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Change blindness in higher-order thought : Misrepresentation or good enough?

To evaluate the explanation of change blindness in terms of misrepresentation and determine its role for David Rosenthal’s higher-order thought theory of consciousness, we present an alternative account of change blindness that affords an independent outlook and provides a viable alternative. First we describe Rosenthal’s actualism and the notion of misrepresentation, then introduce change blindne

The normal squamocolumnar junction is circumferentially even and minimal irregularities are manifestations of gastroesophageal acid reflux

Background: The macroscopic appearance of the normal squamocolumnar junction (SCJ) is often described as serrated with short projections of columnar mucosa that extend into the esophagus. As studies of the normal SCJ are sparse, the aim of this study was to test the hypothesis that the normal SCJ is even and that irregularities are manifestations of acid reflux. Method: Fifty asymptomatic subjects

CP40 from Corynebacterium pseudotuberculosis is an endo-β-N-acetylglucosaminidase

Background: C. pseudotuberculosis is an important animal pathogen that causes substantial economical loss in sheep and goat farming. Zoonotic infections in humans are rare, but when they occur they are often severe and difficult to treat. One of the most studied proteins from this bacterium, the secreted protein CP40 is being developed as a promising vaccine candidate and has been characterized as

Association between antithrombotic treatment and hemorrhagic stroke in patients with atrial fibrillation—a cohort study in primary care

Objective: The objective of this study was to study the association between antithrombotic treatment and risk of hemorrhagic stroke (HS) in patients with atrial fibrillation (AF) treated in primary health care. Methods: Study population included all adults (n = 12,215) 45 years and older diagnosed with AF at 75 primary care centers in Sweden 2001–2007. Outcome was defined as a first hospital episo

Photochemistry of Carboxylate on TiO2(110) Studied with Synchrotron Radiation Photoelectron Spectroscopy

We present a dedicated synchrotron radiation photoelectron spectroscopy (SR-PES) study of a photochemical reaction on the surface of rutile TiO2(110). The photoreaction kinetics of carboxylate species (trimethyl acetate, TMA) upon irradiation by UV and soft X-rays were monitored, and we show that it is possible to control the reaction rates from UV light and soft X-rays independently. We directly

The Aggregation Paths and Products of Aβ42 Dimers Are Distinct from Those of the Aβ42 Monomer

Extracts of Alzheimer's disease (AD) brain that contain what appear to be sodium dodecyl sulfate-stable amyloid β-protein (Aβ) dimers potently block LTP and impair memory consolidation. Brain-derived dimers can be physically separated the Aβ monomer, consist primarily of Aβ42, and resist denaturation by chaotropic agents. In nature, covalently cross-linked Aβ dimers could be generated in two ways:

An Evaluation of Information Meetings as a Tool for Addressing Fear of Large Carnivores

Managing authorities in Scandinavia arrange public information meetings when members of the public express fear because wolves or brown bears approach human settlements. This study aimed to increase the understanding of the potential effect of information meetings on self-reported fear of wolves and brown bears. In total, 198 participants completed questionnaires before and after the information m

Herbivore teeth predict climatic limits in Kenyan ecosystems

A major focus in evolutionary biology is to understand how the evolution of organisms relates to changes in their physical environment. In the terrestrial realm, the interrelationships among climate, vegetation, and herbivores lie at the heart of this question. Here we introduce and test a scoring scheme for functional traits present on theworn surfaces of large mammalian herbivore teeth to captur

Labouring to Learn : Union Renewal in Swedish Manufacturing

As a response to post-Fordist production conditions, Swedish manufacturing unions have sought to develop their respective agendas beyond the traditional focus on distribution issues. A new emphasis on competence at the workplace suggests an increasing need for unions to develop a capacity to learn as organisations. The thesis accordingly sets out to further our theoretical knowledge of change in t

Methodology and Applications of Visual Stance Analysis : An Interactive Demo

Analysis of stance in textual data can reveal the attitudes of speakers, ranging from general agreement/disagreement with other speakers to fine-grained indications of wishes and emotions. The implementation of an automatic stance classifier and corresponding visualization techniques facilitates the analysis of human communication and social media texts. Furthermore, scholars in Digital Humanities

Polymorphisms in ATP-binding cassette transporters associated with maternal methylmercury disposition and infant neurodevelopment in mother-infant pairs in the Seychelles Child Development Study

Background: ATP-binding cassette (ABC) transporters have been associated with methylmercury (MeHg) toxicity in experimental animal models. Aims: To evaluate the association of single nucleotide polymorphisms (SNPs) in maternal ABC transporter genes with 1) maternal hair MeHg concentrations during pregnancy and 2) child neurodevelopmental outcomes. Materials and methods: Nutrition Cohort 2 (NC2) is

Brev som liv och konst. Brevväxlingen mellan Lilli Jahn och hennes barn

The letters between the jewish Lilli Jahn and her four young children during 1943 and 1944 are analyzed as representation of reality, i e the terrible situation and fate of Lilli Jahn (murdered in Auschwitz) and the children, and as art, the conscious forming of the letters of Jahn, adhering to the norms of the familiar letter.

Denitrification and DNRA at the Baltic Sea oxic–anoxic interface : Substrate spectrum and kinetics

The dependence of denitrification and dissimilatory nitrate reduction to ammonium (DNRA) on different electron donors was tested in the nitrate-containing layer immediately below the oxic–anoxic interface (OAI) at three stations in the central anoxic basins of the Baltic Sea. Additionally, pathways and rates of fixed nitrogen transformation were investigated with 15N incubation techniques without

Emotional kinship care and neutral non-kinship care - the struggle between discourses

In this paper, social workers' ideas of kinship care and non-kinship care as foster placement alternatives for vulnerable children are analysed and discussed. The study is based on group interviews with Swedish social workers, using a discourse analytic approach. The interviews took two vignettes of children who needed an immediate and long-term placement because one of the parents had killed the

Throat related symptoms and voice : development of an instrument for self assessment of throat-problems

BACKGROUND: Symptoms from throat (sensation of globus; frequent throat clearing; irritated throat) are common in patients referred to voice clinics and to ENT specialists. The relation to symptoms of voice discomfort is unclear and in some cases patients do not have voice problems at all. Instruments for patients' self-reporting of symptoms, and assessment of handicap, such as the Voice Handicap I

A FISH-based method for assessment of HER-2 amplification status in breast cancer circulating tumor cells following CellSearch isolation

Amplification of the HER-2/neu (HER-2) proto-oncogene occurs in 10%–15% of primary breast cancer, leading to an activated HER-2 receptor, augmenting growth of cancer cells. Tumor classification is determined in primary tumor tissue and metastatic biopsies. However, malignant cells tend to alter their phenotype during disease progression. Circulating tumor cell (CTC) analysis may serve as an altern

High expression of stromal PDGFRβ is associated with reduced benefit of tamoxifen in breast cancer

Cancer-associated fibroblasts (CAFs) regulate tumour growth, metastasis and response to treatment. Recent studies indicate the existence of functionally distinct CAF subsets. Suggested mechanisms whereby CAFs can impact on treatment response include paracrine signaling affecting cancer cell drug sensitivity and effects on tumour drug uptake. PDGFRβ is an important regulator of fibroblasts. Experim