Objective To investigate the congenital heart disease (CHD) found in association with an increased nuchal translucency (NT) at 11 - 14 weeks of gestation in chromosomally normal and abnormal fetuses. Methods Patients referred from January 1998 until May 2007 with an increased NT (>= 95th percentile) where CHD was diagnosed were included. Chromosome analysis, fetal and postnatal echocardiography we

Objective. Recent work has shown that several soluble biomarkers, detectable in peripheral blood, synovial fluid, and/or urine, reflect remodeling of joint tissues and may therefore constitute outcome measures that reflect joint damage. Consequently, it is now desirable to begin the process of developing criteria for validation of a soluble biomarker as an outcome measure reflecting structural dam

The solution structures and dynamic behaviour of [Rh6(CO)14(µ-PX)][PX = diphenyl(2-pyridyl)phosphine, (PN); diphenyl(2-thienyl)phosphine, (PS); diphenyl(vinyl)phosphine, (PV)] have been studied by multinuclear NMR and the X-ray structure of [Rh6(CO)14(µ,3-PV)] is reported. In solution, the above clusters undergo a variety of localised CO-exchanges and the mechanisms of these are discussed. The PV

BACKGROUND: We studied the effect on skin papillomas of topical application of a complex of α-lactalbumin and oleic acid (often referred to as human α-lactalbumin made lethal to tumor cells [HAMLET]) to establish proof of the principle that α-lactalbumin-oleic acid kills transformed cells but not healthy, differentiated cells. METHODS: Forty patients with cutaneous papillomas that were resistant t

Objectives: To investigate whether amniotic fluid concentrations of non protein bound iron (NPBI) vary with growth in healthy fetuses and also offer a reference curve in the second trimester of pregnancy. Design and methods: Amniotic fluid concentrations of NPBI were measured by HPLC in 118 women with physiological singleton pregnancies, who underwent amniocentesis for fetal karyotype between week

By use of time-resolved spectroscopy it is possible to separate light scattering effects from chemical absorption effects in samples. In the study of propagation of short light pulses in turbid samples the reduced scattering coefficient and the absorption coefficient are usually obtained by fitting diffusion or Monte Carlo models to the measured data by use of numerical optimization techniques. In

In this project a technique to optically measure the temperature is evaluated. The measurement is to be performed through optical fibres during photodynamic laser treatments or laser thermo therapy of malignant tumours. For this technique Cr3+-doped crystals were used. The lifetime of the ions' fluorescence were measured, since the fluorescence is strongly temperature dependent. A piece of a cryst

AIMS/HYPOTHESIS: Glucose-stimulated insulin secretion is dependent on the electrical activity of beta cells; hence, genes encoding beta cell ion channels are potential candidate genes for type 2 diabetes. The gene encoding the voltage-dependent Ca(2+) channel Ca(V)2.3 (CACNA1E), telomeric to a region that has shown suggestive linkage to type 2 diabetes (1q21-q25), has been ascribed a role for seco

Two models for exact classical trajectories in the field of an isotropic potential are investigated for the purpose of semiclassical linebroadening calculations. The first directly uses the exact solution of the classical equation of motion. The second starts from the equation of motion and computes the trajectory by numerical solution of the differential equations. In the framework of both models

Background: Recent studies on the pathophysiology of heart failure indicate the role of neurohormones and immune and inflammatory processes as potential mechanisms involved in the pathogenesis and clinical course of chronic heart failure (CHF). Aim: To analyse the relationship between concentrations of brain natriuretic peptide (BNP), endothelin-1 (ET-1), inflammatory cytokines (TNF-alpha, IL-6) a

An enrichment technique was used to isolate 11 di-, tri-, and tetra microsatellites for the parasitic fly Philornis downsi (Diptera: Muscidae). These loci were polymerase chain reaction amplified in singleplexes or two-plexes for P. downsi. The loci showed low to moderate polymorphism, exhibited between three and four alleles, and observed heterozygosity ranged from 0.05 to 0.86. These new markers

Digital elevation models (DEMs) can be captured and analysed by various methods. Elevation capturing with RTK-GPS and airborne laser scanning is presented and evaluated in terms of height accuracy of raw data and interpolated DEMs for study sites in Sweden and Germany. Applications for precision agriculture are based on the connection of land surface and the movement of water in the landscape. Thr

In mature seeds of Brassica napus three major and three minor myrosinase isoenzymes were identified earlier. These myrosinases are known to be encoded by at least two different families of myrosinase genes, denoted MA and MB. In the work described in this paper the presence of different myrosinase isoenzymes in embryos, seedlings, and vegetative mature tissues of B. napus was studied and related t

During recent decades the incidence of testicular cancer (TC) has increased rapidly around the world. Associated exogenous etiological factors might therefore be identifiable. We performed a case-control study nested within Finnish, Swedish and Icelandic maternity cohorts exploiting early pregnancy serum samples to evaluate the role of congenital or neonatal infections with Epstein-Barr virus (EBV

A new electrochemical reactor, three-phase three-dimensional electrode reactor, was designed and used to investigate the removal of formic acid from simulated wastewater. The experimental results were assessed in term of Chemical Oxygen Demand (COD) removal efficiency. The results showed that the three-phase three-dimensional electrodes could effectively remove formic acid. Its COD removal efficie

Continuing our work toward a system mimicking the electron-transfer steps from manganese to P680+ in photosystem II (PS II), we report a series of ruthenium(II)-manganese(II) complexes that display intramolecular electron transfer from manganese(II) to photooxidized ruthenium(III). The electron-transfer rate constant (kET) values span a large range, 1 × 105-2 × 107 s-1, and we have investigated di

In this paper. we construct a homogeneous spatio-temporal model to describe the variability of significant wave height over small regions of the sea and over short periods of time. Then. the model is extended to a non-homogeneous one that is valid over larger areas of the sea and for time periods of up to 10 h. To validate the proposed model. we reconstruct the significant wave height surface unde