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Background: The concerted effects of changes in gene expression due to changes in the environment are ultimately reflected in the metabolome. Dynamics of metabolite concentrations under a certain condition can therefore give a description of the cellular state with a high degree of functional information. We used this potential to evaluate the metabolic status of two recombinant strains of Sacchar

ASHEIM B. T., LAWTON SMITH H. and OUGHTON C. Regional innovation systems: theory, empirics and policy, Regional Studies. Interest in regional innovation systems has grown significantly over the past three decades driven partly by advances in theoretical analysis, partly by the growing interest in innovation as a source of competitive advantage, and partly by the need for new policies to address re

Esters of phosphoric acid constitute a sizable fraction of the total phosphorus supply in the environment and thus play an important role in the global phosphorus cycle. Enzymatic hydrolysis of these esters to produce orthophosphate is often a required reaction preceding phosphorus uptake by plants and microorganisms. Generally, adsorption to environmental particles is assumed to limit this proces

Produktion av biogas från gödsel har i flera studier visat sig leda till stora positiva miljöeffekter, i synnerhet vad gäller emissioner av växthusgaser, jämfört med andra förnybara energibärare. Skälet är att produktionen av biogas, utöver att ersätta fossila bränslen, också ger en minskad miljöpåverkan från konventionell hantering av stallgödsel. Trots dessa positiva miljöeffekter utnyttjas dock

Background: The influence of variants at the 9p21 locus on melanoma risk has been reported through investigation of CDKN2A variants through candidate gene approach as well as by genome wide association studies (GWAS). Methods: In the present study we genotyped, 25 SNPs that tag 273 variants on chromosome 9p21 in 837 melanoma cases and 1154 controls from Spain. Ten SNPs were selected based on previ

Syftet med denna studie är att utifrån mitt empiriska material kartlägga och beskriva hur föräldrar till barn intagna på särskilda ungdomshemmen tolkar, definierar och upplever ett behandlingsprojekt, som involverade olika myndigheter, benämnt Motverka Våld och Gäng. Dessutom uppmärksammas hur de anställda samordnarna uppfattades och kategoriserades av föräldrarna. ”Föräldrar” blir i undersökninThe aim of this study is to analyze how mothers with children placed in Swedish juvenile homes interpret, define and perceive, on the one hand, the project “Motverka Våld och Gäng” meaning “Counteract Violence and Gangs”, and on the other hand the role of the Coordinators employed in this project. The mothers who were interviewed spoke about some Coordinators that they appreciated. They then pain

Bet-hedging theory addresses how individuals should optimize fitness in varying and unpredictable environments by sacrificing mean fitness to decrease variation in fitness. So far, three main bet-hedging strategies have been described: conservative bet-hedging (play it safe), diversified bet-hedging (don't put all eggs in one basket) and adaptive coin flipping (choose a strategy at random from a f

Predator-prey interaction strengths in variable environments constitute a fundamental link to the understanding of aquatic ecosystem responses to environmental change. The present study investigates the effects of visibility conditions and prey fish density on predation rates of visually oriented piscivorous Eurasian perch Perca fluviatilis L. This was done in outdoor mesocosm (16 m(2)) experiment

The two-body photodisintegration of He-3 has been investigated using tagged photons with energies from 14-31 MeV at MAX-lab in Lund, Sweden. The two-body breakup channel was unambiguously identified by the (nonsimultaneous) detection of both protons and deuterons. This approach was made feasible by the overdetermined kinematic situation afforded by the tagged-photon technique. Proton-and deuteron-

We present results of a resonant photoemission study of (Zn,Co)O films with Co content between 2% and 7%. The films were grown by Atomic Layer Deposition (ALD) at low temperature of 160 degrees C and show fully paramagnetic behavior. The Co ions are uniformly distributed in the ZnO matrix and are free of foreign phases and metal accumulations as indicated by TEM data. The electronic structure of (

We have investigated the Ash Shutbah circular structure in central Saudi Arabia (21 degrees 37N 45 degrees 39E) using satellite imagery, field mapping, thin-section petrography, and X-ray diffraction of collected samples. The approximately 2.1km sized structure located in flat-lying Jurassic Tuwaiq Mountain Limestone has been nearly peneplained by erosional processes. Satellite and structural data

In this paper we consider the problem of a firm that faces a stochastic (Poisson) demand and must replenish from a market in which prices fluctuate, such as a commodity market. We describe the price evolution as a continuous stochastic process and we focus on commonly used processes suggested by the financial literature, such as the geometric Brownian motion and the Ornstein-Uhlenbeck process. It

Popular Abstract in Swedish barnet. Förekomsten av graviditetsdiabetes ökar stadigt, främst pga. ökad vikt hos mamman. Syftet med min avhandling var att undersöka både den kort och långsiktiga risken för hjärtpåverkan hos avkomman till kvinnor med diabetes under graviditeten, undersöka om Apgar-poäng kan användas som mått på förlossningsvården, samt jämföra Apgar-poäng hos nyfödda beroende på om mMaternal diabetes mellitus (DM) during pregnancy has detrimental health impacts on both the mother and fetus, and include increased risks of cardiac malformations, cesarean section (CS), and asphyxia. The aim of the thesis was to investigate short and long term cardiac effects after fetal exposure to DM, investigate the ability of a 5 minute Apgar score as a marker for obstetrical care, investigat

Popular Abstract in Swedish Huntingtons sjukdom (HS) är en ärftlig hjärnsjukdom utan botemedel. Den orsakas av en mutation i en gen som kallas huntingtin. Den klassas som en s.k. neurodegenerativ sjukdom, där man ser en förlust av neuroner i delar av hjärnan som kontrollerar kroppsrörelser. Detta resulterar i dansliknande rörelser (chorea) och det är även därför som HS ibland kallas för danssjukanHuntington’s disease (HD) is a fatal, hereditary disease for which there is no cure. It is caused by a mutation in a gene called huntingtin. HD is a so-called neurodegenerative disease, where there is a loss of neurons in areas of the brain that control body movements. This results in uncontrolled dance-like movements (chorea). Traditionally, research on HD has focused round the brain and what is

Objectives To perform fine mapping of the PXK locus associated with systemic lupus erythematosus (SLE) and study functional effects that lead to susceptibility to the disease. Methods Linkage disequilibrium (LD) mapping was conducted by using 1251 SNPs (single nucleotide polymorphism) covering a 862 kb genomic region on 3p14.3 comprising the PXK locus in 1467 SLE patients and 2377 controls of Euro

The laws of fluid dynamics govern vortex ring formation and precede cardiac development by billions of years, suggesting that diastolic vortex ring formation is instrumental in defining the shape of the heart. Using novel and validated magnetic resonance imaging measurements, we show that the healthy left ventricle moves in tandem with the expanding vortex ring, indicating that cardiac form and fu

Animal flight performance has been studied using models developed for man-made aircraft. For an aeroplane with fixed wings, the energetic cost as a function of flight speed can be expressed in terms of weight, wing span, wing area and body area, where more details are included in proportionality coefficients. Flying animals flap their wings to produce thrust. Adopting the fixed wing flight model i

Monitoring of glucose in subcutaneous and brain striatum have been extensively studied in the past. While biocompatibility was one of the limitations, others included the messy measuring equipments preclude monitoring in a complex environment. This study tried to establish an amperometric measurement of glucose in pre- and post-insulin-administration on diabetic and hyperglycemia rats via wireless

Two compounds, [Cu5I5](SNC5H4)2 [i] and [Cu3I3](SNC5H4)2 [ii], were synthesized under hydrothermal conditions and the crystal structures were solved. Both compounds crystallized in space group 141/a. The iodide and the sulphur from mercaptopyridine are connected to copper atom, giving the copper atoms tetrahedral coordination geometry. The pyridine end of the organic moiety is non-bonding and fill