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Numerical simulations of NMR relaxation in chalk using local Robin boundary conditions

The interpretation of nuclear magnetic resonance (NMR) data is of interest in a number of fields. In Ögren (2014) local boundary conditions for random walk simulations of NMR relaxation in digital domains were presented. Here, we have applied those boundary conditions to large, three-dimensional (3D) porous media samples. We compared the random walk results with known solutions and then applied th

Laminar burning velocities of methylcyclohexane + air flames at room and elevated temperatures : A comparative study

Laminar burning velocities of methylcyclohexane + air flames were determined using the heat flux method at atmospheric pressure and initial temperatures of 298–400 K. The measurements were performed on two experimental setups at Lund University and Samara National Research University. Our results obtained at the same initial temperatures are in good agreement. Consistency of the measurements perfo

Demographics and The Real Exchange Rate

We develop a two-country, two-sector overlapping generations model to examine the effect of population aging on the real exchange rate (RER). While an older population raises the relative demand for nontradables (a feature of structural transformation) putting upward pressure on relative prices thus appreciating the RER, it also implies a lower real interest rate (distinctive of secular stagnation

Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma

Preventing the immune escape of tumor cells by blocking inhibitory checkpoints, such as the interaction between programmed death ligand-1 (PD-L1) and programmed death-1 (PD-1) receptor, is a powerful anticancer approach. However, many patients do not respond to checkpoint blockade. Tumor PD-L1 expression is a potential efficacy biomarker, but the complex mechanisms underlying its regulation are no

Research for City Practice

CITY KNOW-HOW: Human health and planetary health are both influenced by city lifestyles, city leadership, and city development. For both, worrying trends are leading to increasing concern. It is imperative that both become core foci in urban policy. Changing the trajectory will require concerted action. The journal Cities & Health journal is dedicated to supporting the flow of knowledge, in al

Physiotherapists' experiences of osteoarthritis guidelines in primary health care - an interview study

BACKGROUND: Osteoarthritis is a common joint disease, globally. Guidelines recommend information, exercise and, if needed, weight reduction as core treatment. There is a gap between evidence-based recommended care for osteoarthritis and clinical practice. To increase compliance to guidelines, implementation was conducted. The aim of the study was to explore physiotherapists' experiences of osteoar

Successful competence development for retail professionals : investigation of key mechanisms in informal learning

Purpose – Competence development is a prerequisite for successfully meeting existing and future challenges in the retail sector. However, current human resource development practices are often limited in their scope and offerings. This study sets out to investigate and bring to light informal learning among retail professionals.Design/methodology/approach – This research consists of two explorator

Interfacing antibody-based microarrays and digital holography enables label-free detection for loss of cell volume

We introduce the combination of digital holographic microscopy (DHM) and antibody microarrays as a powerful tool to measure morphological changes in specifically antibody-captured cells. The aim of the study was to develop DHM for analysis of cell death of etoposide-treated suspension cells. Results/methodology: We demonstrate that the cell number, mean area, thickness and volume were noninvasivel

NNLO positivity bounds on chiral perturbation theory for a general number of flavours

We present positivity bounds, derived from the principles of analyticity, unitarity and crossing symmetry, that constrain the low-energy constants of chiral perturbation theory. Bounds are produced for 2, 3 or more flavours in meson-meson scattering with equal meson masses, up to and including next-to-next-to-leading order (NNLO), using the second and higher derivatives of the amplitude. We enhanc

RAF proteins exert both specific and compensatory functions during tumor progression of NRAS driven melanoma.

NRAS and its effector BRAF are frequently mutated in melanoma. Paradoxically, CRAF but not BRAF was shown to be critical for various RAS-driven cancers, raising the question of the role of RAF proteins in NRAS-induced melanoma. Here, using conditional ablation of Raf genes in NRAS-induced mouse melanoma models, we investigate their contribution in tumour progression, from the onset of benign tumou

The Inflammatory Prequel of Pediatric Appendicitis

Background: Appendicitis is the most common disease requiring acute abdominal surgery in children, yet the pathogenesis of appendicitis is not fully understood. It can be challenging to diagnose appendicitis clinically, especially in young children, leading to high rates of initial misdiagnosis. It is not clear why some children are affected by a complicated disease course while others recover spo

Barriers and Enablers for the Adoption of Sustainable Manufacturing by Manufacturing SMEs

Small- and medium-sized enterprises (SMEs) have inherent characteristics, which require specific solutions for improving the sustainability performance of their operations. The purpose of this paper is to increase the knowledge on barriers and enablers for the adoption of sustainable manufacturing by manufacturing SMEs and to provide insights into what enablers can be used to overcome existing bar

From InGaN pyramids to micro-LEDs characterized by cathodoluminescence

We present a study of the optical properties of various steps in the process of fabricating micro light-emitting diodes (μ-LEDs) based on quantum wells embedded in micron-sized InGaN platelets. In this study, we focus on structures for red emission, but the technology is equally suitable for the less technologically challenging blue and green emitting μ-LEDs. The starting point is growth of an InG

Experimental and numerical investigation of outlet guide vane and endwall heat transfer with various inlet flow angles

This paper investigates the heat transfer on the outlet guide vane (OGV) surface and its endwall region. The Reynolds number is fixed at 300,000 and the flow is subsonic. The inlet flow angle is varied from +25°(on-design), to +40°and -25°(off-design). Experiments were conducted in a linear cascade test facility using thermochromic liquid crystal technique. Numerical simulations using RANS were ca

Experimental investigation, modelling and simulation of rate-dependent response of 1-3 ferroelectric composites

Further development and design of piezoelectric composites enhances the improved use of piezoelectric materials and devices by overcoming their brittleness. In order to engineer this class of materials and to predictably simulate its behaviour, a computationally efficient constitutive model is established in this paper. This contribution deals with the development of a model for piezoelectric comp

The Gaia -ESO survey: Mixing processes in low-mass stars traced by lithium abundance in cluster and field stars

Aims. We aim to constrain the mixing processes in low-mass stars by investigating the behaviour of the Li surface abundance after the main sequence. We take advantage of the data from the sixth internal data release of Gaia-ESO, IDR6, and from the Gaia Early Data Release 3, EDR3s. Methods. We selected a sample of main-sequence, sub-giant, and giant stars in which the Li abundance is measured by th