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Peptides that regulate food intake - Separable mechanisms for dorsal hindbrain CART peptide to inhibit gastric emptying and food intake

We investigated whether dorsal hindbrain and/or peripheral cocaine- and amphetamine-regulated transcript peptide (CARTp) acts to suppress gastric emptying of a caloric stimulus. Furthermore, effects of dorsal hindbrain CARTp on sucrose consumption and licking microstructure was studied, as well as the possible contribution of corticotropin-releasing factor (CRF) receptors to mediate effects of CAR

Development of Adenoviral Vectors for Studying Hematopoietic Stem Cell Function

Popular Abstract in Swedish Blodet innehåller några av de mest grundläggande komponenterna för mänskligt liv. Med hjälp av hjärtats pumpkraft transporterar röda blodkroppar ut syre från lungorna till de mest avlägsna delarna av kroppen via gradvis tunnare blodkärl. Livshotande blödningar stoppas via blodplättarnas koagulerande förmåga och läkande egenskaper, medan de vita blodkropparna bekämpar inHematopoietic stem cells (HSCs) are defined by their capacity to self-renew and differentiate into all hematopoietic cell lineages. Postnatally, HSCs reside predominantly in the bone marrow and are relatively rare, but important cells because of their therapeutic potential in bone marrow transplantation protocols and in their involvement in the origin of certain leukemias. To study how various gen

Minnet går gränsvakt : fyra poeter ur 1970-talets grekiska diktargeneration

Abstract in UndeterminedThe primary aim of the present study is to reveal the creative awakening of Michalis Ganas, Maria Kirtzaki, Tzeni Mastoraki and Kostas Papageorgiou, four poets of the Greek 1970s Generation. All four poets were born during the decade of the 1940s. The thesis approaches the poets entire authorship from their debut, end of 1960s beginning of 1970s, until the present day, to d

Aneurysm clip MR artifacts. Titanium versus stainless steel and influence of imaging parameters

PURPOSE: The aim of this study was to evaluate the extent to which titanium aneurysm clips could improve the quality of MR imaging compared with stainless steel clips, and to determine whether the clip artifacts could be reduced by controlling certain MR imaging parameters in frequently used pulse sequences. MATERIAL AND METHODS: The metal artifacts induced by 3 aneurysm clips were compared in 3 p

Fluoxetine potentiates chloroquine and mefloquine effect on multidrug-resistant Plasmodium falciparum in vitro

Fluoxetine (FLX), a P-glycoprotein inhibitor with antimalarial activity, is promising candidate for reversing chloroquine/mefloquine (CQ/MQ) resistance. The Dd2 strain of CQ- and MQ-resistant Plasmodium falciparum was synchronized and assayed with various concentrations of CQ/MQ individually and in combination with FLX or verapamil (VPL). Our results indicated the 50% inhibitory concentration valu

Koraller och dinoflagellater — ett marint partnerskap

Most reef-building corals live in partnership with so-called zooxanthellae in a mutually dependent way. Zooxanthellae are unicellular algae (dinoflagellates) inside the coral polyps, and by their photosynthesis they contribute to the sustenance of the coral. Corals already existed during the Cambrian period, more than 500 million years ago, bu these were very different from today's reef-building s

Effect of sweating on insulation of footwear

The study aimed to find out the influence of sweating on footwear insulation with a thermal foot model. Simultaneously, the influence of applied weight (35 kg), sock and steel toe cap were studied. Water to 3 sweat glands was supplied with a pump at the rate of 10 g/h in total. Four models of boots with steel toe caps were tested. The same models were manufactured also without steel toe. Sweating

Some topics in web performance analysis

This thesis consists of four papers on web performance analysis. In the first paper we investigate the performance of overload control through queue length for two different web server architectures. The simulation result suggests that the benefit of request prioritization is noticeable only when the capacities of the sub-systems match each other. In the second paper we present an M/G/1/K*PS queue

Ethanol and its effects on fracture healing and bone mass in male rats

Operatively induced, standardized tibia fractures in 42 10-week-old male rats were fixed with intramedullary nails. 21 of the rats were fed liquid containing 15% ethanol. 5 weeks after inducing the fracture, the rats were killed and the total body bone mineral density (BMD) was analyzed with the DEXA technique, and the mechanical properties of the fractured and the unfractured tibiae as well as th

Combustion Engine Models for Hybrid Vehicle System Development

This report is part of a project that is called Generic hybrid systems. Its objective is to simulate and investigate electric hybrid drive trains. The goal of this work has been to develop combustion engine models that are computer efficient, but still has the potential of giving both qualitative and quantitative results. For instance, if the model is run in a less ideal manner the model will show