Sökresultat

HAMLET (human α-lactalbumin made lethal to tumor cells) is a protein-lipid complex that induces apoptosis-like death in tumor cells, but leaves fully differentiated cells unaffected. This review summarizes the information on the in vivo effects of HAMLET in patients and tumor models, on the tumor cell biology, and on the molecular characteristics of the complex. HAMLET limits the progression of hu

To investigate the epidemiology of infection with delta (delta) agent in a Swedish city, 181 chronic carriers of hepatitis B surface antigen (HBsAg) and 599 patients with acute, self-limited hepatitis B were analyzed for delta antigen and antibody to delta antigen (anti-delta). The study covered the period from 1970 to 1981. The delta agent was found to have been introduced to this population in 1

When a reactor is closed down the air temperature in the containment falls from about 55 °C to ambient temperature in the course of 3-4 days. Early repair and maintenance work, hence, has to be carried out in hot conditions. A common temperature during most of maintenance work is around 25-30 °C. Workers have to wear protective clothing according to the demands for each contamination zone. Heat st

A 2D numerical study of the damage accumulation at the root of a Powder Metallurgy (PM) manufactured gear wheel subjected to frequent overloads, i.e. low cycle fatigue loading, has been performed. The initial porosity distribution of the gear was obtained from a 3D simulation of double action compaction of the gear. The porosity distributions over the centre plane and at the surface were transferr

Abstract is not available.

A laboratory reactor equipped with a screw press was used for the hydrolysis of steam-SO2-exploded willow Salix caprea by a composition of Trichodemma reesei and Aspergillusfoetidus enzyme preparations at high substrate concentration. Optimal conditions providing the maximal volume of hydrolysis syrup with maximal sugar concentrations were determined. Two different hydrolysis procedures were devel

A new classification system indicating type and severity of language disorder was applied by five speech pathologists. They independently interpreted information from the initial language assessment of 39 children with developmental language disorder (DLD), who had been assessed by one of the present authors before age 3;6. Information about planned intervention was also collected. The children we

Large numbers of blood cells need to be continuously replaced in order to sustain the crucial functions of the immune system, oxygen transport and blood clotting. The large diversity of cell types required to maintain the integrity of the blood system are all produced from blood forming or hematopoietic stem cells (HSCs). HSCs have the unique property of self renewal, ensuring life-long replenishm

Dijet production in deep inelastic ep scattering is investigated in the region of low values of the Bjorken-variable x (10(-4) < x < 10(-2)) and low photon virtualities Q(2) (5 < Q(2) < 100 GeV2). The measured dijet cross sections are compared with perturbative QCD calculations in next-to-leading order. For most dijet variables studied, these calculations can provide a reasonable description of th

A summary of a study devoted to computerized scheduling of a complex integrated pulp and paper mill is presented. A mathematical model of the mill was built and the scheduling problem was formulated as an optimal control problem for a multivariable deterministic system. The mill is described by a linear, first-order, vectorvalued differential equation. The control system consists of 10 state varia

To evaluate mechanisms underlying the close association between insulin secretion and insulin sensitivity, insulin sensitivity was evaluated by the euglycemic-hyperinsulinemic clamp technique (M/I(clamp)) and insulin secretion was determined from the 75-g oral glucose tolerance test (OGTT) and from the glucose-dependent arginine-stimulation test in 81 nondiabetic postmenopausal women, all aged 61