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All-atomic and coarse-grained molecular dynamics investigation of deformation in semi-crystalline lamellar polyethylene

In the present work we have performed classical molecular dynamics modelling to investigate the effects of different types of force-fields on the stress-strain and yielding behaviours in semi-crystalline lamellar stacked linear polyethylene. To this end, specifically the all-atomic optimized potential for liquid simulations (OPLS-AA) and the coarse-grained united-atom (UA) force-fields are used to

Origins and pathways of innovation in the third industrial revolution.

This study examines the factors that shaped the long-term evolution of the ICT industry in Sweden, 1950-2013. Using a new historical microdatabase on actual innovation output, the driving forces and technological interdependencies in the third industrial revolution are chronicled. The results of this study support some stylized facts about technological interdependencies in general-purpose technol

Observation of Higgs boson production in association with a top quark pair at the LHC with the ATLAS detector

The observation of Higgs boson production in association with a top quark pair (tt¯H), based on the analysis of proton–proton collision data at a centre-of-mass energy of 13 TeV recorded with the ATLAS detector at the Large Hadron Collider, is presented. Using data corresponding to integrated luminosities of up to 79.8 fb−1, and considering Higgs boson decays into bb¯, WW⁎, τ+τ−, γγ, and ZZ⁎, the

Prenatal diagnosis of haemophilia

Prenatal diagnosis of haemophilia A or B is possible by means of chorionic villus biopsy in the first trimester which traces the mutation or informative genetic markers. If possible, direct gene analysis of the mutation is preferred, The natural starting point in haemophilia A is to ascertain whether the disease is due to inversion in the X-chromosome, which is the case in almost half of the sever

Determination of factor IX allotypes for carrier identification in haemophilia B

The existence of two genetic variants (allotypes) of normal human factor IX is used for carrier detection in three families with severe and one with mild haemophilia B. By analysis of IX:Ag with two different monoclonal antibodies in 93 members of the families, allelic assignment is shown to be a complement in carrier diagnosis to genotypic DNA studies. Allelic assignment makes possible a reliable

Practical aspects of extended half-life products for the treatment of haemophilia

Haemophilia A and haemophilia B are congenital X-linked bleeding disorders caused by deficiency of coagulation factor VIII (FVIII) and IX (FIX), respectively. The preferred treatment option for patients with haemophilia is replacement therapy. For patients with severe disease, prophylactic replacement of coagulation factor is the treatment of choice; this has been shown to reduce arthropathy signi

Slowing Down Type II Migration of Gas Giants to Match Observational Data

The mass and semimajor axis distribution of gas giants in exoplanetary systems obtained by radial velocity surveys shows that super-Jupiter-mass planets are piled up at 1 au, while Jupiter/sub-Jupiter-mass planets are broadly distributed from ∼0.03 au to beyond 1 au. This feature has not been explained by theoretical predictions. In order to reconcile this inconsistency, we investigate evolution o

Revealing timid pseudo-scalars with taus at the LHC

A light pseudo-scalar that is copiously produced at the LHC may still be allowed by present searches. While masses above 65 GeV are effectively covered by di-photon searches, the lower mass window can be tested by a new search for boosted di-tau resonances. We test this strategy on a set of composite Higgs models with top partial compositeness, where most models can be probed with an integrated lu

Shared spaces: Artistic methods for collaborative works

Teatr Weimar is a performing arts collective founded in 2003 and located in Malmö, Sweden. The group brings together playwrights, directors, actors, musicians and other artists to explore the boundaries and expressive potential of contemporary performing arts. The works of the collective are syntheses of traditional and experimental theatre, new music theatre, concert music, radiophonic art, video

Resonances and Responses

The idea of resonances and responses as a fundamental compositional principle is found in many of my compositions. I have used it in instrumental pieces both with and without electronics, in theatre contexts, in conceptual works and in intertextual and intermusical referential structures. In Terpsichord, a piece for percussion and pre-recorded sounds, the resonances from the acoustic instruments f

Membrane processes for a sustainable future: Moving from C2/C3 chemistry to biotechnogical processes

The global society has started a journey from using fossil-based raw material to the utilisation of climate-smart sustainable raw materials. Biorefineries have been identified as one of the backbones of the new bioeconomy using fermentation processes to convert biomass to biofuels and –chemicals and thus replacing the conventional C2/C3 chemistry with biotechnological processes. In current petro-c

The relation between structure-performance of thin film composite membranes and the tools used for their fabrication method

For more than 30 years polyimides (PA) have been one of the main polymers for the fabrication of thin film composite membranes. Several researchers have assessed the main fabrication variables that influence the final structure of the polyamide layers including monomer concentration, solvents, additives in aqueous and organic phases and type of support to mention few [1,2]. However, few studies ha

Separations in biorefineries

1. IntroductionThe starting point of modern biotechnology is often defined by the production of lactic acid by Pasteur in 1857 and the discovery of penicillin by Fleming in 1928. During this first wave of biotechnological processes moved production of e.g. antibiotics and amino acids from laboratory to industrial scale. The second wave of biotechnological processes started with the discovery of th

Champs d'étoiles

Champs d'étoiles is a musical suite that builds on texts and thoughts on the pilgrimage as a quest for deeper insights into the timeless mystery of being human. The work is also about musical timelessness. I have always been deeply fascinated by the music and instruments from the Renaissance and Baroque eras and this work is about new music for period instruments. The close collaboration with the

Lymph node CXCL17 messenger RNA : A new prognostic biomarker for colon cancer

Lymph node metastasis is the most important prognostic characteristic of colorectal cancer. Carcinoembryonic antigen messenger RNA was shown to detect tumor cells that have disseminated to lymph nodes of colorectal cancer patients and to be at least as good as the hematoxylin and eosin method to predict survival in colorectal cancer patients. CXCL17 was recently shown to be ectopically expressed i

In vivo detection of alzheimer’s disease

Recent revisions to the diagnostic criteria for Alzheimer’s disease (AD†) incorporated conceptual advances in the field. Specifically, AD is now recognized to encompass a continuum, spanning from preclinical (accruing brain pathology in the absence of symptoms) through symptomatic predementia (prodromal AD, mild cognitive impairment) and dementia phases. The role of biological markers (biomarkers)