Sökresultat

Filtyp

Din sökning på "*" gav 533460 sökträffar

Pathway-specific bidirectional regulation of Ca2+/calmodulin-dependent protein kinase II at spinal nociceptive synapses after acute noxious stimulation.

An intensely painful stimulus may lead to hyperalgesia, the enhanced sensation of subsequent painful stimuli. This is commonly believed to involve facilitated transmission of sensory signals in the spinal cord, possibly by a long-term potentiation-like mechanism. However, plasticity of identified synapses in intact hyperalgesic animals has not been reported. Here, we show, using neuronal tracing a

How migrants get there: Migratory performance and orientation

Migratory animals show a suite of adaptations to cope with their journeys. These include not only morphological features for efficient locomotion and storage of energy but also behavioral adjustments to exploit winds and currents or to avoid drift caused by moving fluids. Migration strategies across locomotory modes can be analyzed in the context of optimality models, using some general principles

Ion Current Sensing for HCCI Combustion Feedback

Measurement of ion current signal from HCCI combustionwas performed. The aim of the work was to investigateif a measurable ion current signal exists and if it is possible to obtain useful information about the combustion process. Furthermore, influence of mixture quality in termsof air/fuel ratio and EGR on the ion current signal wasstudied. A conventional spark plug was used as ionizationsensor.

Circular Reference Attributed Grammars - their Evaluation and Applications

This paper presents a combination of Reference Attributed Grammars (RAGs) and Circular Attribute Grammars (CAGs). While RAGs allow the direct and easy specification of non-locally dependent information, CAGs allow iterative fixed-point computations to be expressed directly using recursive (circular) equations. We demonstrate how the combined formalism, Circular Reference Attributed Grammars (CRAGs

Functional characterization of the CCL25 promoter in small intestinal epithelial cells suggests a regulatory role for caudal-related homeobox (Cdx) transcription factors

The chemokine CCL25 is selectively and constitutively expressed in the small intestinal epithelium and plays an important role in mediating lymphocyte recruitment to this site. In this study, we demonstrate that CCL25 expression in murine small intestinal epithelial cells is independent of signaling through the lymphotoxin 0 receptor and is not enhanced by inflammatory stimuli, pathways involved i

Radiological changes in asbestos cement workers

OBJECTIVE--To explore associations between exposure to asbestos cement dust and radiographic findings in lung parenchyma and pleura. METHODS--Radiographs from 174 blue collar workers and 29 white collar workers from an asbestos cement plant formed one part of the study. Progression of small opacities was further studied in those 124 blue collar workers, for whom two radiographs taken after the end

Justin and Stoic Cosmo-Theology

Abstract in UndeterminedDue to his background as a Platonist, Justin Martyr’s relation to Stoic philosophy has not gained as much attention from scholars as his relation to Platonism, and his relationship to contemporary Stoicism has been largely overlooked. The present essay provides an overview and analysis of Justin’s references and allusions to Stoics and Stoic philosophy, with particular focu

Composite Material Based on Macroporous Polyaniline and Osmium Redox Complex for Biosensor Development

Here the feasibility of layers based on the conducting polymer polyaniline (PANI) as component of glucose biosensors using glucose oxidase (GOx) as enzyme and [Os(bpy)(2)(4-aminomethylpyridine)Cl]PF6 (OsCmplx) as electrochemical mediator, is evaluated. Particularly, PANI was employed to obtain a nanostructured macroporous material (m-PANI) around polystyrene nanoparticles taken as template and the

A modified LLC panel unit root test of the PPP hypothesis

In a recent study,Westerlund (Empir Econ 37:517–531, 2009) shows that the performance of the popular LLC (Levin et al., J Econ 108:1–24, 2002) panel unit root test depends critically on the choice of lag truncation used when correcting for serial correlation, and that it is only when this parameter is set as a function of time that the power raises above size. The purpose of the current paper is t

Separation and Further Characterization of Hematopoietic Cell Populations Based on Phenotypic and Biophysical Properties

Hematopoietic stem cells (HSC) are multipotent and possess self-renewal capacity. Thus, they can sustain a life-long hematopoiesis and are also capable of restoring the hematopoietic system when transplanted to a patient. In allogeneic hematopoietic stem cell transplantation (HSCT), a potent graft-versus-leukemia (GvL) effect must be balanced against the concomitant risk of severe immunological re

Motor development following in utero exposure to organochlorines: a follow-up study of children aged 5-9 years in Greenland, Ukraine and Poland

Background: Prior studies on the association between prenatal exposure to polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (DDE) and child motor development have found contradicting results. Using data collected in the INUENDO cohort in Kharkiv (Ukraine), Warsaw (Poland) and Greenland (N = 1,103) between the years 2002 and 2012, we examined relations of prenatal exposure to 1,

A relationship between migraine and biliary tract disorders: findings in two Swedish samples of elderly twins

Objectives - To investigate whether there is a relationship between the clinical occurrence of migraine and biliary tract disorders (BTD) and to study whether there is a genetic influence on such an association. Materials and Methods - The near lifetime morbidity for migraine and BTD was examined in two Swedish twin-samples: OCTO-Twin (149 MZ and 202 DZ pairs; 234 men, 468 women; 80 years of age o

Spot Pricing in the Cloud Ecosystem: A Comparative Investigation

Background: Spot pricing is considered as a significant supplement for building a full-fledged market economy for the Cloud ecosystem. However, it seems that both providers and consumers are still hesitating to enter the Cloud spot market. The relevant academic community also has conflicting opinions about Cloud spot pricing in terms of revenue generation. Aim: This work aims to systematically ide