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To achieve high selectivity in directed C–H activation, an NHC ligand was introduced to a palladium catalyst. A range of Pd-PEPPSI complexes were applied in the direct acetoxylation of 2-phenylpyridine. The best catalyst was found to be the one based on a diisopropylphenyl-substituted NHC ligand, and this was successfully used for the functionalization of sp2as well as more challenging sp3bonds fo
Background: Central nervous system (CNS) involvement is associated with relapse in childhood acute lymphoblastic leukemia (ALL) and is a diagnostic challenge. Procedure: In a Nordic/Baltic prospective study, we assessed centralized flow cytometry (FCM) of locally fixed cerebrospinal fluid (CSF) samples versus local conventional cytospin-based cytology (CC) for detecting leukemic cells and evaluati
A new health surveillance protocol for work-related upper-extremity musculoskeletal disorders has been validated by comparing the results with a reference protocol. The studied protocol, Health Surveillance in Adverse Ergonomics Conditions (HECO), is a new version of the reference protocol modified for application in the Occupational Health Service (OHS). The HECO protocol contains both a screenin
This paper presents a wideband quadrature radio receiver employing ΔΣ-based A/D-converting channel-select filters (ADCSFs). The output of the quadrature passive mixer is directly connected to the input of the ADCSFs, where a first-order ΔΣ modulator is incorporated into a fourth-order Butterworth channel-select filter (CSF) to provide sufficient dynamic range for a cellular system. A design method
We present a simple method to quantify the magnitude of luminescent coupling (LC) between stacked subcells in multijunction photovoltaic devices. The effect of luminescence produced at high-band-gap subcells on underlying low-gap units within the same device can be directly accessed as a measurable open-circuit voltage difference by comparing two photovoltage spectra. Additionally, our study unamb
Primary and chemically enhanced primary wastewater treatment with microsieving (disc or drum filtration) was studied at the large pilot scale at seven municipal wastewater treatment plants in Europe. Without chemical dosing, the reduction of suspended solids (SS) was (on average) 50% (20-65%). By introducing chemically enhanced primary treatment and dosing with cationic polymer only, SS removal co
Climate governance beyond the United Nations Framework Convention on Climate Change (UNFCCC)—including countries, companies, civil society, and international organizations, forming cooperative initiatives—is increasingly framed as complementing, supporting, and even substituting the multilateral negotiations. Cooperative initiatives activating nonstate actors could help bridging the ‘ambition gap’
Glycosaminoglycans (GAGs) are charged polysaccharides ubiquitously present at the cell surface and in the extracellular matrix. GAGs are crucial for cellular homeostasis, and their metabolism is altered during pathological processes. However, little consideration has been given to the regulation of the GAG milieu through pharmacological interventions. In this review, we provide a classification of
Moving beyond the distinction between biological and social facts has proved challenging due to several basic methodological and ontological differences among scientific disciplines. The aim of this paper is to show how attention schema theory (hereafter AST), developed by Michael Graziano, provides a useful addition to existing integrative approaches that can be used to overcome impediments to inMoving beyond the distinction between biological and social facts has proved challenging due to several basic methodological and ontological differences among scientific disciplines. The aim of this paper is to show how attention schema theory (hereafter AST), developed by Michael Graziano, provides a useful addition to existing integrative approaches that can be used to overcome impediments to in
In the wake of the economic and social crisis, Spanish fiction has looked for ways of reflecting (on) the political. One of the manners has been to attempt to understand how the crisis has affected subjectivity and, more concretely, how the subject navigates the society of the crisis. In this article, I study three recent novels—Alberto Olmos’ Ejército enemigo (2011), Bruno Galindo’s El público (2
In this essay, we oppose current conceptualizations of anger as, at least, a temporary individual psychological disorder and as the cause of a social disorder. We develop the view that anger can be a profoundly moral emotion aimed at maintaining moral order and restoring social order when this has been ruptured. Moral anger is distinguished from other types of anger, like the ones arising from rou
BACKGROUND: In 2008, the Swedish government introduced a National Rehabilitation Program, in which the government financially reimburses the county councils for evidence-based multimodal rehabilitation (MMR) interventions. The target group is patients of working age with musculoskeletal disorders (MSD), expected to return to work or remain at work after rehabilitation. Much attention in the evalua
A partir del fin de la Segunda Guerra Mundial se extiende, partiendo de los EEUU, una comprensión y uso de la ciencia subordinadas al proceso de producción. Esto determina el avance, sobre el campo científico, de un proceso de administración de la investigación y de la formación por parte del Estado y, a través de él, del aparato productivo. Esa subordinación de la actividad científica a la utilid
There is an increasing demand for real world evidence. The shift towards relative effectiveness assessment increasingly based on real world data is a natural consequence of the shift towards new adaptive pathways for development and introduction of new medicines in cancer care. The increasing number of alternative treatment options will further increase the need for outcomes data to help optimize
