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Capsaicinoids are bioactive alkaloids produced by the chili pepper fruit and are known to be the most potent agonists of the human pain receptor TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1). They are currently produced by extraction from chili pepper fruit or by chemical synthesis. Transfer of the biosynthetic route to a microbial host could enable more efficient capsai

Transcription factor-based biosensors represent promising tools in the construction and evaluation of efficient cell factories for the sustainable production of fuels, chemicals and pharmaceuticals. They can notably be designed to follow the production of a target compound or to monitor key cellular properties, such as stress or starvation. In most cases, the biosensors are built with fluorescent

BackgroundCapsaicinoids are produced by plants in the Capsicum genus and are the main reason for the pungency of chili pepper fruits. They are strong agonists of TRPV1 (the transient receptor potential cation channel subfamily V member 1) and used as active ingredients in pharmaceuticals for the treatment of pain. The use of bioengineered microorganisms in a fermentation process may be an effi

Let (G, g) be a 4-dimensional Riemannian Lie group with a 2-dimensional left-invariant, conformal foliation F with minimal leaves. Let J be an almost Hermitian structure on G adapted to the foliation F . We classify such structures J which are almost Kähler (AK), integrable (I) or Kähler (K). Hereby we construct several new multi-dimensional examples in each class.

Soil and groundwater contamination is an increasingly recognised threat to public health and the environment around the globe. New types of contaminants continue to emerge, and awareness of their threat, continues to develop. Many countries have national clean-up programs with priority lists of the most hazardous contaminated sites. Investigation and remediation of these sites, however, take a lon

European settler colonies are often thought to have been characterized by a continued expansion of the landed frontier, which impacted the distribution of wealth across their settler populations. Hampered by a lack of data, few studies have been able to study this in-depth. How does settlement timing affect wealth and wealth accumulation when frontier expansion is not a smooth continuous process?

Den här boken riktar sig till ”utvecklande praktiker” samt till alla som är intresserade av innovation i offentlig sektor och förändringsarbete i samverkan mellan forskning och praktik. Den riktar sig även till dem som har intresse av sakfrågor som berörts av de fem hypoteslabb som ingått i projektet Den (ut)forskande staden:• Gestaltad livsmiljö – om hur vi kan samverka mellan olika värden, exemp

Inledningskapitel till forskningsantologin "De (ut)forskande staden - En FoU-innovation i offentlig sektor" med fokus på hur innovation i offentlig sektor förhåller sig till begreppet livskvalitet och hur medborgarinvolvering och sektorsövergripande arbete kan påverka kvaliteten i offentlig sektor.

This article offers a history of the digital music archive at the Danish Broadcasting Corporation (DR). By looking into archival documents, reviewing interviews and analyzing interfaces, the article examines visions and strategies behind the digital music archive and its in-house platform, /Diskoteket, and based on this the article assesses whether or not DR’s archival strategies play an active ro