Objective: In non-muscle-invasive bladder cancer (NMIBC), local recurrence after transurethral resection of the bladder (TURB) is common. Outcomes vary between urological centres, partly due to the sub-optimal surgical technique and insufficient application of measures recommended in the guidelines. This study evaluated early recurrence rates after primary TURB for NMIBC before and after introduci

Autoimmune diseases are characterized by the irregular functioning of the immune system that leads to the loss of tolerance to self-antigens. The underlying nature of autoimmune diseases has led to speculation that the risk of malignancy might be higher or lower in patients with such diseases. However, the rarity and heterogeneity of both autoimmune diseases and malignancies is the main challenge

Binding of 125I-insulin-like growth factor-1 (125I-IGF-1) to rat brain slices was studied after 15 min of two-vessel occlusion ischemia and 1 h to 4 days of recirculation. Ligand binding in the hippocampus increased at 6 h post ischemia in the CA1 and CA3 regions and the dentate gyrus, suggesting that the IGF-1 receptors were up-regulated, while no change was seen in neocortex and striatum. Intrac

The effects of flunarizine, a calcium entry blocker, were evaluated in a long-term survival model of ischemia in rats. One group of animals received the drug orally at 24 and 4 h prior to the insult (40 mg·kg-1·dose-1). Another group was given flunarizine following the insult, intravenously at 5 min (0.1 mg·kg-1), and orally at 8 and 24 h (40 mg·kg-1·dose-1). A third group received the solvent for

This study focuses on the experiential learningtheory as an important teaching method for architecture andurban design students at architecture Dept., Lund University.By applying Kolb' s model - in a course so called ClimateSmart Architecture and Urban Design - , the diverse learningstyles of all learners are incorporated and a step by step coursedesign framework enables studio and seminar designi

Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the

BACKGROUND: Breast cancer (BC) is the most common type of cancer in women worldwide. Post-treatment, patients suffer from side effects and have various rehabilitation needs, which means that individualization is fundamental for optimal rehabilitation. This systematic review (SR) of SRs aims to evaluate the current evidence on rehabilitation interventions in female patients following BC treatment.M

Vår sol är endast en av hundra miljardtals stjärnor i vår Galax. Den är en levande stjärna som ändras från dag till dag. Astronomer studerar solenss yta och dess inne med dedikerade solteleskop.Andra stjärnor därute sitter ofattbart långt från oss, men vi studerar dem ändå. I denna visning upptäcker vi hur stjärnhimlen ändras från en säsong till en annan och vi ser hur stjärnornas rörelse kan hjälOur sun is only one of hundreds of billions in our galaxy. It is a living star and it changes from one day to the next. Astronomers study the solar surface and its interior with dedicated solar telescopes.Other stars are more distant, but we study them also. In this planetarium show we discover how the night sky changes from one season to another and we see how the movement of the stars can lead u

We demonstrate that light charged and extra neutral scalars in the (100-200) GeV mass range pass the potentially dangerous flavor constraints in a particular class of two-Higgs-doublet model which has appropriately suppressed flavor-changing neutral currents at tree level. We study their decay branching ratios into various fermionic final states and comment on the possibility of their detection in

We analyze the scalar sector properties of a general class of two-Higgs-doublet models which has a global U(1) symmetry in the quartic terms. We find constraints on the parameters of the potential from the considerations of unitarity of scattering amplitudes, the global stability of the potential and the p-parameter. We concentrate on the spectrum of the non-standard scalar masses in the decouplin