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Low to moderate lifetime alcohol consumption is associated with less advanced stages of fibrosis in non-alcoholic fatty liver disease

Background and aim: Moderate alcohol consumption has been associated with a lower risk of disease severity in non-alcoholic fatty liver disease (NAFLD). It is unclear if this reflects current or lifetime drinking, or can be attributed to confounders such as diet and exercise. We evaluated the impact of lifetime alcohol consumption on fibrosis severity in NAFLD. Methods: We prospectively enrolled 1

Impact of penalizing factor in a block-sequential regularized expectation maximization reconstruction algorithm for 18 F-fluorocholine PET-CT regarding image quality and interpretation

Background: Recently, the block-sequential regularized expectation maximization (BSREM) reconstruction algorithm was commercially introduced (Q.Clear, GE Healthcare, Milwaukee, WI, USA). However, the combination of noise-penalizing factor (β), acquisition time, and administered activity for optimal image quality has not been established for 18 F-fluorocholine (FCH). The aim was to compare image

Transmission dynamics study of tuberculosis isolates with whole genome sequencing in southern Sweden

Epidemiological contact tracing complemented with genotyping of clinical Mycobacterium tuberculosis isolates is important for understanding disease transmission. In Sweden, tuberculosis (TB) is mostly reported in migrant and homeless where epidemiologic contact tracing could pose a problem. This study compared epidemiologic linking with genotyping in a low burden country. Mycobacterium tuberculosi

The combined effect of termite bioturbation and water erosion on soil nutrient stocks along a tropical forest catena in Ghana

In the tropical moist semi-deciduous forests of West Africa, soil catenas with extremely gravel-rich soil horizons at the summits and upper slopes and largely gravel-free profiles at the lower slope are common. Previous investigations have suggested that these gravel layers are the result of macro-invertebrates mining of fine-grained soil material from the subsoil leaving behind the gravel, to bu

Use of 10 Be isotope to predict landscape development in the source area of the Yellow River (SAYR), northeastern Qinghai-Tibet Plateau

The magnitude of soil and sediment erosion and accumulation processes can profoundly affect landscape development and hamper efficient management of natural resources. Consequently, estimating the rates and causes of these processes is essential, particularly in remote regions, for prediction of changes in landform and river evolution and protection of local ecosystem. We here present the results

On the Combustion Characteristics of Closely-Coupled LD Diesel Injection Strategies

Multiple-pilot injection strategies with both moderate and short time separations (dwells) are investigated in a light-duty diesel engine. Both conventional and optical engine experiments are performed. By implementing triple-pilot injection strategies with short dwells between the individual injections, combustion noise can be significantly reduced. The sound pressure level was reduced by nearly

Evaluation of anaerobic digestion post-treatment options using an integrated model-based approach

The objective of this paper is to present the main results of an engineering-research project dealing with model-based evaluation of waste streams treatment from a biotech company. This has been extensively done in domestic treatment systems, but is equally important, and with different challenges in industrial wastewater treatment. A new set of biological (activated sludge, anaerobic digestion),

Economic feasibility of building retrofitting mitigation potentials : Climate change uncertainties for Swedish cities

Deep and rapid decarbonization of the building sector requires energy demand reductions and the incorporation of renewable-energy sources. Energy retrofitting of existing buildings is a central strategy in climate mitigation and has often been highlighted as a cost-effective strategy. However, decisions on these strategies are often hampered by modeling assessments that are limited by contextual,

A spatially-restricted Younger Dryas plateau icefield in the Gaick, Scotland : Reconstruction and palaeoclimatic implications

Considerable research has been conducted in Scotland to reconstruct Younger Dryas glaciers and palaeoclimatic conditions, but our understanding remains incomplete. In this contribution, we examine the Gaick, a dissected plateau that extends over ∼520 km 2 in the Central Grampians, Scotland. The extent and style of Younger Dryas glaciation in the Gaick has been repeatedly contested, although a mo

Innate colour preferences of a hawkmoth depend on visual context

Solitary insects that feed on floral nectar must use innate knowledge to find their first flower. While innate preferences for flower colours are often described as fixed, species-specific traits, the nature and persistence of these preferences have been debated, particularly in relation to ontogenetic processes such as learning. Here we present evidence for a strong context-dependence of innate c

Crack widths in base restrained walls subjected to restraint loading

Cracks in concrete structures can have a negative impact on durability and aesthetic appearance. It is therefore important to estimate crack widths before construction, and to use suitable reinforcement amounts to limit crack widths. Crack widths are however hard to predict in restrained structures, as cracking reduces the stiffness, which in turn reduces the restraint and thereby the amount of cr

Improving requirements-test alignment by prescribing practices that mitigate communication gaps

The communication of requirements within software development is vital for project success. Requirements engineering and testing are two processes that when aligned can enable the discovery of issues and misunderstandings earlier, rather than later, and avoid costly and time-consuming rework and delays. There are a number of practices that support requirements-test alignment. However, each organis

School’s out forever? Heavy metal preferences and higher education

ObjectivesCultural behaviors are theoretically linked to future life chances but empirical literature is scant. We use heavy metal as an example of cultural identities due to its high salience. We first assess the social morphology of metal preferences in terms of socio-economic and socio-structural positions, and then asses the short term outcomes of being a heavy metal fan on education and healt

Sustaining Authoritarianism : Clientelism and Repression in Kazakhstan, Kenya, Kyrgyzstan and Tanzania

Kazakhstan, Kenya, Kyrgyzstan and Tanzania share a past and present as authoritarian states. Dominant parties are in power in Tanzania and Kazakhstan, while elections are competitive but not democratic in Kenya and Kyrgyzstan. Returns for political support (clientelism), and persecution of political adversaries and the electorate (repression), are key components in all four states. This dissertati