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Complement C3 and incident hospitalization due to chronic kidney disease : a population-based cohort study

BACKGROUND: Circulating C3 has been associated with diabetes and hypertension, which are the leading causes of chronic kidney disease (CKD). C3 activation is considered to contribute to several renal diseases. Here we examined whether elevated C3 concentration is associated with hospitalization due to CKD in the general population, and whether this relationship is mediated by factors such as diabe

Batch adjustment by reference alignment (BARA) : Improved prediction performance in biological test sets with batch effects

Many biological data acquisition platforms suffer from inadvertent inclusion of biologically irrelevant variance in analyzed data, collectively termed batch effects. Batch effects can lead to difficulties in downstream analysis by lowering the power to detect biologically interesting differences and can in certain instances lead to false discoveries. They are especially troublesome in predictive m

Att göra hem : En studie av unga mäns boende och konsumtion på 2000-talet

“Home” has become a commercialised place in contemporary Sweden. As both cause and ef- fect of this development, the Swedish market for furniture and interior decoration has grown significantly during the last twenty years. Retailers, television shows and magazines have con- tributed to a steadily progressing market, where consumers shop for the latest in furniture as well as the latest ideas and

Energy Efficiency in Tenant-Owners' Residences : The Process of Going from Objective to Implementation

This article focuses on how Sweden's largest tenant-owners' organization, HSB, deals with energy efficiency. The aim is to examine HSB's energy goals, how they are determined and how they should be implemented at four levels: the national association, the regional office, the local housing co-operatives and the tenant-owners. Representatives of all four levels were interviewed. Achieving energy go

Environmental consciousness

Achieving ambitious international energy-saving targets calls for more powerful instruments and will entail changes both in society as a whole and for individual actors. Besides developing increasingly efficient technology, the field of energy behaviour holds the greatest potential of energy conservation. This contribution considers households and how technology and design can support them in both

Between natural monopoly and third party access - Swedish district heating market in transition

The Swedish energy sector has gone through a number of major changes over the last 15 years. In 1996, the electricity market was deregulated, and at the same time the prerequisites for district heating were changed, as the heat was now supposed to be sold at market price rather than self-cost price. In this chapter we analyse the process of market transformation in the district heating sector foll

GW approximations and vertex corrections on the Keldysh time-loop contour : Application for model systems at equilibrium

We study the effects of self-consistency and vertex corrections on different GW-based approximations for model systems of interacting electrons. For dealing with the most general case, we use the Keldysh time-loop contour formalism to evaluate the single-particle Green's functions. We provide the formal extension of Hedin's GW equations for the Green's function in the Keldysh formalism. We show an

Proinflammatory and amyloidogenic S100A9 induced by traumatic brain injury in mouse model

Traumatic brain injury (TBI) represents a significant risk factor for development of neurodegenerative diseases such as Alzheimer's and Parkinson's. The S100A9-driven amyloid-neuroinflammatory cascade occurring during primary and secondary TBI events can serve as a mechanistic link between TBI and Alzheimer's as demonstrated recently in the human brain tissues. Here by using immunohistochemistry i

Prevalence of sustained remission in rheumatoid arthritis: impact of criteria sets and disease duration, a Nationwide Study in Sweden

Objectives The aims of this national study in Sweden of patients with RA were to: examine the prevalence of sustained remission (SR), that is, remission lasting for at least 6 months; compare the prevalence of SR in patients with early RA and established RA; study the timing of onset of and time spent in SR; and study possible predictors of SR. Methods Adult patients with RA included in the Swedis

Systemic Risk and Centrality Revisited: The Role of Interactions

We suggest that banks contribute extensively to systemic risk only if they are both "risky" and centrally placed in the financial network. To calculate systemic risk we apply the CoVaR measure of Adrian and Brunnermeier (2016) and measure centrality using detailed US loan syndication data. In agreement with our conjecture our main finding is that centrality is an important determinant of systemic

Short-Term Spatial and Temporal Carbonate Chemistry Variability in Two Contrasting Seagrass Meadows : Implications for pH Buffering Capacities

It has been hypothesized that highly productive coastal ecosystems, such as seagrass meadows, could lead to the establishment of ocean acidification (OA) refugia, or areas of elevated pH and aragonite saturation state (Ωa) compared to source seawater. However, seagrass ecosystems experience extreme variability in carbonate chemistry across short temporal and small spatial scales, which could impac

"Otrygghet" i politisk kommunikation : En begreppslig jämförelse och analys av 1970 and 2010-talen

This paper examines usage, function and meaning of the Swedish concept of ”otrygghet” (approx.: unsafety or insecurity) in political documents from two periods: 1970s and 2010s. Departing from a theoretical framework inspired by conceptual historian Reinhart Koselleck, this paper synchronically compares documents from Sweden’s two largest parties (Socialdemokraterna and Moderaterna), and diachroni

Changes in hospital costs for an appendectomy : 1955, 1965, and 1975

A reduction in the number of postoperative bed days for patients who underwent appendectomy led to a study of changes in hospital costs of appendectomies for the years 1955, and 1965, and 1975. No significant changes were found in the total hospital costs. However, the postoperative costs decreased by 36 percent from 1955 to 1975 due to a decrease in the mean duration of hospital stay. During the