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Background Soft tissue sarcoma (STS) diagnosis is challenging because of a multitude of histopathological subtypes, different genetic characteristics, and frequent intratumoral pleomorphism. One-third of STS metastasize and current risk-stratification is suboptimal, therefore, novel diagnostic and prognostic markers would be clinically valuable. We assessed the diagnostic and prognostic value of

Histidine-rich glycoprotein (HRGP), an abundant heparin-binding protein found in plasma and thrombocytes, exerts antibacterial effects against Gram-positive bacteria (Enterococcus faecalis and Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa). Fluorescence studies and electron microscopy to assess membrane permeation showed that HRGP induces lysis of E

Tumor-associated trypsin inhibitor (TATI) is a marker of mucinous ovarian carcinoma, but it is also widely expressed in other malignant tumors and normal human tissues. Elevated serum concentrations of TATI are of prognostic value in ovarian, kidney, and bladder cancer. Tumor-associated trypsin is co-expressed with TATI in many malignancies and is thought to be involved in tumor invasion. TATI mRN

The association between urinary albumin concentration (UAC) in a morning urine sample and medical risk factors was evaluated in a cross-sectional study of 451 type II (noninsulin-dependent) diabetic patients. The following four groups of patients were created according to their urinary albumin levels: A) normal (less than 12.5 mg/L); B) high normal (12.5-30 mg/L); C) microalbuminuria, ie, incipien

The electrochemical behavior and the electrocatalytic activity for the NADH oxidation at glassy carbon paste electrodes (GCPEs) modified with Meldola Blue (MB) adsorbed onto acidic cc-zirconium phosphate (ZP*) have been investigated. Cyclic voltammetry and rotating disc electrode measurements, performed in Tris buffer solution (pH 7) in absence and in presence of different NADH concentrations, sho

Thiobacillus ferrooxidans and Acidianus brierleyi were capable of oxidizing pure pyrite as well as oxidizing sulfur in coal. First order reactions were assumed in the kinetic analysis performed. For oxidation of pure pyrite the rate constant was higher for A. brierleyi than for T. ferrooxidans. For sulfur removal from coal the values of the rate constants were comparable far the two microorganisms

Background: Only limited information is available on healthy young women's perspective of their own lifestyle behaviours. By lifestyle behaviours, e.g. smoking and physical activity, individuals have the possibility to influence bone mineral density (BMD). The aim of this study was to generate a theoretical model of lifestyle behaviours among young women with different BMD changes. Methods: Dat

Near-infrared dispersed fluorescence measurements of 13 different atomic multiplets of neutral atomic fragments from photon induced neutral dissociation processes in NO are reported. For excitation of the molecules narrow band synchrotron photons of energy 17.2-25.8 eV were used. Neither Rydberg series nor other molecular states in NO known so far can account for the collected data. From ab initio

Objectives To describe the endosonographic image of the anal sphincter 2-7 days after delivery in women who had undergone a primary repair of an obstetric sphincter tear. Methods Forty-eight women who had suffered a third- or fourth-degree sphincter tear at delivery and had undergone primary sphincter repair were examined with endoanal sonography 2-7 days after delivery. A score from 0 to 16 was

Genetic engineering has been used to construct hydrophobically modified fusion proteins of cutinase from Fusarium solani pisi and tryptophan-containing peptides. The aim was to enhance the partitioning of the tagged protein in a novel aqueous two-phase system formed by only one water-soluble polymer. The system was based on a hydrophobically modified random copolymer of ethylene oxide (EO) and pro

By using an experimental setup yielding the acoustical Two-Port properties of earplugs. the attenuation of three fundamentally different types of earplugs is predicted. The setup used is based on molds of the ear canals of a real person, and the Two-Port of each earplug is numerically coupled to an acoustical model of the ear. The predicted attenuation is compared to the subjective attenuation (RE

We investigate spin-dependent transport properties of a two-terminal electron waveguide, attached with a side arm, with Rashba spin-orbit interaction (SOI). The interference between the bound states in the side arm and the continuous states in the straight channel gives rise to broad valleys in the conductance spectrum. At these Fano antiresonances, a large transverse spin polarization can be crea

Popular Abstract in Swedish I avhandlingen behandlas tre texter av den tjeckiske författaren Bohumil Hrabal (1914–1997): ”Mrtvomat” (från 1949), Denna stad är i invånarnas gemensamma vård (från 1967) och ”Legend spelad på strängar spända mellan vaggan och kistan” (från 1968). Alla tre texterna är sammanställda av textsegment valda ur andra författares verk och av fragment av avlyssnade samtal. HraThe main theme of the thesis is an analysis of three texts by the Czech author Bohumil Hrabal (1914 – 1997), namely ’Mrtvomat’ (’Mrtvomat’, 1949), This City is in the Joint Care of Its Inhabitants (Toto mìsto je ve spoleèné péèi obyvatel, 1967), and ’Legend Played on Strings Stretched Between the Cradle and the Coffin’ (’Legenda zahraná na strunách mezi kolébkou a rakví’, 1968). These texts are co

Denna rapport behandlar fuktskador i ett hus uppfört 1973 med platta på mark och flytande golv. Mätningar har genomförts i huset under två år. Syftet var att erhålla mätdata under en lång tidsperiod i en byggnad med klara fukt- och luktproblem. I rapporten diskuteras lämpliga åtgärder för att komma till rätta med problemen.

In this study, we show that distinct compartmentalization patterns of the IL-1 molecules (IL-1alpha and IL-1beta), in the milieu of tumor cells that produce them, differentially affect the malignant process. Active forms of IL-1, namely precursor IL-1alpha (pIL-1alpha), mature IL-1beta (mIL-1beta), and mIL-1beta fused to a signal sequence (ssIL-1beta), were transfected into an established fibrosar