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Acoustophoretic microfluidic chip for sequential elution of surface bound molecules from beads or cells

An acoustophoresis-based microfluidic flow-chip is presented as a novel platform to facilitate analysis of proteins and peptides loosely bound to the surface of beads or cells. The chip allows for direct removal of the background surrounding the beads or cells, followed by sequential treatment and collection of a sequence of up to five different buffer conditions. During this treatment, the beads/

Adsorption of HSA, IgG and laminin-1 on model titania surfaces - effects of glow discharge treatment on competitively adsorbed film composition.

This study investigated the effect of glow discharge treatment of titania surfaces on plasma protein adsorption, by means of ellipsometry and mechanically assisted SDS elution. The adsorption and film elution of three plasma proteins, viz. human serum albumin (HSA), human immunoglobulin G (IgG) and laminin-1, as well as competitive adsorption from a mixture of the three proteins, showed that the a

Parental Awareness of Substance Use Among Adolescents in a Junior High School Sample

There is a lack of studies assessing parental awareness of adolescent alcohol, cigarette, and drug use in the general adolescent population. A total of 1,426 adolescents aged 14 to 16, and their parents, answered questions about adolescent substance use annually during junior high school. Sensitivity for parental report of adolescent substance use was low: 5.6% to 26% for drunkenness, 14.3% to 20.

Dabigatran and its reversal with recombinant factor VIIa and prothrombin complex concentrate: A Sonoclot in vitro study

Objective. Dabigatran is a new oral direct thrombin inhibitor. No specific antidote exists in the event of hemorrhage, but prothrombin complex concentrate (PCC) and recombinant activated factor VII (rFVIIa) are suggested therapies. Sonoclot is a bedside viscoelastic instrument for monitoring the coagulation process in whole blood. The aim of this study was to investigate the effect of dabigatran a

Soil water content and salinity determination using different dielectric methods in saline gypsiferous soil

Abstract in UndeterminedMeasurements of dielectric permittivity and electrical conductivity were taken in a saline gypsiferous soil collected from southern Tunisia. Both time domain reflectometry (TDR) and the new WET sensor based on frequency domain reflectometry (FDR) were used. Seven different moistening solutions were used with electrical conductivities of 0.0053-14 dS m(-1). Different models

Density fitting with auxiliary basis sets from Cholesky decompositions

Recent progress in the use of Cholesky decomposition techniques within the density fitting approximation of two-electron integrals is reviewed with emphasis on the theoretical background. Special attention is paid to the fact that errors due to the density fitting approximation can be controlled by constructing auxiliary basis sets by means of Cholesky decomposition of either the entire or certain

Folkmordet och realpolitik: Svenska delegationen i Konstantinopel rapporterar om folkmordet på armenierna 1915-1923

Artikeln undersöker bakgrunden till varför diskussionen och kravet för ett officiellt erkännande och fördömande av armeniska massakrerna under första världskriget ebbade ut efter krigsslutet. Genom att undersöka de svenska rapporteringarna under och efter kriget belyser artikeln vikten av de politiska och ekonomiska intressen i mörkläggningen av händelserna under världskriget.

Effects of cyanobacteria on fitness components of the herbivore Daphnia

Cyanobacteria are known to negatively affect their herbivores either by being of low nutritional value, by clogging the feeding apparatus or by producing toxins, and specifically, the role of toxins has been debated. Hence, in order to assess to what extent cyanobacterial toxins affect a major herbivore (Daphnia magna) that has had previous experience of cyanobacterial toxins, we conducted a life-

Interacting Effects of Cognitive Load and Adult Age on the Regularity of Whole-Body Motion During Treadmill Walking

We investigated effects of concurrent cognitive task difficulty (n-back) on the regularity of whole-body movements during treadmill walking in women and men from 3 age groups (20-30, 60-70, and 70-80 years old). Using principal component analysis of individual gait patterns, we separated main (regular) from residual (irregular) components of whole-body motion. Proportion of residual variance (RV)

Medial temporal lobe atrophy is underreported and may have important clinical correlates in medical inpatients.

The diagnostic workup in dementia includes brain imaging with reading focussed on signs of cerebrovascular and neurodegenerative disease. We hypothesised that these findings may be underreported in hospital patients, where imaging is often performed to rule out obvious pathology such as haemorrhage. In this study, we review cranial computed tomography (CT) in medical inpatients for white matter ch

Muon reconstruction efficiency and momentum resolution of the ATLAS experiment in proton-proton collisions at root s=7 TeV in 2010

This paper presents a study of the performance of the muon reconstruction in the analysis of proton-proton collisions at root s = 7TeV at the LHC, recorded by the ATLAS detector in 2010. This performance is described in terms of reconstruction and isolation efficiencies and momentum resolutions for different classes of reconstructed muons. The results are obtained from an analysis of J/psi meson a

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The buoyancy of fruits (nutlets in utricles) of the marsh-inhabiting True Fox Sedge (Carex vulpina) was tested experimentally in stagnant water. Only 16 % of the seeds had sunk when the experiment was terminated after 284 days. Seeds did not germinate while floating, but remained fully viable (average 76 % germination for both floating and sunken seeds). For comparison, fruits of the grassland spe

Longitudinal age-and cohort trends in body mass index in Sweden - a 24-year follow-up study

Background: The aim of this longitudinal study was to analyze whether mean Body Mass Index (BMI), assessed at four occasions, changed within different age groups and birth cohorts over time, i.e., between 1980/81 and 2004/05, after adjustment for possible confounders. Methods: A sample of 2728 men and 2770 women aged 16-71 years at study start were randomly drawn from the Swedish Total Population