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The complex 12+ which has two pendant 4-pyridyl substituents may be viewed as a metal-containing analogue of 4,4′-bipyridine. The complex undergoes N-alkylation reactions with a variety of alkylating agents to give more highly functionalised tetracationic complexes which may be termed metalloviologens by analogy with viologens. These complexes may also be prepared by alkylation of the free ligands
The reaction of [Os3H2(CO)10] with Me3SiC2C2SiMe3 affords both [Os3(μ-H) (CO)10{μ-η1-η2-HC 2(SiMe3)C2(SiMe3)}] (1) and [Os3(μ-CO)(CO)9(μ3-η 2-Me3SiC2C2SiMe3)] (2) in good yield, 2 being favoured with an excess of diyne. In 1, one edge of the triosmium unit is bridged by the vinyl moiety of a transformed bis(trimethylsilyl)-1,4-butadiyne ligand that has undergone a hydride transfer and a 1,2-trimet
In this study the effect of cholesterol in Langmuir-Blodgett monolayers of fatty acids of varying chain lengths was investigated by atomic force microscopy (AFM). Domain formation due to lateral phase separation was studied at different lipid compositions and surface pressures. A small amount of cholesterol is miscible with palmitic acid (C16:0) and forms a flat monolayer while excess cholesterol
Monolayers of palmitic (C16:0) and lignoceric acid (C24:0) and their equimolar mixture were transferred to a hydrophilic mica substrate at various surface pressures and investigated by means of atomic force microscopy (AFM) in contact and lateral force modes. The first-order transition of lignoceric acid gives a plateau region, representing a liquid expanded to liquid condensed phase transition in
Abstract: Territorial species are unlikely to show extensive movements between breeding seasons. This is especially true for long-lived species, which often have strong pair bonding and can occupy the same territory for years. However, also in such species, individuals may face situations that can lead to a territory shift. Here, we use a comprehensive dataset documenting 40 years of breeding beha
Amassing the available solar energy over the Sahara desert, through the installation of a large-scale solar farm, would satisfy the world’s current electricity needs. However, such land use changes may affect the global carbon cycle, possibly offsetting mitigation efforts. Here a fully coupled Earth System model EC-Earth was used to investigate the impact of a Saharan solar farm on the terrestrial
Aims: Recent evidence supports non-class cardioprotective effects of metoprolol against neutrophil-mediated ischemia-reperfusion injury during exacerbated inflammation. Whether metoprolol exerts direct anti-inflammatory effect on cardiomyocytes is unknown. Accordingly, we aimed to investigate the direct anti-inflammatory effects of metoprolol in a cellular model of human induced pluripotent stem c
In the present study, digestion pattern of purified bovine κ-casein (κ-CN) variants A, B, E as well as desialylated variant B, using INFOGEST 2.0 in vitro gastrointestinal digestion were investigated using peptidomics. Peptide profiles of the digests were identified and quantified using ion abundancies by liquid chromatography electrospray quadropole time of flight mass spectrometry (LC-ESI/Q-TOF
Materials, when sintered at high temperatures, undergo structural changes on multiple, hierarchical length scales but getting realtime information on these changes is difficult. To address this challenge, we developed a custom-built sample environment that allows us to investigate the structural evolution of materials during sintering using high-energy two-dimensional synchrotron X-ray diffraction
In Fontan patients, a lung deprived of hepatic blood may develop pulmonary arterio-venous malformations (PAVMs) resulting in shunting, reduced pulmonary vascular resistance (PVR) and decreased oxygenation. To provide guidance for corrective invasive interventions, we aimed to non-invasively determine how the hepatic to pulmonary blood flow balance correlates with pulmonary flow, PVR, and with oxyg
Bacterial lipopolysaccharide (LPS) induces rapid protein aggregation in human wound fluid. We aimed to characterize these LPS-induced aggregates and their functional implications using a combination of mass spectrometry analyses, biochemical assays, biological imaging, cell experiments, and animal models. The wound-fluid aggregates encompass diverse protein classes, including sequences from coagul
A hyperspectral field sensor (FloX) was installed in Adventdalen (Svalbard, Norway) in 2019 as part of the Svalbard Integrated Arctic Earth Observing System (SIOS) for monitoring vegetation phenology and Sun-Induced Chlorophyll Fluorescence (SIF) of high-Arctic tundra. This northernmost hyperspectral sensor is located within the footprint of a tower for long-term eddy covariance flux measurements
Inconsistent reporting of outcomes in clinical trials of treatments for whiplash associated disorders (WAD) hinders effective data pooling and conclusions about treatment effectiveness. A multidisciplinary International Steering Committee recently recommended 6 core outcome domains: Physical Functioning, Perceived Recovery, Work and Social Functioning, Psychological Functioning, Quality of Life an
Background: Patients in the forensic mental health services (FMHS) with a mental disorder, a co-occurring substance use disorder (SUD), and high risk of aggressive antisocial behavior (AAB) are sometimes referred to as the ‘triply troubled’. They suffer poor treatment outcomes, high rates of criminal recidivism, and increased risk of drug related mortality. To improve treatment for this heterogene
This chapter considers the creation of the Later Life Audio and Radio Co-operative (LLARC) as an outcome of a participatory action research (PAR) project with a focus on facilitating later life civic participation. Developed in the UK, but with potential to become a global initiative, the LLARC is a collaborative network of older content creators, age-friendly radio stations, third-sector organisa
Context. Gaia Data Release 3 (Gaia DR3) contains the second release of the combined radial velocities. It is based on the spectra collected during the first 34 months of the nominal mission. The longer time baseline and the improvements of the pipeline made it possible to push the processing limit from GRVS= 12 in Gaia DR2 to GRVS= 14 mag. Aims. We describe the new functionalities implemented for
Walking and biking are active transport modes, that may be part of sustainable transport chains, thereby reducing car use. In the scientific literature, they have commonly been investigated separately (e.g. Ewing et al., 2006; Kellstedt et al., 2021), but since pedestrians and cyclists often share the same environments, it makes sense to consider them jointly. This research proposes a conceptual m
