The preservation of labile biomolecules presents a major challenge in chemistry, and deep eutectic solvents (DESs) have emerged as suitable environments for this purpose. However, how the hydration of DESs impacts the behavior of proteins is often neglected. Here, we demonstrate that the amino acid environment and secondary structure of two proteins (bovine serum albumin and lysozyme) and an antib

This work explores the use of reinforcement learning to design a proactive cloud resource auto-scaler that is able to predict usage across a distributed microservice application. The focus is on serving time-sensitive workloads, e.g., industrial automation, connected XR/VR (eXtended Reality/Virtual Reality), etc., where each job has a deadline and there is some cost associated with missing a deadl

Mitt avhandlingsarbete är ett teoretiskt utforskande av den mellanmänskliga förståelsens tvetydiga roll i praktiskt socialt arbete. Avhandlingen är en sammanläggningsavhandling vilket betyder att den är uppbyggd av flera delstudier och en introducerande tillika sammanfattande kappa. I mina fyra delstudier om ämnena empati, stigmatisering och kamratstöd undersöker jag olika aspekter av mellanmänsklThis thesis aims to explore how phenomenological philosophy may contribute to the conception of interpersonal understanding in the context of social work practice. The thesis consists of an extended introduction and four original papers, investigating modalities of interpersonal understanding in relation to three different subjects, namely empathy, stigmatization, and peer-support. The thesis sets

Acquired haemophilia A (AHA) is a rare bleeding disorder caused by acquired antibodies against coagulation factor VIII. In the Nordic countries, treatment and outcomes have not been studied in recent times. To collect retrospective data on patients diagnosed with AHA in the Nordic countries between 2006 and 2018 and compare demographic data and clinical outcomes with previously published reports,

This chapter describes a preliminary study of sustainable social progress in the Kingdom of Tonga conducted following the 2009 report and recommendations of the Commission on the Measurement of Economic Performance and Social Progress (CMEPSP). Tonga appears to be making reasonable social progress according to GDP, the Human Development Index and Millennium Development Goals metrics. However, clos

Purpose: To investigate the surgical and pharmacological management and outcomes of patients with cataract and concurrent uveitis. Methods: Data from the Swedish National Cataract Register, 2018–2019, were collected and analysed. Uveitic eyes were identified and eyes without uveitis were used as controls. Generalized estimating equations were used to adjust for intra-individual correlation. Result

In the debate on sustainability many scholars are advocating for wider use of social learning models in order to successfully address complex challenges. Waste management is one example of complexity that our societies need to deal with and that increasingly calls for a broader approach, rather than focusing on narrow technical solutions only. This chapter is part of a broader study of limitations

Joint consideration of inventory and shipment decisions is an important aspect of obtaining economically and environmentally sustainable distribution systems. We consider this issue in the context of a one-warehouse-multiple-retailer inventory system with quantity-based shipment consolidation to groups of nonidentical retailers facing Poisson demand. The system is centralized, with free informatio

In this study, a narrative-based language intervention (NBLI) is evaluated in children with HL based on selected narrative outcome measures important for telling and retelling stories. Nine Danish children with slight to severe sensorineural HL in the age range of 4;11–8;8 years participated. The study had a single-arm early efficacy design. The NBLI consisted of four parts: (1) warm-up activity,

This chapter introduces the fundamental topics explored in the anthology; the diverse, and constantly changing, role of transnational feminism as a theoretical and political agenda within social theory more generally, and within gender studies more specifically, and the other role of feminist transnational struggles in the creation of scholarships of hope. The chapters of the anthology are present

Master implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignanci

Multiparameter flow cytometry (MFC) is one of the essential ancillary methods in bone marrow (BM) investigation of patients with cytopenia and suspected myelodysplastic syndrome (MDS). MFC can also be applied in the follow-up of MDS patients undergoing treatment. This document summarizes recommendations from the International/European Leukemia Net Working Group for Flow Cytometry in Myelodysplasti

Sex differences in lifespan are ubiquitous across the tree of life and exhibit broad taxonomic patterns that remain a puzzle, such as males living longer than females in birds and vice versa in mammals. The prevailing unguarded X hypothesis explains sex differences in lifespan by differential expression of recessive mutations on the X or Z chromosome of the heterogametic sex, but has only received

Background: The COVID-19 pandemic has renewed attention to the conflicting demands placed on caregivers worldwide. Nowhere is this more evident than in South Asia, where cultural norms and a scarcity of long-term care facilities have made the home the locus of caregiving for individuals with brain health conditions and disabilities. A hidden cost of this informal arrangement is the burden experien

BACKGROUND: The relation between blood pressure and kidney cancer risk is well established but complex and different study designs have reported discrepant findings on the relative importance of diastolic blood pressure (DBP) and systolic blood pressure (SBP). In this study, we sought to describe the temporal relation between diastolic and SBP with renal cell carcinoma (RCC) risk in detail.METHODS

During 2014–2016, Sweden received almost 300,000 people seeking protection. Politically, this asylum reception has been presented as a “crisis”, and a threat to the welfare system as well as Swedish culture. At the same time, many argue that immigration contributes to society's prosperity, both culturally and economically. The aim of this ethnographic study is to examine how problems are formulate

Flame front structure is one of the most fundamental characteristics and, hence, vital for understanding combustion processes. Measuring flame front structure in turbulent flames usually needs laser-based diagnostic techniques, mostly planar laser-induced fluorescence (PLIF). The equipment of PLIF, burdened with lasers, is often too sophisticated to be configured in harsh environments. Here, to sh

This paper describes the Bárány Society Classification OverSight Committee (COSC) position on Cervical Dizziness, sometimes referred to as Cervical Vertigo. This involved an initial review by a group of experts across a broad range of fields, and then subsequent review by the Bárány Society COSC. Based upon the so far published literature, the Bárány Society COSC takes the view that the evidence s