HTSeq 2.0 provides a more extensive application programming interface including a new representation for sparse genomic data, enhancements for htseq-count to suit single-cell omics, a new script for data using cell and molecular barcodes, improved documentation, testing and deployment, bug fixes and Python 3 support.

Background: Opioid substitution treatment (OST) populations are aging and have increased mortality and somatic morbidity compared to general populations internationally. While OST patients have poor self-rated physical health and unmet healthcare needs, documented healthcare utilization has been sparsely investigated. The aim of this study was to assess registered healthcare utilization for somati

Recent studies have shown that dissolved organic matter (DOM) decomposed by ectomycorrhizal (ECM) fungi increases adsorptive properties of organic matter towards soil mineral surfaces. Concomitantly, ECM fungi secrete secondary metabolites with iron reducing capacity that are thought to participate in non-enzymatic Fenton-based decomposition of DOM. The aim of this study was to investigate if the

Computational models for predicting the early course of the COVID-19 pandemic played a central role in policy-making at regional and national levels. We performed a systematic review, data synthesis, and secondary validation of studies that reported on prediction models addressing the early stages of the COVID-19 pandemic in Sweden. A literature search in January 2021 based on the search triangle

Purpose: To compare collagenase injection with surgical fasciectomy in Dupuytren disease (DD) for the prevalence of contracture in treated fingers 5 years after treatment. Methods: This was a single-center, comparative cohort study comprising 2 cohorts of patients treated for DD in 1 or more of 3 ulnar fingers with collagenase injection (159 patients) or surgical fasciectomy (59 patients). At 5 ye

In anonymous online text-based counselling provided by social services, counsellors face specific communicative and professional challenges. Among other things, they need to ensure that they have understood the chat users correctly in order to provide relevant information and advice. The paper studies how counsellors check their understanding of users’ situations by using formulations, namely, sum

Background: Atrial septal defect (ASD) results in a left-to-right shunt causing right-ventricular (RV) volume overload and decreased cardiac output from the left ventricle. Pressure–volume (PV) loops enable comprehensive assessment of ventricular function and might increase understanding of the pathophysiology of ASD. The aim of this study was to investigate if left-ventricular (LV) haemodynamic r

Background: Norm values for patient reported outcomes, that is knowledge about how the general population of women rate their breast-related satisfaction and quality of life, are necessary to interpret the meaning of scores. The aims of this study were to create Swedish normative values for the BREAST-Q reduction/mastopexy module and to describe what healthy women are most satisfied/dissatisfied w

The purpose was to investigate stress among adolescents (16–19 years old) during the coronavirus disease 2019 (COVID-19) pandemic. Focus group (n = 9) interviews with students at upper secondary schools (16–19 years old, n = 41) were conducted in southern Sweden during the COVID-19 pandemic in 2021. The interviews were analyzed by qualitative content analysis. The analysis revealed five categories

The Great Green Wall (GGW) Initiative aims at combatting land degradation while achieving socio-economic development across the Sahel through a mosaic of sustainable land management (SLM) and restoration practices. As the Global Environment Facility (GEF) is the main funding mechanism for land degradation neutrality related projects, we have analyzed its previous SLM projects in four pilot countri

Induction heating is used in many industrial applications to heat electrically conductive materials. The coupled electromagnetic-thermal induction heating process is non-linear in general, and for ferromagnetic materials it becomes challenging since both the electromagnetic and the thermal responses are non-linear. As a result of the existing non-linearities, simulating the induction heating proce

A nursing programme in southern Sweden was revised to meet future demands. The aim of this study was to explore important conceptual areas to be included in a nursing programme in order to meet long-term societal and health care requirements. Group concept mapping (GCM), a mixed-methods approach, was used. Thirty-four experienced teachers participated. Data was collected during brainstorming sessi

Titanium is widely employed in aerospace space, where the surface integrity plays an important role in part quality. This paper presents the numerical and experimental results of residual stress when machining Titanium based on a CEL (Coupled Eulerian-Lagrangian) method. The performance of proposed model is compared with LAG (Lagrangian) and ALE (Arbitrary Lagrangian-Eulerian) methods regarding se

Induction hardening is widely used in the industry as a surface heat treatment that improves the surface and the subsurface hardness of components greatly. The hardened case, which usually is a few mm, highly impacts the surface and structural integrity of the component. In this work, we simulate the scanning induction hardening process by means of finite element modeling. The computed hardness, m

Future climate warming in the Arctic will likely increase the vulnerability of soil carbon stocks to microbial decomposition. However, it remains uncertain to what extent decomposition rates will change in a warmer Arctic, because extended soil warming could induce temperature adaptation of bacterial communities. Here we show that experimental warming induces shifts in the temperature–growth relat

Supply chain visibility (SCV) has been gaining recognition in recent years as a key factor for achieving analytical capabilities and improving supply chain performance. However, levels of SCV implementation lag behind current technological advances. This research was motivated by the lack of visibility in inbound logistics, which limits the possibility of managing deviation, in particular concerni

Background and purpose — Total knee replacement (TKR) studies usually analyze all-cause revision when con-sidering relationships with patient and prosthesis factors. We studied how these factors impact different revision diagnoses. Patients and methods — We used data from 2003 to 2019 of TKR for osteoarthritis from the arthroplasty regis-tries of Sweden, Australia, and Kaiser Permanente, USA to st

Molecular oxygen and carbon dioxide may be limited for aquatic plants, but they have various mechanisms for acquiring these gases from the atmosphere, soil, or metabolic processes. The most common adaptations of aquatic plants involve various aerenchymatic structures, which occur in various organs, and enable the throughflow of gases. These gases can be transferred in emergent plants by molecular

This paper introduces a novel model to predict ice accretion in glaze ice conditions due to supercooled water droplets. Glaze icing is controlled by a large number of interacting physical phenomena. The purpose of the suggested model was to offer a faster alternative to explicitly modelling these phenomena. The paper presents the suggested model and investigates the sensitivity of the predictions