Investigations of New Biomimetic Transamination Systems and Inclusion Complexation with Cyclodextrins.
Popular Abstract in Swedish Avhandlingen behandlar ett syntetiskt system för en process som liknar den kroppsegna processen för metabolism av aminosyror (transaminering). Avhandlingen behandlar också de fundamentala krafter som ligger bakom inbindningen av olika substrat i enzym. Även detta är studerat genom starkt förenklade modellsystem, bestående av cykliska strukturer uppbyggda av glukosenhetTwo new transamination systems are described. The first example is a dibenzo[a,d]- cycloheptene containing system, designed to accomplish a [1,3]-hydride transfer. Several catalysts have been examined for this purpose. tris-Pentafluorophenyl borane was found to be the most efficient catalyst. The stereochemistry of several closely related dibenzo[a,d]- cycloheptene have also been examined, display