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Population-based reference values of handgrip strength and functional tests of muscle strength and balance in men aged 70-80 years

With aging, the incidence of falls and fractures increases. There has during the last decades been secular changes in demographics so that the proportion of elderly increases in society. Hence, there is an increasing need for clinicians to be able to make a solid appraisal of the elderly patient's functional capacity, as to identify individuals with an increased risk to fall. If high risk individu

Audio-recorded information to patients considering participation in cancer clinical trials - a randomized study

Background. Patient information in cancer clinical trial is challenging. The value of audio-recording interventions for patients considering participating in clinical trials is unclear. The primary aim of this randomized study was to investigate effects of audio-recorded information on knowledge and understanding in patients considering participation in a clinical trial. Material and methods. Pati

Visualization and manipulation of microRNA in neural cells

microRNA (miRNA) are small non-coding RNA, 21-23 nucleotides long. miRNA provide a new layer of regulatory control over gene expression programs. It is increasingly evident that miRNA are cell type and tissue specific. Many miRNAs have been identified to be highly abundant in certain regions of the brain. It has also been shown that alterations in levels of specific miRNAs have implications in var

Reverse micelles with spines: L-2 phases of surfactant ion-polyion complex salts, n-alcohols and water investigated by rheology, NMR diffusion and SAXS measurements

Homogeneous alcoholic isotropic solutions (L-2 phases) of "complex salts'' of hexadecyltrimethylammonium neutralized by polyacrylate CTAPA(n) (n = 30 or 6000), in the presence of water were examined at 25 degrees C by means of small-angle X-ray scattering (SAXS), rheology and NMR self-diffusion measurements for different n-alcohols (octanol, hexanol and butanol) and at varying water contents. The

Regulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes - A role for the transcription factor NFAT and phosphodiesterase 3B.

The incretin - glucose-dependent insulinotropic polypeptide (GIP) - and the pro-inflammatory cytokine osteopontin are known to have important roles in the regulation of adipose tissue functions. In this work we show that GIP stimulates lipogenesis and osteopontin expression in primary adipocytes. The GIP-induced increase in osteopontin expression was inhibited by the NFAT (the transcription factor

Effects of High Dose Fibrinogen on in vitro Haemodilution with Different Therapeutic Fluids

Background: Therapeutic fluids used in intensive care can have profound effects on coagulation, not only by dilution itself but also by other more complicated interactions. The aim of this in vitro study was to monitor the extent of dilutive coagulopathy induced by the most common therapeutic fluids and to attempt normalization of haemostasis by fibrinogen addition. Methods: 8 patients were re

Hyperfine dependent lifetimes in Mg-like ions

Theoretical investigations of the hyperfine quenching of the two metastable levels 1s(2)2s(2)2p(6)3s3p P-3(0) and P-3(2) have been performed along the magnesium-like iso-electronic sequence ranging from Z = 12 to Z = 31. It is shown that the lifetime of the latter level is sensitive to hyperfine quenching in the beginning of the sequence, but that this sensitivity decreases going to higher Z. It i

Exploring Disaster Recovery: Stakeholder Interfaces, Goals and Interdependencies

Popular Abstract in English Disaster risk management has seen the importance of coordination at various levels of planning and implementation, ranging from preparedness to disaster response, and in planning for long term recovery and sustainable development. There is a need to develop a deeper and analytical understanding of stakeholder coordination for disaster recovery. The thesis is based on caDisaster risk management has seen the importance of coordination at various levels of planning and implementation, ranging from preparedness to disaster response, and in planning for long term recovery and sustainable development. This thesis aims to develop a deeper and analytical understanding of stakeholder coordination for disaster recovery. The thesis is built on case studies from the mega –d

High order splitting methods for analytic semigroups exist

In this paper, we are concerned with the construction and analysis of high order exponential splitting methods for the time integration of abstract evolution equations which are evolved by analytic semigroups. We derive a new class of splitting methods of orders three to fourteen based on complex coefficients. An optimal convergence analysis is presented for the methods when applied to equations o

Radiation treatment monitoring using multimodal functional imaging: PET/CT ((18)F-Fluoromisonidazole & (18)F-Fluorocholine) and DCE-US.

This study aims to assess the effect of radiation treatment on the tumour vasculature and its downstream effects on hypoxia and choline metabolism using a multimodal approach in the murine prostate tumour model CWR22. Functional parameters derived from Positron Emission Tomography (PET)/Computer Tomography (CT) with (18)F-Fluoromisonidazole ((18)F-FMISO) and (18)F-Fluorocholine ((18)F-FCH) as well

Chemometric approach to chromatic spatial variance. Case study: patchiness of the Skyros wall lizard

In this paper, we demonstrate how to take advantage of the large number of spatial samples provided by commercial multispectral RGB imagers. We investigate the possibility to use various multidimensional histograms and probability distributions for decomposition and predictive models. We show how these methods can be used in an example using images of different Skyros wall lizards and demonstrate

Evidence for anomalous water vapor sorption kinetics in cement based materials

We used dynamic sorption balance measurements to evaluate the diffusivity for cement pastes with three different binders (OPC, OPC + 70% slag, OPC + 10% silica fume). The diffusion of water vapor in cement based materials is normally assumed to follow Fick's law of diffusion, but our results clearly show that Ficles law cannot completely describe the sorption process in our materials. In this pape

Gastroesophageal Reflux after Vertical Banded Gastroplasty is Alleviated by Conversion to Gastric Bypass.

BACKGROUND: Conversion operations after vertical banded gastroplasty (VBG) are sometimes performed because of vomiting and/or acid regurgitation. Primary operation with gastric bypass (GBP) is known to reduce gastroesophageal reflux (GERD). Previous studies have not been designed to differentiate between the effects of the altered anatomy and of the ensuing weight loss. No series has reported data

Investigations of initial particle stages during spark discharge

The number of nanoparticle-based products on the market is expected to increase considerably during the coming decades. This forces the industry to have highly meticulous manufacturing of large amounts of nanoparticles using cheap and environmentally friendly methods. For the production of metal nanoparticles spark discharge generation is a promising route to fulfill these demands. The spark disch