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Long-term warming of a subarctic heath decreases soil bacterial community growth but has no effects on its temperature adaptation

We tested whether bacterial communities of subarctic heath soil are adapted to elevated temperature after experimental warming by open-top greenhouses for 7 or 17 years. The long-term warming by 1-2 degrees C significantly decreased bacterial community growth, by 28% and 73% after 7 and 17 years, respectively. The decrease was most likely due to decreased availability of labile substrate under war

Forssman expression on human erythrocytes: biochemical and genetic evidence of a new histo-blood group system

In analogy with histo-blood group A antigen, Forssman (Fs) antigen terminates with alpha 3-N-acetylgalactosamine and can be used by pathogens as a host receptor in many mammals. However, primates including humans lack Fs synthase activity and have naturally occurring Fs antibodies in plasma. We investigated individuals with the enigmatic ABO subgroup A(pae) and found them to be homozygous for comm

A mathematical model of spit growth and barrier elongation: Application to Fire Island Inlet (USA) and Badreveln Spit (Sweden)

A mathematical model of spit growth and barrier elongation adjacent to an inlet (of arbitrary width), supplied by sediment coming from longshore sediment transport, was developed based on the spit growth model proposed by Kraus (1999). The fundamental governing equation is the conservation equation for sand, where the width of the spit is assumed constant during growth. The portion of the longshor

Numerical compression schemes for proteomics mass spectrometry data.

The open XML format mzML, used for representation of mass spectrometry (MS) data, is pivotal for the development of platform-independent MS analysis software. Although conversion from vendor formats to mzML must take place on a platform on which the vendor libraries are available (i.e. Windows), once mzML files have been generated, they can be used on any platform. However, the mzML format has tur

Advancing the global proteome survey platform by using an oriented single chain antibody fragment immobilization approach.

Increasing the understanding of a proteome and how its protein composition is affected by for example different diseases, such as cancer, has the potential to improve strategies for early diagnosis and therapeutics. The Global Proteome Survey or GPS is a method that combines mass spectrometry and affinity enrichment with the use of antibodies. The technology enables profiling of complex proteomes

Multimodal Detection of Iron Oxide Nanoparticles in Rat Lymph Nodes Using Magnetomotive Ultrasound Imaging and Magnetic Resonance Imaging

Detection and removal of sentinel lymph nodes (SLN) is important in the diagnosis and treatment of cancer. The SLN is the first regional lymph node draining the primary tumor, and if the cancer has spread, it is most likely to find metastases in the SLN. In this study, we have for the first time been able to image the very same contrast agent, superparamagnetic iron oxide nanoparticles (SPIO-NPs),

Clinical Correlations With Lewy Body Pathology in LRRK2-Related Parkinson Disease.

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of genetic Parkinson disease (PD) known to date. The clinical features of manifesting LRRK2 mutation carriers are generally indistinguishable from those of patients with sporadic PD. However, some PD cases associated with LRRK2 mutations lack Lewy bodies (LBs), a neuropathological hallmark of PD. We investigated whether th

Normal aging reduces motor synergies in manual pointing

Depending upon its organization, movement variability may reflect poor or flexible control of a motor task. We studied adult age-related differences in the structure of postural variability in manual pointing using the uncontrolled manifold (UCM) method. Participants from 2 age groups (younger: 20-30 years; older: 70-80 years; 12 subjects per group) completed a total of 120 pointing trials to 2 di

Prebiotic and synbiotic effects on rats fed malted barley with selected bacteria strains.

Butyric acid, one of the key products formed when β-glucans are degraded by the microbiota in the colon, has been proposed to be important for colonic health. Glutamine bound to the fibre may have similar effects once it has been liberated from the fibre in the colon. Both β-glucans and glutamine are found in high amounts in malted barley. Lactobacillus rhamnosus together with malt has been shown

Site-level model intercomparison of high latitude and high altitude soil thermal dynamics in tundra and barren landscapes

Modeling soil thermal dynamics at high latitudes and altitudes requires representations of physical processes such as snow insulation, soil freezing and thawing and subsurface conditions like soil water/ice content and soil texture. We have compared six different land models: JSBACH, ORCHIDEE, JULES, COUP, HYBRID8 and LPJ-GUESS, at four different sites with distinct cold region landscape types, to

Exploring the resource logic of student entrepreneurs

This study responds to the call in recent research for comparative studies examining whether student entrepreneurs are different to other kinds of entrepreneurs. Based on institutional theory, the specific question we ask in this study is whether student entrepreneurs who start up their firms in close relation to the university have a different resource logic compared to entrepreneurs who start th

On the Use of Panel Cointegration Tests in Energy Economics

There is a burgeoning literature based on using panel cointegration techniques to study the relationship between energy consumption and GDP. Most panel cointegration tests employed take no cointegration as the null hypothesis. The current paper illustrates how a rejection by such a test cannot be taken as evidence of cointegration for the panel as a whole, a fact that seems to have gone largely un

Multi-century reconstruction of fire activity in Northern European boreal forest suggests differences in regional fire regimes and their sensitivity to climate

Forest fires are one of the main disturbance agents in boreal and temperate ecosystems. To decipher large-scale temporal and spatial patterns of past fire activity in Scandinavia, we analysed the synchronicity of dendrochoronologically reconstructed fire events in a large network of sites (n=62; 3296 samples, 392 individual fire years) covering a wide geographical gradient (56.5-67.0 degrees N and

The long-term outcomes of systemic vasculitis.

Patients with generalized ANCA-associated small vessel vasculitis (AAV) have a very poor outcome if the ANCA-associated vasculitis is not diagnosed, evaluated and treated properly. The introduction of treatment with immunosuppressive therapy has improved patient survival dramatically but with considerable side effects. Besides, almost 50% of surviving patients experience a relapse of vasculitis. S

A systematic review of physical therapy interventions for patients with anorexia and bulemia nervosa

Purpose: The purpose of this systematic review was to summarise the evidence from randomised controlled trials examining the effectiveness of physical therapy compared with care as usual or a wait-list condition on eating pathology and on physiological and psychological parameters in patients with anorexia and bulimia nervosa. Method: EMBASE, PsycINFO, PubMed, Cumulative Index to Nursing and Allie