Nitrogenase is the only enzyme that can cleave the strong triple bond in N2, making nitrogen available for biological lifeforms. The active site is a MoFe7S9C cluster (the FeMo cluster) that binds eight electrons and protons during one catalytic cycle, giving rise to eight intermediate states E0–E7. It is experimentally known that N2 binds to the E4 state and that H2 is a compulsory biproduct of t

During the last two decades our understanding of human B cell differentiation has developed considerably. Our understanding of the human B cell compartment has advanced from a point where essentially all assays were based on the presence or not of class-switched antibodies to a level where a substantial diversity is appreciated among the cells involved. Several consecutive transitional stages that

Because Peyer's patches (PP) are the main inductive sites for gut IgA responses we have focused this review on what we know about the function of PP germinal centers (GC).The vast majority of IgA gene sequences in the gut lamina propria (LP) are heavily mutated arguing for an origin in GC. Because PP GC formation is dependent on the presence of CD4 T cells, we speculate that all IgA responses in t

Ett detta kapitel som behandlar sociala rättigheter i ett domstolssammanhang analyseras domstolars betydelsefulla roll när det gäller att uttolka och använda begreppet skälig levnadsnivå, som ett sätt att både omförhandla och utveckla rättigheter.

The intention was at first to design a toy with support and feedback from Brio and so on a visit to their head office in Malmö took place in the beginning of the project. After the visit and further reading about the subject, the project took a different turn. The most interesting aspect of toys became play and the feeling of it; playfulness. The focus hence became on an emotion instead off an

Mutation testing is the state-of-the-art technique for assessing the fault detection capacity of a test suite. Unfortunately, a full mutation analysis is often prohibitively expensive. The CppCheck project for instance, demands a build time of 5.8 min and a test execution time of 17 s on our desktop computer. An unoptimised mutation analysis, for 55,000 generated mutants took 11.8 days in total, o

Using new high-resolution data of CO (2-1), H and H obtained with the Northern Extended Millimeter Array (NOEMA) and the Multi-Unit Spectroscopic Explorer (MUSE) at the Very Large Telescope, we have performed a Toomre Q disc stability analysis and studied star formation, gas depletion times and other environmental parameters on sub-kpc scales within the z ∼0 galaxy SDSS J125013.84+073444.5 (LARS 8

Due to excellent thermal performance and application prospects, nanofluids are attracting many researchers to pay more attention to new types of heat transfer fluids. However, previous studies have focused on the effects of nanofluids on thermophysical properties without considering the limitation of dispersion stability in practical applications. Excellent nanofluid stability is judged with the z

Vilken betydelse har det förvetenskapliga för vetenskapen? Vilka betydelser kan det ha? Ska vi som forskare eftersträva största möjliga vetenskaplighet från början till slut? Annorlunda uttryckt: Ska vi metodiskt trycka bort våra förvetenskapliga impulser? Eller ska vi tvärtom välkomna dem? Att följa varje förvetenskaplig impuls, var vi än befinner oss i forskningsprocessen, skulle förmodligen få

148Gd may contribute to around 50% of the dose from inhalation in case of an accident at the European Spallation Source. Methods for its detection have been developed. They rely on biokinetic models predicting activities of the gamma emitters 146Gd (T1/2= 48.3 d) and 153Gd (T1/2= 240.4 d) as tracers in the lungs, urine, and faeces. The optimal choice of model parameters and associated uncertaintie

Background and objectives: We focus on the linkages between relocation, new forms of partner cohabitation, and retirement. What are the patterns and trajectories of moving in with a partner in retirement? How do older adults experience different transitions, place attachment, and placemaking when they move in with a partner? Research design and methods: In this qualitative study, 50 persons betwee

Background: Dynamic PET imaging studies provide accurate estimates of specific binding, but also measure the relative tracer delivery (R1), which is a proxy for relative cerebral blood flow (rCBF). Recently, studies suggested that R1 obtained from different tracers could be used interchangeably and is irrespective of target tissue. However, the similarities or differences of R1 obtained from diffe

GJ 367 is a bright (V ≈ 10.2) M1 V star that has been recently found to host a transiting ultra-short period sub-Earth on a 7.7 hr orbit. With the aim of improving the planetary mass and radius and unveiling the inner architecture of the system, we performed an intensive radial velocity follow-up campaign with the HARPS spectrograph—collecting 371 high-precision measurements over a baseline of nea

Research in community ecology has tended to focus on trophic interactions (e.g., predation, resource competition) as driving forces of community dynamics, and sexual interactions have often been overlooked. Here we discuss how sexual interactions can affect community dynamics, especially focusing on frequency-dependent dynamics of horizontal communities (i.e., communities of competing species in a

There are different ways of dividing psychology into subdisciplines. The purpose of the present paper is to explore one specific metaperspective on psychological science, seen as having three main branches: person psychology, population psychology, and mechanism psychology, linked to three different levels of research. Person-level research focuses on psychological phenomena as experienced and ena

The rapid development of containerization technology comes with remarkable benefits for developers and operation teams. Container solutions allow building very flexible software infrastructures. Although lots of efforts have been devoted to enhancing containerization security, containerized environments still have a huge attack surface. Completely avoiding severe security issues have so far not be