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State of Knowledge of Thermal Bridges—A Follow up in Sweden and a Review of Recent Research

It is important to minimize transmission heat transfer losses through the building envelope when designing and building energy efficient buildings in heating dominated climates. In such a climate, a large part of the space heating demand is caused by transmission heat transfer losses through the building envelope. Calculations of these losses must be carried out in a correct way to ensure a proper

A Radial Basis Function Method for Approximating the Optimal Event-Based Sampling Policy

In networked control systems it is desirable to have efficient wireless communication (saving energy and bandwidth) while still ensuring good control performance. By abandoning periodic sampling, communication can be made more efficient by sampling and updating the control signal only "when required" based on the system’s behaviour. This is the concept of event-based control. In this work we consi

Marte Meo and Coordination Meetings (MAC): A Systemic School-Based Video feedback Intervention - A Randomised Controlled Trial

Children displaying early disruptive behaviour problems (DBP) in school are at risk for severe long-term problems. This study evaluated and compared a systemic school-based intervention, Marte Meo and Coordination meetings (MAC) with service as usual (SAU) in a randomised controlled trial. The teachers’ and parents’ ratings were collected before and after intervention. Target group were children a

IoT protection through device to cloud synchronization

This paper addresses the problem of protecting distributed IoT units from network based attacks while still having a high level of availability. In particular we suggest a novel method where the IoT device execution state is modeled with a suitable high level application model and where the execution state of the application of the IoT device is 'mirrored' in a cloud executed machine. This machine

PA28αβ overexpression enhances learning and memory of female mice without inducing 20S proteasome activity

BACKGROUND: The proteasome system plays an important role in synaptic plasticity. Induction and maintenance of long term potentiation is directly dependent on selective targeting of proteins for proteasomal degradation. The 20S proteasome activator PA28αβ activates hydrolysis of small nonubiquitinated peptides and possesses protective functions upon oxidative stress and proteinopathy. The effect o

Carvone Contact Allergy in Southern Sweden : A 21-year Retrospective Study

Carvone (l-carvone), a mint flavour in spearmint oil, is considered a mild skin sensitizer. Carvone-sensitization may be linked to oral/perioral signs and oral lichen planus, but studies are sparse. The prevalence of patch test reactions to carvone and relevant findings from the positive group were investigated. Records for patch-tested patients at the Malmö clinic, for the period 1996 to 2016, we

Anabolic and antiresorptive actions of locally delivered bisphosphonates for bone repair

During the last decades, several research groups have used bisphosphonates for local application to counteract secondary bone resorption after bone grafting, to improve implant fixation or to control bone resorption caused by bone morphogenetic proteins (BMps). We focused on zoledronate (a bisphosphonate) due to its greater antiresorptive potential over other bisphosphonates. Recently, it has beco

Problematic gaming and internet use but not gambling may be overrepresented in sexual minorities - A pilot population web survey study

Background: Substance-related addictive disorders are known to be overrepresented in non-heterosexual individuals, but it is largely unknown whether this is also the case for behavioral addictions such as problem gaming and gambling. This study aimed, in a pilot web survey design, to assess whether problematic gambling, gaming and internet use may be more common in individuals with a non-heterosex

Performance of a feature-based algorithm for 3D-3D registration of CT angiography to cone-beam CT for endovascular repair of complex abdominal aortic aneurysms

Background: A crucial step in image fusion for intraoperative guidance during endovascular procedures is the registration of preoperative computed tomography angiography (CTA) with intraoperative Cone Beam CT (CBCT). Automatic tools for image registration facilitate the 3D image guidance workflow. However their performance is not always satisfactory. The aim of this study is to assess the accuracy

HLA and KIR Associations of Cervical Neoplasia

Background: Cervical cancer is the fourth most common cancer in women, and we recently reported human leukocyte antigen (HLA) alleles showing strong associations with cervical neoplasia risk and protection. HLA ligands are recognized by killer immunoglobulin-like receptors (KIRs) expressed on a range of immune cell subsets, governing their proinflammatory activity. We hypothesized that the inherit

miR-483-5p associates with obesity and insulin resistance and independently associates with new onset diabetes mellitus and cardiovascular disease

Our aim was to identify serum microRNAs (miRNAs) in healthy humans which associate with future onset of both diabetes mellitus and cardiovascular disease. We performed global profiling of 753 mature human miRNAs in serum of 12 pilot subjects followed by measurement of 47 consistently expressed miRNAs in fasting serum of 553 healthy subjects from the baseline exam (1991–1994) of the population base

Craniopharyngioma. Morbidity and Structural Changes in the Brain

Hypothalamus (HT) is a brain structure which serves as a coordination center for several vital body functions. Craniopharyngioma (CP) is a pituitary tumor with high morbidity, primarily due to HT lesion. Among important consequences of CP are cognitive dysfunction and intractable weight gain due to HT obesity, resulting in high cardiovascular (CV) risk. A better understanding of the structural bra

Predictive Pressure Control with Multiple Injections

This paper introduces a predictive combustion-engine controller for efficient fulfillment of constraints on peak pressure, exhaust temperature and NO emissions. The controller utilizes a in-cylinder pressure sensor, actuation of multiple fuel injections and numerical optimization. A physical model is used to predict pressure changes due to fuel-injection variation. The predicted pressure is used t

Partially Premixed Combustion (PPC) Stratification Control to Achieve High Engine Efficiency

Partially premixed combustion (PPC) is a hybrid combustion of Homogeneous Charge Compression Ignition (HCCI) and Diesel Combustion (DC), which has a great potential in reducing the fuel consumption. PPC has a longer premixed time than DC but lesser than HCCI. Therefore it is more stratified than HCCI. This paper first presents results on how the stratification using multiple injections and differe

Numerical study of non-reactive tracer transport in a heterogeneous field, with random microscopic dispersivity

One of the most important processes for the groundwater environment is macroscopic dispersion in geological media. In this study, laboratory experiments and numerical simulations are carried out in order to understand the transport of a non-reactive tracer in a heterogeneous porous medium. The method of characteristics and the implicit finite difference method are employed for numerical solutions

Mean arterial pressure during targeted temperature management and renal function after out-of-hospital cardiac arrest

Purpose: This study investigates the association between mean arterial pressure (MAP) and renal function after out-of-hospital cardiac arrest (OHCA). Materials and methods: Post-hoc analysis of 851 comatose OHCA-patients surviving >48 h included in the targeted temperature management (TTM)-trial. Results: Patients were stratified by mean MAP during TTM in the following groups; 80 mmHg (35%). Medi

Aggregation pheromones of Drosophila immigrant, D. phalerata, and D. subobscura

Aggregation pheromones of Drosophila immigrans, D. phalerata and D. subokscura were demonstrated by testing attraction of adult flies to hexane extracts of the flies in a windtunnel bioassay. Extracts of adult males of all species attracted conspecific males and females. However. D. suhobscura flies were attracted only when the extract was applied on food. GC-MS analysis identified (Z)-11-octadece

Food- and density-dependent dispersal : Evidence from a soil collembolan

1. Dispersal in a fungivore species of Collembola, Onychiurus armatus, in a homo- geneous soil was theoretically approached as a deterministic compartmental process, in which the movement of animals between discrete patches could be described by a series of differential equations or by the discrete geometric probability distribution, assuming a constant probability to move from one patch to the ne