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Early-life disease exposure and its heterogeneous effects on mortality throughout life: Sweden 1905-2016

Exposure to infectious diseases in early life has been linked to increased mortality risk in later life in high-disease settings, such as eighteenth- and nineteenth-century Europe. Less is known about the long-term effects of early-life disease exposure in milder disease environments. This study estimates heterogeneous effects from disease exposure in infancy on later-life mortality in twentieth-c

Assessing urban water demand-side management policies before their implementation : An agent-based model approach

In the context of climate change and increasing water scarcity, adopting water demand-side management (DSM) policies has become necessary. This study advocates for utilizing agent-based modelling (ABM) as a robust simulation tool to assess the impact of nonprice (nudges) and price (changes in increasing block tariff) measures on urban water use. Overcoming challenges posed by insufficient high-qua

Connectivity Constraints Ensuring Continuous Electrodes in Topology Optimization of Electroactive Polymer

Electroactive polymers (EAPs) deform when subject to an electric field, which is generated by two or more electrodes. To ensure proper function of the EAP, these electrodes are connected to a source and they are therefore required to be continuous such that no isolated islands exist. Increasing an EAP’s performance using topology optimization while ensuring electrode connectivity is the goal of th

Minor impact of anastomotic leakage in anterior resection for rectal cancer on long-term male urinary and sexual function

PURPOSE: Anastomotic leakage after anterior resection for rectal cancer induces bowel dysfunction, but the influence on urinary and sexual function is largely unknown. This cross-sectional cohort study evaluated long-term effect of anastomotic leakage on urinary and sexual function in male patients. METHODS: Patients operated with anterior resection for rectal cancer in 15 Swedish hospitals 2007-2

Spatial-temporal differentiation and influencing factors of carbon emission trajectory in Chinese cities - A case study of 247 prefecture-level cities

Cities, where human energy activities and greenhouse gas emissions are concentrated, contribute significantly to alleviating the impacts of global climate change. Utilizing the China Carbon Emissions Accounting Database (CEADs) to provide carbon dioxide emission inventories for urban areas in China at the prefecture level, this study closely examines the historical evolution trajectories of carbon

Electrically active defects in Al2O3-InGaAs MOS stacks at cryogenic temperatures

The effects of defects in In0.47Ga0.53As/Al2O3/Ni metal-oxide-semiconductor (MOS) stacks at cryogenic temperatures are investigated. The MOS stacks exhibit a hysteresis in the capacitance-voltage (CV) curve, both at room temperature and at 100K, indicating the presence of effective charge capture/emission dynamics in the oxide even at cryogenic temperatures. Border traps (BTs) in the Al2O3 close t

Meeting places of the Univer-city : On serendipitous encounters in a growing university area

In this paper we investigate the ways in which a university, taking on the scale of a city of its own, affords meetings for researchers and teachers between disciplines. How does the continuous transformation and expansion of the university’s physical environment affect the everyday lives and serendipitous encounters of the researchers active within it? The aim of the paper is to develop a concept

Role of Iodine-Assisted Aerosol Particle Formation in Antarctica

New particle formation via the ion-mediated sulfuric acid and ammonia molecular clustering mechanism remains the most widely observed and experimentally verified pathway. Recent laboratory and molecular level observations indicate iodine-driven nucleation as a potentially important source of new particles, especially in coastal areas. In this study, we assess the role of iodine species in particle

Provider Perceptions of an Electronic Health Record Prostate Cancer Screening Tool

Objectives We conducted a focus group to assess the attitudes of primary care physicians (PCPs) toward prostate-specific antigen (PSA)-screening algorithms, perceptions of using decision support tools, and features that would make such tools feasible to implement. Methods A multidisciplinary team (primary care, urology, behavioral sciences, bioinformatics) developed the decision support tool that

Professionals’ account-making of institutional care for youths. Intertwined discretionary spaces and blurred collaborative practice

In this article, the account-making of social workers and institutional care staff on locked institutional care for youth is analysed, based on empirical material consisting of 10 interviews with 25 members of the two professions. The study departs from a Swedish context where locked institutional care for youth is mainly provided for individuals who are in compulsory care due to criminality, drug

Reservoir simulation model for the design of irrigation projects

This chapter presents a simulation model for the optimization of a reservoir system that is being developed. Simulation studies were carried out, firstly to determine the best (and by how much) irrigation facilities to provide in the proposed new scheme, and secondly, to see the applicability of simulation in reservoir planning. A computer simulation model using MATLAB has been developed to analyz

Robust Localization of Close-Range Radar Reflections

In order to allow for a computationally efficient estimation of radar reflections, one commonly assumes the reflecting target to be in the far-field of the sensing array, such that the impinging wavefront is modeled as a linear phase-shift along the array. This works well in most radar scenarios, but causes significant performance degradation for close-range radar systems, wherein the curvature of

Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema

Whereas cigarette smoking remains the main risk factor for emphysema, recent studies in β-epithelial Na+ channel-transgenic (βENaC-Tg) mice demonstrated that airway surface dehydration, a key pathophysiological mechanism in cystic fibrosis (CF), caused emphysema in the absence of cigarette smoke exposure. However, the underlying mechanisms remain unknown. The aim of this study was to elucidate mec

Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation

MMP12 is a metalloproteinase implicated in inflammation. To monitor its activity, we synthesized a membrane-targeted reporter (LaRee1) based on Foerster resonance energy transfer (FRET). Unlike existing sensors, LaRee1 detects MMP12 activity by loss of FRET plus internalization of the lipidated fragment. In bronchoalveolar lavages from a mouse model of pulmonary inflammation, LaRee1 detected MMP12

Artificial Intelligence Applications for Sustainable Construction

Artificial Intelligence Applications for Sustainable Construction presents the latest developments in AI and ML technologies applied to real-world civil engineering concerns. With an increasing amount of attention on the environmental impact of every industry, more construction projects are going to require sustainable construction practices. This volume offers research evidence, simulation result

MmWave Massive MIMO Processing in Demanding Environments - An Aircraft Cabin Deployment Study

Massive multiple-input multiple-output (MIMO) technology will continue playing an important role in beyond 5G wireless systems. Fully digital beamforming at the millimeter wave (mmWave) spectrum enables applications that require high data rates and low latency. This paper investigates the development and deployment of mmWave massive MIMO systems in an in-flight cabin environment, from both system

Abrupt termination of the 2019/20 influenza season following preventive measures against COVID-19 in Denmark, Norway and Sweden

BackgroundIn mid-March 2020, a range of public health and social measures (PHSM) against the then new coronavirus disease (COVID-19) were implemented in Denmark, Norway and Sweden.AimWe analysed the development of influenza cases during the implementation of PHSM against SARS-CoV-2 in the Scandinavian countries.MethodBased on the established national laboratory surveillance of influenza, we compar

SARS‐CoV‐2 and pregnancy outcomes under universal and non‐universal testing in Sweden: register‐based nationwide cohort study

ObjectiveTo assess associations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and pregnancy outcomes considering testing policy and test-positivity-to-delivery interval.DesignNationwide cohort study.SettingSweden.PopulationFrom the Pregnancy-Register we identified 88 593 singleton births, 11 March 2020–31 January 2021, linked to data on SARS-CoV-2-positivity from the Pu