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Background: The combination of infliximab and immunosuppressant therapy is a standard management strategy for patients with Crohn's disease. Concerns regarding the implications of long-term combination therapy provided the rationale for a formal clinical trial of treatment de-escalation. Our aim was to compare the relapse rate and the time spent in remission over 2 years between patients continuin

Background & Aims: Industrial foods have been associated with increased risks of several chronic conditions. We investigated the relationship between the degree of food processing and risks of Crohn's disease (CD) and ulcerative colitis (UC) in the European Prospective Investigation into Cancer and Nutrition cohort. Methods: Analyses included 413,590 participants (68.6% women; mean baseline ag

Background: Accumulation of saturated fatty acids (SFAs) in the liver is known to induce hepatic steatosis and inflammation causing non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Although SFAs have been shown to affect the epigenome in whole blood, pancreatic islets, and adipose tissue in humans, and genome-wide DNA methylation studies have linked epigenetic ch

Background: Diet may impact important risk factors for endometrial cancer such as obesity and inflammation. However, evidence on the role of specific dietary factors is limited. We investigated associations between dietary fatty acids and endometrial cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: This analysis includes 1,886 incident endometrial ca

Background: Women with current or previous drug use (WCPDU) have an increased risk of poor breast and cervical cancer outcomes. Screening is known to decrease the mortality of these common cancer forms, but screening participation has been sparsely investigated among women with drug dependency. The aim of this study was to assess participation in screening for breast and cervical cancer among WCPD

COVID-19 is a major public health threat associated with the increased global burden of infectious diseases, mortality, and enormous economic loss to countries and communities. Safe and efficacious COVID-19 vaccines are crucial in halting the pandemic. We assessed the COVID-19 vaccine uptake and associated factors among community members from eight regions in Tanzania. The interviewer-administered

Inlägg på The Climate Change and the Rule of LawPosting at The Climate Change and the Rule of Law

What counts as environmental law adjudication? Or to put it differently; how do we decide which cases demand attention in an environmental law journal, such as this one? Is it the relevance of environmental legislation to the court’s legal reasoning, or would the mere reference to environmental problems and their related laws do? In either case, the net is cast wide. Environmental disputes are und

Infrastructure is often viewed through global and promotional lenses, particularly its role in creating market connectivity. However, infrastructure is heavily dependent on and constitutive of local spaces, where ‘frictions’, or disputes, emerge. Drawing on the Belt and Road Initiative (BRI) as a case study, we examine in detail two cases of BRI-related climate change litigation – one in Pakistan,

Can there be a silver lining to a pandemic? Lockdown, a common response to COVID-19 by governments across the world, dramatically changed peoples’ lives by confining their movement to their homes. It thus also changed our transportation and consumption patterns, leading to huge reductions in emissions.1 Images snapped by NASA and the European Space Agency showing clouds of nitrogen dioxide disappe

A growing global wave of climate change litigation is led by minors, relying on their human rights, as well as those of future generations against governments and their failure to take action on climate change. Such litigation is emerging also before the Court of Justice of the European Union, where the ambitiousness of the EU’s climate change policies, embodied in the 2030 Climate and Energy Poli

The genus Amorphophallus is an economically important taxon that is abundant in Old World tropical forests (Asia, Oceania and Africa). It includes many species that are used with increasing frequency as a source of food and pharmaceutical products worldwide. Amorphophallus konjac is an important economic crop and has been used widely in China and Japan for commercial konjac glucomannan (KGM) produ

Two series of samples collected for isolation of dictyostelid cellular slime molds (dictyostelids) in Madagascar yielded a relatively large number of isolates of Polysphondylium. Most of these turned out to be species new to science that show varying degrees of clustering from unclustered to coremiform as well as an ability to migrate. Migratory ability (phototaxis) is a common feature of species

The phylogenetic position of the Afro-Asian genus Sphaerocoma is investigated using DNA sequences from plastid rps16 and ndhF, as well as from nuclear ITS and RPB2. Seven accessions of Sphaerocoma, representing all three currently recognized taxa, are analyzed along with sequences from genera that have been found to be closely related to Sphaerocoma in broader studies of Caryophyllaceae. The Afro-

In the wake of crises and “enlargement fatigue”, EU politics deprioritized enlargement. Recently, however, the Commission motioned a reinvigorated enlargement prospect for the Western Balkans, identifying Serbia and Montenegro as the front runners. This paper advises that in going forward, the EU should also look back at its five decades of enlargement. The article focuses on environmental protect