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Molecular Mechanisms in Vascular Endothelin B Receptor Up-Regulation

Popular Abstract in Swedish Kardiovaskulära sjukdomar står för en stor del av västvärldens sjuklighet och dödlighet. Dessa sjukdomar kännetecknas av förändringar i det kardiovaskulära systemets funktion, vilket kan leda till ökat blodtryck och förträngning av blodkärlen. Flera olika peptiderga signalsubstanser är involverade i reglering av kärltonus och tillväxt. Av dessa spelar endothelinerna en Cardiovascular diseases are characterized by changes in morphology and function of the blood vessels. Different signalling molecules are involved in these changes. Endothelin-1 (ET-1) is one of the most potent signalling molecules found in man. Its actions are mediated by two receptors, the ETA and the ETB receptors. The ETA receptor is located on the smooth muscle cells and mediates potent contra

Novel Chromatography Matrices for Fast Isolation of Plasmid DNA

As new therapeutic areas in which genetic material is employed, i.e. gene therapy and DNA vaccination, are expanding, a substantial increase in the demand for gene vectors, e.g. plasmid DNA, is foreseen. Chromatography, being a high-resolution method, is considered essential for the purification of gene vectors when high purity is required. Plasmids are large molecules, which cannot penetrate the

No title

The objectives of this dissertation are 1) to describe what child protection services actually do when assessing risk and deciding on interventions, and 2) to analyze this practice in the light of institutional expectations, organizational demands and professional technology. The field work was carried out in two Danish municipal social service agencies. Data consist of records on families subject

Interpretive functions of adjectives in English: A cognitive approach

This book presents a theoretical discussion of the creation of meaning in language, with special focus on the functions that adjectives fulfil in this process. The discussion rests on a dynamic view of meaning and interpretation, according to which there are no fixed linguistics meanings – not even for single lexemes. Instead of symbolising meaning in a more or less static and ‘eternal’ fashion, l

The Rockox' Mables

A number of Roman Marble heads in Swedish Royal possession since the 17th century may be traced back to the collection of the burgomaster Rockox in Antwerpen. Four of these occur in the famous painting by Frans Francken the Younger representing a feast in Nicholaas Rockox' home. Althoug more marble heads to be found in the Stockholm collection may be traced back to Rockox two of the heads in the p

Navagrahas

Based chiefly on textual sources, the article treats of the nine planetary deities of Hinduism, their origin and historical development, major mythology, iconography, rituals, and their relation both to the greater Hindu pantheon and to astrological concepts.

Attentatet på Dramaten. En studie av Alf Sjöbergs uppsättning av Marika Stiernstedts drama. The Outrage at the Royal Dramatic Theatre in Stockholm. A studie of Alf Sjöberg's stageing of Marika Stiernstedt's drama.

Popular Abstract in Swedish Avhandlingen behandlar den svenska författarinnan Marika Stiernstedts drama Attentatet och regissören Alf Sjöbergs uppsättning av det på Dramaten 1944. Produktionsprocessen följs från dramats tillkomst till uppsättningens möte med publiken. Avhandlingen undersöker vad dramat och uppsättningen berättar om tidens oro och om politiska och etiska motsättningar. Fokus liggerThe thesis deals with the Swedish author Marika Stiernstedt's drama The Outrage and Alf Sjöberg's production of it at the Royal Dramatic Theatre in 1944. The production process is followed from the birth of the drama to the production's encounter with the audience. The thesis examines what the drama and the production tell about the unrest of those times and about political and ethical antagonisms