ObjectiveTo investigate the association between longitudinal changes in proton magnetic resonance spectroscopy (MRS) metabolites and amyloid pathology in individuals without dementia, and to explore the relationship between MRS and cognitive decline.MethodsIn this longitudinal multiple time point study (a subset of the Swedish BioFINDER), we included cognitively healthy participants, individuals w

Background: To elucidate the incidence of acute kidney injury (AKI) after out-of-hospital cardiac arrest (OHCA) and to examine the impact of target temperature management (TTM) and early coronary angiography on renal function. Methods: Post hoc analysis of the TTM trial, a multinational randomised controlled trial comparing target temperature of 33 °C versus 36 °C in patients with return of sponta

Rationale: Smoking is a primary risk factor for chronic bronchitis, emphysema, and chronic obstructive pulmonary disease, but since not all smokers develop disease, it has been suggested that some individuals may be more susceptible to exogenous factors, such as smoking, and that this susceptibility could be genetically determined. Objectives: The aim of the present study was to assess, in a popul

Klimatfrågan har under senare år rotat sig in i svenskens medvetande. Om detta vittnar nyord som ”klimatångest” och ”flygskam”. Det är på tiden. Men klimatförändringarna är inte den enda kris vi nu står inför och måste konfrontera.

Lexical frequency effects on word accent processing in SwedishSeveral studies have investigated the neurophysiological underpinnings of the Swedish word accents, “accent 1” and “accent 2” ([1]-[5]), which are known to have a strong association with morphology ([6]-[8]). For example, if the singular noun suffix -en is attached to the word stem bil (‘car’), the resulting word is bil1-en (‘the car’)

IntroductionA Cloud-ORiented Engine for advanced MRI simulations (coreMRI) is presented in this study. The aim was to develop the first advanced MR simulation platform delivered as a web service through an on-demand, scalable cloud-based and GPU-based infrastructure. We hypothesized that such an online MR simulation platform could be utilized as a virtual MRI scanner but also as a cloud-based, hig

PHENIX reports differential cross sections of μμ pairs from semileptonic heavy-flavor decays and the Drell-Yan production mechanism measured in p+p collisions at s=200 GeV at forward and backward rapidity (1.2

Objective: The objective of this study was to investigate lower extremity function in early rheumatoid arthritis (RA) and assess its relation to other disease parameters. Methods: An inception cohort (recruited in 1995–2005) of patients with early RA was followed according to a structured protocol. Lower extremity function was investigated at inclusion and after 1, 2, and 5 years using the Index o

The term mission in its modern meaning was coined during the expansion of western Christianity which was in many ways entangled with colonialism. The western missionary movement’s modus operandi was adopted by missions from other backgrounds as well, when economic growth and growth of revivalist Christianity have coincided. When the outcome is new churches in economically underprivileged areas, th

Study Design: Qualitative study. Introduction: An amputation injury to the hand may lead to not only impaired hand function but also psychosocial consequences. Purpose of the Study: The purpose of the study was to explore personal experiences of social participation for persons provided with an esthetic prosthesis after acquired upper limb amputation. Methods: Thirteen persons with acquired upper

Climate‐warming induced permafrost thaw exposes large amounts of carbon and nitrogen in soil at greater depths below the seasonally‐thawing active layer. The extent to which plant roots can reach and interact with these hitherto detached, deep carbon and nitrogen stores remains unknown. We aimed to quantify how permafrost thaw affects root dynamics across soil depths and plant functional types com

Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we investigated common genetic variants associated with DLB in a large European multisite sample. We performed a genome wide association study in Norwegian and European cohorts of 7

Based on all patients with tibial shaft fracture (n = 767) treated in the department of orthopedics in Malmö from 1955 to 1963, a retrospective cohort study was performed in 1990. Two hundred sixty-nine of the patients were still living in Malmö or had died in the city. Since all roentgenograms were available, all other fractures that this group of patients had sustained up to 1990 were included.