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The recently discovered glymphatic system, which supports brain-wide clearance of metabolic waste, has become the subject of intense research within the past few years. Its nomenclature arose due to its functionally analogous nature to the lymphatic system in combination with glial cells that are part of its anatomical boundaries. The influx of cerebrospinal fluid (CSF) from perivascular spaces in
Background: Birth positions may influence the risk of tears in the genital tract during birth. Birth positions are widely studied yet knowledge on genital tract tears following birth on a birth seat is inconclusive. Aim: The objective of this study was to describe the proportion of genital tract tears in women who gave birth on a birth seat compared to women who did not. Method: An observational c
Results of dedicated Monte Carlo simulations of beam-induced background (BIB) in the ATLAS experiment at the Large Hadron Collider (LHC) are presented and compared with data recorded in 2012. During normal physics operation this background arises mainly from scattering of the 4 TeV protons on residual gas in the beam pipe. Methods of reconstructing the BIB signals in the ATLAS detector, developed
The Tsenkher structure in the Gobi-Altai, Mongolia is a c. 3.7 km diameter crater with a well-preserved ejecta blanket. It has been hypothesized to be either of impact or volcanic origin in our previous work. Observations during our 2007 expedition and related sample analyses give further support for an impact origin. The evidence includes the presence of a structurally uplifted near-circular rim
HER2/ErbB2 activation turns on transcriptional processes that induce local invasion and lead to systemic metastasis. The early transcriptional changes needed for ErbB2-induced invasion are poorly understood. Here, we link ErbB2 activation to invasion via ErbB2-induced, SUMO-directed phosphorylation of a single serine residue, S27, of the transcription factor myeloid zinc finger-1 (MZF1). Utilizing
Determining accurate rates of benthic nitrogen (N) removal and retention pathways from diverse environments is critical to our understanding of process distribution and constructing reliable N budgets and models. The whole-core 15N isotope pairing technique (IPT) is one of the most widely used methods to determine rates of benthic nitrate-reducing processes and has provided valuable information on
BACKGROUND: Many countries lack sufficient medical doctors to provide safe and affordable surgical and emergency obstetric care. Task-sharing with associate clinicians (ACs) has been suggested to fill this gap. The aim of this study was to assess maternal and neonatal outcomes of caesarean sections performed by ACs and doctors. METHODS: All nine hospitals in Sierra Leone where both ACs and doctors
I kapitlet diskuteras vilka litteraturhistoriska föreställningar om arbetarlitteratur som styr dagens svenska arbetarlitteratur. Dagens varianter skildrar i stor utsträckning samhällets trasproletariat och tycks därmed ha mer gemensamt med exempelvis Maksim Gorkijs noveller från 1890-talet än med trettiotalets klassisk-kanoniska svenska arbetarskildringar. Hur kan det komma sig? Vad säger denna li
The selection pressures that drive flight feather morphology are poorly understood. Using a phylogenetic comparative approach and data from 178 species of birds, we investigated whether both position along the wing length and flight feather length affected vane structure. We found that barb density was lower on distal primaries than on proximal primaries of the leading feather vane. In contrast, oThe selection pressures that drive flight feather morphology are poorly understood. Using a phylogenetic comparative approach and data from 178 species of birds, we investigated whether both position along the wing length and flight feather length affected vane structure. We found that barb density was lower on distal primaries than on proximal primaries of the leading feather vane. In contrast, o
The exegetical subjects have a particular interdisciplinary role within academia, implying that their responsibilities and significance are – and should be – under constant debate. In his article, church historian Joel Halldorf, argues for the overt use of theological interpretations (in the narrow sense of "normative theology") in the exegetical discipline. Halldorf thereby highlights some currenThe exegetical subjects have a particular interdisciplinary role within academia, implying that their responsibilities and significance are – and should be – under constant debate. In his article, church historian Joel Halldorf, argues for the overt use of theological interpretations (in the narrow sense of "normative theology") in the exegetical discipline. Halldorf thereby highlights some curren
Central sensitization is a condition in which there is an abnormal responsiveness to nociceptive stimuli. As such, the process may contribute to the development and maintenance of pain. Factors influencing the propensity for development of central sensitization have been a subject of intense debate and remain elusive. Injury-induced secondary hyperalgesia can be elicited by experimental pain model
Aim: To study health-related quality of life (HRQoL) in children with idiopathic clubfoot (IC) and the influence of sex, clubfoot laterality and neurodevelopmental difficulties (NDD) on HRQoL. Methods: A cross-sectional questionnaire-based study in Stockholm and Skåne Counties, Sweden, of 106 children with IC born 2004–2007 (mean 9.4 ± 0.6 years) and a general population sample of 109 schoolchildr
Today, more than ever, ‘Spaceship Earth’ is an apt metaphor as we chart the boundaries for a safe planet1. Social scientists both analyse why society courts disaster by approaching or even overstepping these boundaries and try to design suitable policies to avoid these perils. Because the threats of transgressing planetary boundaries are global, long-run, uncertain and interconnected, they must be
This work evaluates the performance and emissions of the series hybrid vehicle concept powered by a gasoline partially premixed internal combustion engine. To do so, experimental data was collected from a Volvo VED-D4 Euro 6 four-cylinder compression ignition engine running under gasoline partially premixed combustion. Two series hybrid vehicle models were developed in GT-Power®, which were fed wi
