique identification of ga

Fetal gender and gestational-age-related incidence of pre-eclampsia.

Background. Male fetal gender is associated with an overall increased risk of pre-eclampsia. However, it was recently shown that the male: female birth ratio was decreased in pre-eclampsia associated with preterm delivery. The reason for this discrepancy is not known. Objective. To investigate whether the fetal and newborn gender is associated with the incidence of antenatal maternal pregnancy com