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Multilevel analysis of birthplace effect on the proportion of C-Section in Colombia"

Objectives: To determine the general contextual effect of the department in the variation of Cesarean section in Colombia in 2016, and their individual and contextual related factors.Methods: Cross-sectional study based on a birth cohort. We used the birth certificate database from January 1 to December 31, 2016. Three multilevel logistic models were constructed. Pregnant women were set at the fir

Rotation cropping and organic fertilizer jointly promote soil health and crop production

Identifying field management practices to promote crop production, while conserving soil health is essential to maintain long-term food production in a changing world. Also, providing experimental evidence to support the use of traditional agricultural practices is necessary to secure sustainable agriculture. Here, we conducted a long-term 12-year experiment to investigate the impact of different

1500-talets Lund ur ett nytt perspektiv

I det omfattande geografiska verket Civitates orbis terrarum från slutet av 1500-talet avbildas bland ett stort antal europeiska städer även ett fåtal nordiska, däribland Lund i form av ett kopparstick av Franz Hogenberg, en bild som har diskuterats tidigare, ofta tillsammans med en nära samtida kartskiss i Anders Vedels samlingar. Författaren gör här en djupanalys och nytolkning av denna bild, oc

Tower Houses in Medieval Scanian Towns

Towers in medieval towns is something normally connected to southern Europe. In Scandinavia, towers are seen as something belonging to castles and residences in the countryside, not to urban milieus. However, they are to be found even in Scandinavian towns. In this paper the existence of private urban tower houses in medieval Scania will be presented and discussed, and a hypothesis about a previou

Head-to-head comparison of a Si-photomultiplier-based and a conventional photomultiplier-based PET-CT system

Background: A novel generation of PET scanners based on silicon (Si)-photomultiplier (PM) technology has recently been introduced. Concurrently, there has been development of new reconstruction methods aimed at increasing the detectability of small lesions without increasing image noise. The combination of new detector technologies and new reconstruction algorithms has been found to increase image

Strategies for Empowering activities in Everyday life (SEE 1.0) : study protocol for a feasibility study of an Internet-based occupational therapy intervention for people with stroke

Background: Rehabilitation after stroke seldom focuses on needs related to an active everyday life and the process of change that people must undergo to adapt to an altered capacity and life situation. In particular, occupational therapy in the late phase needs to support clients in adopting sustainable self-initiated management strategies to regain daily activities and an active everyday life. To

Clinical characteristics and histopathological patterns of hodgkin lymphoma and treatment outcomes at a tertiary cancer center in ethiopia

PURPOSE In developing countries, Hodgkin lymphoma (HL) affects the young population. In Ethiopia, nearly 70% of the population are, 35 years of age. Therefore, this study aimed to elucidate the age distribution, histopathologic patterns, clinical characteristics and treatment outcomes of HL in Ethiopia. MATERIALS AND METHODS Data from clinical records of 133 consecutive patients with HL between 20

Apalutamide in Patients With Metastatic Castration-Sensitive Prostate Cancer : Final Survival Analysis of the Randomized, Double-Blind, Phase III TITAN Study

PURPOSE: The first interim analysis of the phase III, randomized, placebo-controlled TITAN study showed that apalutamide significantly improved overall survival (OS) and radiographic progression-free survival in patients with metastatic castration-sensitive prostate cancer (mCSPC) receiving ongoing androgen deprivation therapy (ADT). Herein, we report final efficacy and safety results after unblin

Corticotroph Aggressive Pituitary Tumors and Carcinomas Frequently Harbor ATRX Mutations

Context: Aggressive pituitary tumors (APTs) are characterized by unusually rapid growth and lack of response to standard treatment. About 1% to 2% develop metastases being classified as pituitary carcinomas (PCs). For unknown reasons, the corticotroph tumors are overrepresented among APTs and PCs. Mutations in the alpha thalassemia/mental retardation syndrome X-linked (ATRX) gene, regulating chrom

11C-Metomidate PET/CT Detected Multiple Ectopic Adrenal Rest Tumors in a Woman with Congenital Adrenal Hyperplasia

Context: Women with congenital adrenal hyperplasia (CAH) may present with androgen excess that is difficult to control with conventional suppressive doses of glucocorticoids. Clinical management is challenging, and the woman is at great risk of developing steroid-induced complications. Patients and Methods: A 32-year-old woman with salt-wasting CAH due to 21-hydroxylase deficiency underwent right-

Advances in Type 1 Diabetes Prediction Using Islet Autoantibodies : Beyond a Simple Count

Islet autoantibodies are key markers for the diagnosis of type 1 diabetes. Since their discovery, they have also been recognized for their potential to identify at-risk individuals prior to symptoms. To date, risk prediction using autoantibodies has been based on autoantibody number; it has been robustly shown that nearly all multiple-autoantibody-positive individuals will progress to clinical dis

Impact of glucocorticoids on the incidence of lupus-related major organ damage : A systematic literature review and meta-regression analysis of longitudinal observational studies

Objective In systemic lupus erythematosus (SLE), disease activity and glucocorticoid (GC) exposure are known to contribute to irreversible organ damage. We aimed to examine the association between GC exposure and organ damage occurrence. Methods We conducted a literature search (PubMed (Medline), Embase and Cochrane January 1966-October 2021). We identified original longitudinal observational stud