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The equivalence principle comes to school—falling objects and other middle school investigations

Comparing two objects falling together is a small-scale version of Galileo’s classical experiment, demonstrating the equivalence between gravitational and inertial mass. We present here investigations by a group of ten-year-olds, who used iPads to record the drops. The movie recordings were essential in the follow-up discussions, enabling the students to compare the different situations and to dis

Diagnostic Yield and Efficacy of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in Mediastinal Lymphadenopathy.

Introduction: Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) is an emerging minimally invasive option for pathologic examination of intrathoracic lymphadenopathy as well as for staging lung cancer. Objectives: To evaluate the diagnostic yield and possible learning curve effects on diagnostic performance using EBUS-TBNA in mediastinal lymphadenopathy. Methods: A retrospective

Neighbourhood socioeconomic status and coronary heart disease in individuals between 40 and 50 years.

OBJECTIVE: The incidence of myocardial infarction (MI) has decreased in general but not among younger middle-aged adults. We performed a cohort study of the association between neighbourhood socioeconomic status (SES) at the age of 40 and risk of MI before the age of 50 years. METHODS: All individuals in Sweden were included in the year of their 40th birthday, if it occurred between 1998 and 20

Can CSF biomarkers or pre-treatment progression rate predict response to cholinesterase inhibitor treatment in Alzheimer's disease?

OBJECTIVE: The main objective of this study was to investigate possible predictors of response to cholinesterase inhibitor (ChEI) treatment, including pre-treatment progression rates and levels of the cerebrospinal fluid (CSF) biomarkers. A secondary objective was to evaluate whether treatment with ChEI changed progression. METHODS: Out-patient individuals (n = 191) with the clinical diagnosis of

Ethnic differences in anticipated discrimination, generalised trust in other people and self-rated health: a population-based study in Sweden.

This paper investigates the relationship between anticipation that employers may discriminate against certain people (not specified, but not specifically the respondent) according to race, colour of skin, religion or cultural background, and self-rated health, adjusting for social capital in the form of generalised (horizontal) trust in other people. It also investigates ethnic differences in anti

Assessing social responsibility: A quantitative analysis of Appraisal in BP’s and IKEA’s social reports

A growing public awareness of the potential negative impacts of corporate activities on the natural environment and society compels large companies to invest increasing resources in the communication of their responsible conduct. This article employs Appraisal theory in a comparative analysis of BP’s and IKEA’s 2009 social reports, each company’s record of their non-financial performance. The main

The chimney graft: a technique for preserving or rescuing aortic branch vessels in stent-graft sealing zones.

PURPOSE: To report an alternative to the fenestrated stent-graft for preserving blood flow to side branches in the sealing zones of aortic stent-grafts. TECHNIQUE: A covered stent is deployed parallel to the main aortic stent-graft, protruding somewhat proximally, like a chimney, to preserve flow to a vital side branch covered by the aortic stent-graft. Use of a chimney graft makes it possible to

Comparative outcome of double lung transplantation using conventional donor lungs and non-acceptable donor lungs reconditioned ex vivo.

A method to evaluate and recondition lungs ex vivo has been tested on donor lungs that have been rejected for transplantation. In the present paper, we compare early postoperative course between the six patients who received reconditioned lungs and the patients who received conventional donor lungs during the same period of time. During 2006 and 2007, a total of 21 patients underwent double sequen

Elevated Plasma Homocysteine Level Is Not Primarily Related to Alzheimer's Disease.

Background: A moderate elevation of plasma total homocysteine (tHcy) is considered a potential risk factor for Alzheimer's disease (AD). Methods: We have investigated the main determinants (age, renal impairment, cobalamin/folate status and the presence of vascular disease) of plasma tHcy in 326 patients with AD, and also in 281 patients with mild cognitive impairment (MCI), since about half of th

δ' potential arising in exterior complex scaling

In the method of exterior complex scaling the coordinates of the Hamilton operator are scaled by a constant factor starting at a radius R≠0. We show that this procedure induces a singularity in the kinetic-energy term which must be interpreted as the derivative of a δ function.

Pole walking for patients with breast cancer-related arm lymphedema.

Arm lymphedema is a well-known side effect of breast cancer treatment. Studies of the effect of physical exercise on arm lymphedema are very rare. The purpose of this study was to investigate the influence of pole walking on breast cancer-related arm lymphedema when using a compression sleeve. Twenty-six women with unilateral arm lymphedema took part in a clinical study of pole walking on one occa

Adrenergic and cardiac dysfunction in primary hyperparathyroidism.

Objective: Primary hyperparathyroidism (PHPT) is associated with cardiovascular morbidity and premature death but the underlying mechanisms are incompletely understood. The aim of this study was to investigate if adrenergic dysfunction may be a contributing factor. Patients and methods: Forty-nine patients with mild PHPT (serum calcium 2.7 ± 0.1 mmol/L) and 48 control subjects, matched for age an

RNAi screen identifies MAPK14 as a druggable suppressor of human hematopoietic stem cell expansion.

We report on a forward RNAi screen in primary human hematopoietic stem and progenitor cells, using pooled lentiviral shRNA libraries deconvoluted by next generation sequencing. We identify MAPK14/p38α as a modulator of ex vivo stem cell proliferation and show that pharmacological inhibition of p38 dramatically enhances the stem cell activity of cultured umbilical cord blood derived hematopoietic c

Quantifying the absorption and reduced scattering coefficients of tissuelike turbid media over a broad spectral range with noncontact Fourier-transform hyperspectral imaging

Absorption (mu (a)) and reduced scattering (mu (s)') spectra of turbid media were quanti fied with a noncontact imaging approach based on a Fourier-transform interferometric imaging system (FTIIS). The FTIIS was used to collect hyperspectral images of the steady-state diffuse reflectance from turbid media. Spatially resolved reflectance data from Monte Carlo simulations were fitted to the recorded

A systematic approach to robust preconditioning for gradient-based inverse scattering algorithms

This paper presents a systematic approach to robust preconditioning for gradient-based nonlinear inverse scattering algorithms. In particular, one- and two-dimensional inverse problems are considered where the permittivity and conductivity profiles are unknown and the input data consist of the scattered field over a certain bandwidth. A time-domain least-squares formulation is employed and the inv