The lifetime risk of developing atrial fibrillation (AF) is estimated to be between 1in 3 to 1 in 4 individuals, making it the most common arrhythmia in the world.For persistent AF, rate control drugs with the purpose to affect the conduction properties of the atrioventricular (AV) node are the most common treatment. The drug of choice varies between β-blockers and calcium channel blockers, often

Background: Optimal oxygen targets in patients resuscitated after cardiac arrest are uncertain. The primary aim of this study was to describe the values of partial pressure of oxygen values (PaO2) and the episodes of hypoxemia and hyperoxemia occurring within the first 72 h of mechanical ventilation in out of hospital cardiac arrest (OHCA) patients. The secondary aim was to evaluate the associatio

Background: Preterm birth and fetal growth restriction (FGR) are associated with structural and functional kidney changes, increasing long-term risk for chronic kidney disease and hypertension. However, recent studies in preterm children are conflicting, indicating structural changes but normal kidney function. This study therefore assessed kidney structure and function in a cohort of adolescents

Detection of single, itinerant microwave photons is an important functionality for emerging quantum technology applications as well as of fundamental interest in quantum thermodynamics experiments on heat transport. In a recent experiment [W. Khan et al., Nat. Commun. 12, 5130 (2021)], it was demonstrated that a double quantum dot (DQD) coupled to a microwave resonator can act as an efficient and

In this article, we undertake a narrative analysis of social science teaching in Swedish upper secondary school as a case study. In doing so, we want to stress the need to pay attention to the contextual and situated limits and openings of the conceivable repertoire of legitimate stories of social science in the Swedish context and its related research. The students’ attempts at sense making and a

With the continuous increase of rapid urbanization and population growth, sustainable urban land-use planning is becoming a more complex and challenging task for urban planners and decision-makers. Multi-objective land-use allocation can be regarded as a complex spatial optimization problem that aims to achieve the possible trade-offs among multiple and conflicting objectives. This paper proposes

Personalized learning tailors material and strategy to student requirements, interests, and goals in e-learning. These developments help educational institutions and other organizations to keep up with the fast pace of information technology, communications, and computing power. Studies show that self-adaptive learning and relevant learning information improve study efficiency. Compared to traditi

Glial cell line-derived neurotrophic factor (GDNF) has been shown to counteract seizures when overexpressed or delivered into the brain in various animal models of epileptogenesis or chronic epilepsy. The mechanisms underlying this effect have not been investigated. We here demonstrate for the first time that GDNF enhances GABAergic inhibitory drive onto mouse pyramidal neurons by modulating posts

Denna antologi är ett arbete som varenda människa med något intresse för mänsklighet och samhällsfrågor måste läsa och reflektera över. De samlade berättelserna, undersökningarna och rapporterna som presenteras i antologin utgör en tvärvetenskaplig samtidsanalys över det svenska myndighetssystemet och dess inverkan på människoöden, kanske för generationer framåt.De samlade berättelserna, undersökningarna och rapporterna som presenteras i antologin utgör en tvärvetenskaplig samtidsanalys över det svenska myndighetssystemet och dess inverkan på människoöden, kanske för generationer framåt.

Recension av Gellert Hardi-Kovacs, Hemligast av alla – C-byrån. Berättelsen om Sveriges hemliga underrättelse under andra världskriget.

States in the Global South are facing a double challenge of achieving socio-economic development while adapting to climate change impacts. This study maps to what extent Small Island Developing States (SIDS) manage to meet the Sustainable Development Goals (SDGs). The SIDS are at the front line of climate change and while they share numerous challenges, the SIDS are also a heterogeneous group cont

Localization and mapping is the foundational technology for augmented reality (AR) that enables sharing and persistence of digital content in the real world. While significant progress has been made, researchers are still mostly driven by unrealistic benchmarks not representative of real-world AR scenarios. In particular, benchmarks are often based on small-scale datasets with low scene diversity,