Syftet med studien är att utforska det förbättrade upptaget av det radioaktiva spåret Technetium-99m-DTPA (99mTc-DTPA) i råtta Muskelvävnad i Fischer 344 råttor efter applicerad elektriskpulser med 1000 V / cm fältstyrka, 100 μs pulslängd och olika antal pulser.Metoder: 99mTc-DTPA (totalt 150 MBq) administrerades intramuskulärt (i.m.) vidaxel som en bolus i flera fraktioner av 50 l vardera i inte

This article investigates how economic modernization affects normative regulation by spurring formal social control in the political, economic, and private spheres as well as anomie. Multilevel negative binomial regression modeling, using World Values Survey and country-level data from 2005, predicts individual-level anomie using country-level formal-social-control indicators as well as individual

This thesis focuses on algorithms and proofs of concepts in the area of wireless systems operating with a large number of antennas, especially at the base station side.The first studied topic concerns the design and implementation of massive multiple-input multiple-output (MIMO) testbeds, primarily for communications. This is an entirely new engineering challenge on its own, due to the unprecedent

This thesis has the general aim of exploring the role of public health and medical interventions between 1880 and 1945, targeting infectious diseases, in health and income improvements in Sweden throughout the twentieth century. It applies methods of causal inference to longitudinal individual-level data from both local and national datasets combined with multisource archival data on the implement

Abstract Drawing on the concept of decoupling, from institutional theory in organizational studies, this paper explains how organizations mitigate demands for circularity. Seven Swedish apparel companies that have started collecting used clothes as a form of engagement with circular business models serve as case studies. The paper shows how outsourcing and internal separation allow these companies

The personal union between Norway and Sweden, established in 1319, has received little interest by historians, and is usually seen as terminated in 1363, if not earlier. But it was, in fact, an important factor in Scandinavian politics all the way until the establishment of the Kalmar Union under Queen Margrete in 1389. Important parts of western Sweden stayed in the union with Norway, which gave

This paper studies the role and function of corporate branding in organizational identity change, contributing to the increased scholarly interest in the organizing effects of branding, particularly corporate branding. Based on an ethnographic case study of corporate brand planning and implementation at a European telecommunications corporation, MGP, this paper demonstrates how corporate branding

In this study, steady-state laminar natural convection of Cu and TiO2 nanofluids inside different enclosures is numerically investigated. Natural convection is concerned due to a temperature difference between the hot and cold surfaces. The Boussinesq approximation is used to form the governing equations and the commercial software package ANSYS Fluent version 14.0 is used to numerically solve the

Aims: We applied near-infrared-spectroscopy (NIRS) to measure absolute frontal cerebral tissue oxygen saturation (SctO2) during head-up tilt test (HUT) in patients investigated for unexplained syncope.Methods and results: Synchronized non-invasive beat-to-beat haemodynamic monitoring, ECG, SctO2 (NIRS; normal range: 60-80%), and peripheral oxygen saturation (left hand, SpO2) were applied during HU

AIMS: Orthostatic hypotension (OH) is a cardinal sign of autonomic dysfunction and a common co-morbidity in heart failure (HF). The role of autonomic dysfunction in the development of structural cardiac anomalies in HF patients has not been sufficiently explored. We aimed to assess relations between orthostatic blood pressure (BP) responses during active standing and echocardiographic changes in a

Aim: The aim of this thesis was to identify risk factors for type 1 diabetes in children, evaluate the effects of participation in prospective follow-up and the safety of immune tolerance treatment with GAD-Alum in children with islet autoimmunity.Methods: Subjects from the Swedish DiPiS cohort were studied regarding risk factors, cord blood islet autoantibodies and the effects of early severe lif

Monoterpenoid indole alkaloids (MIAs) are plant defense compounds and high-value pharmaceuticals. Biosynthesis of the universal MIA precursor, secologanin, is organized between internal phloem-associated parenchyma (IPAP) and epidermis cells. Transporters for intercellular transport of proposed mobile pathway intermediates have remained elusive. Screening of an Arabidopsis thaliana transporter lib

Monoterpenoid indole alkaloids (MIAs) are produced as plant defence compounds. In the medicinal plant Catharanthus roseus, they comprise the anticancer compounds vinblastine and vincristine. The iridoid (monoterpenoid) pathway forms one of the two branches that feed MIA biosynthesis and its activation is regulated by the transcription factor (TF) basic helix-loop-helix (bHLH) iridoid synthesis 1 (

Plants produce many bioactive, specialized metabolites to defend themselves when facing various stress situations. Their biosynthesis is directed by a tightly controlled regulatory circuit that is elicited by phytohormones such as jasmonate (JA). The basic helix-loop-helix (bHLH) transcription factors (TFs) bHLH iridoid synthesis 1 (BIS1) and Triterpene Saponin Activating Regulator (TSAR) 1 and 2,

Anthocyanins and volatile phenylpropenes (isoeugenol and eugenol) in petunia (Petunia hybrida) flowers have the precursor 4-coumaryl coenzyme A (CoA) in common. These phenolics are produced at different stages during flower development. Anthocyanins are synthesized during early stages of flower development and sequestered in vacuoles during the lifespan of the flowers. The production of isoeugenol

Plants make specialized bioactive metabolites to defend themselves against attackers. The conserved control mechanisms are based on transcriptional activation of the respective plant species-specific biosynthetic pathways by the phytohormone jasmonate. Knowledge of the transcription factors involved, particularly in terpenoid biosynthesis, remains fragmentary. By transcriptome analysis and functio

Catharanthus roseus, the Madagascar periwinkle, synthesizes bioactive monoterpenoid indole alkaloids, including the anti-cancer drugs vinblastine and vincristine. The monoterpenoid branch of the alkaloid pathway leads to the secoiridoid secologanin and involves the enzyme iridoid synthase (IS), a member of the progesterone 5β-reductase (P5βR) family. IS reduces 8-oxogeranial to iridodial. Through