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Repetitive DNA in search of a function - a study of telomeric and centromeric sequences in Chironomus

Repetitive DNA is quantitatively the main component of telomeres and centromeres, structures responsible for maintenance of the eukaryotic chromosome. The telomere is the specialized nucleoprotein complex that terminates linear chromosomes. In most species the DNA component consists of short repeats which are generated by the enzyme complex telomerase. However, there are important exceptions such

Molecularly imprinted polymers

Molecularly imprinted polymers (MIPs) are man-made polymeric materials with molecular recognition abilities. The polymers mimic the molecular recognition of natural molecular recognition elements, such as receptors and antibodies, by binding target molecules in a highly selective manner. The interactions between MIPs and their targets are of non-covalent or covalent nature, or a mixture thereof. F

Dynamics of Ca2 handling in vascular smooth muscle

Popular Abstract in Swedish Glatt muskulatur är nödvändig för funktionen hos de flesta inre organ såsom blodkärl, tarmar, gallblåsa, livmoder, urin och luftvägar. I artärer bildar glatta muskelceller ett cirkulärt lager, som skiljs från blodet genom ett tunt endotelcellslager. Muskelns främsta uppgift är att kontrollera blodkärlens diameter, och därmed blodflödet till de vävnader som de försörjer.Intracellular Ca2+ is a key regulator of vascular contractility, and thereby of blood perfusion and pressure. Ca2+ signals are essential also for cell migration, proliferation and regulation of numerous enzymes. Besides producing vascular contraction smooth muscle cells may also modulate to a synthetic phenotype and proliferate as an initial stage in the atherosclerotic process. In this work we sh

Motståndets berättelser. Elin Wägner, Anna Lenah Elgström, Marika Stiernstedt och första världskriget

War criticism is not just expressed in journalistic and academic writing or in political speeches, but also in literature, such as in novels and short stories. This dissertation analyzes how war criticism is formulated in Swedish fiction written during the First World War (1914–1918). The study combines perspectives from rhetorical, narrative and sociological theory and focuses on how writers resi