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Breast tumors from BRCA1 germ line mutation carriers typically exhibit features of the basal-like molecular subtype. However, the specific genes recurrently mutated as a consequence of BRCA1 dysfunction have not been fully elucidated. In this study, we utilized gene expression profiling to molecularly subtype 577 breast tumors, including 72 breast tumors from BRCA1/2 mutation carriers. Focusing on
Burnets were surveyed in 100 semi-natural pastures in the province of Ostergotland, southeastern Sweden. We analysed the presence/absence of burnets in relation to habitat characteristics, and species richness of butterflies and plants. Five species were found (Adscita statices, Zygaena osterodensis, Z. viciae, Z. filipendulae and Z. lonicerae), all occurring in 33%-36% of the localities. Among th
In the aircraft industry maximizing availability is essential. Maintenance schedules must therefore be opportunistic, incorporating preventive maintenance activities within the scheduled as well as the unplanned ones. At the same time, the maintenance contractor should utilize opportunistic maintenance to enable the minimization of the total expected cost to have a functional aircraft engine and t
Kulturartikel om amerikanska nyinspelningar av framförallt franska men också brittiska biosuccéer.
RATIONALE: Thymic Stromal Lymphopoietin (TSLP) is considered a hub cytokine that activates dendritic cells and T-cells producing asthma-like Th(2)-inflammation. Viral stimuli, a major cause of asthma exacerbations, have been shown to induce overexpression of TSLP in asthmatic epithelium. Capsazepine has multiple effects and is of interest because it relaxes human small airways. Here we have explor
We study phase-matching conditions for high-order harmonic generation as well as high-order sum- and difference-frequency mixing processes in strong laser fields, using a graphical approach described in Balcou et al (1997 Phys. Rev. A 55 3204-10). This method is based on the analysis of the different quantum paths that contribute, with different phase properties, to the single-atom response. We pr
The classical connectionist models are not well suited to working with data varying over time. According to this, temporal connectionist models have emerged and constitute a continuously growing research field. In this paper we present a novel supervised recurrent neural network architecture (SARASOM) based on the Associative Self-Organizing Map (A-SOM). The A-SOM is a variant of the Self-Organizi
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Popular Abstract in Swedish Datorgenererade bilder är en viktig del av underhållningsindustrin, som bland annat innefattar spel- och filmindustrin. För att kunna skapa avancerade specialeffekter i filmer samt stora och detaljerade spelvärldar krävs datorprogram som utnyttjar beräkningskraften i dagens datorer på ett effektivt sätt. Bättre och snabbare datorprogram leder ofta till nya användaruppleComputer generated imagery is vital to the entertainment industry in the production of games and films, for example. It is also increasingly important for visualization in design, architecture, engineering, and medicine, to name a few. Improvements to rendering techniques come from a combination of improved algorithms and more powerful hardware. Typically, hardware developments introduce new chall
The low-frequency shot noise properties of two electrostatically coupled semiconductor quantum dot states which are connected to emitter/collector contacts are studied. A master equation approach is used to analyze the bias voltage dependence of the Fano factor as a measure of temporal correlations in tunneling current caused by Pauli’s exclusion principle and the Coulomb interaction. In particula
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