Sepsis is a severe and often lethal inflammatory response to an infection. During sepsis the cells and organs no longer function as they should because of the intense immune response. Some of the cell dysfunction may be because of an important “sugar layer” known as the glycocalyx. In this study, we determined whether an inflammatory protein, heparin binding protein (HBP), might contribute to the

Approximately a quarter of a million women are diagnosed with ovarian cancer annually worldwide. Identifying the genes involved may ultimately lead to the development of corrective and preventive measures to fight this type of cancer. Next Generation Sequencing is a technology that can reveal the genes central to cancer initiation and development, however the analysis of the data is problematic du

This thesis investigates the interpretation of metaphorical expressions in Dante’s famous Inferno and how this may be motivated through the use of codes and inference. Based on Coseriu’s Integral Linguistics (Coseriu, 1985), metaphorical expressions can be divided depending on the kind of knowledge that is required to interpret them. The first level is the universal level where metaphors can be in

Sex chromosome evolution is a fascinating research topic because sex chromosomes provide a snapshot of evolution in many different lineages. Sex chromosomes often cease to recombine and therefore degenerate, and have also often been reshuffled during their evolution from autosomes. It has been discovered that within Sylvioidea passerine species half of chromosome 4a has translocated and fused with

Studien utgår från förekomsten av våld i samhället och våld som ett pedagogiskt problem. Syftet är att undersöka ung-domars och lärares attityder till fenomenet våld för att kunna anpassa preventiva åtgärder därefter. I studien an-vänds en kvalitativ ansats för att kartlägga hur elever och lärare på en skola uppfattar och beskriver våld, dess orsaker och möjligheterna att förebygga det. Datainsaml

The national day of Australia is Australia Day; a contentious public holiday that sparks a national debate on identity and multiculturalism every year. There are many different narratives that make up the Australian story, which encapsulates Australia’s diverse and multicultural history. Media plays a pivotal role in the representation of the national narrative; however, evidence of systemic power

In 2012 prostate cancer was the second most common cancer diagnose for men. The diagnosis is confirmed by pathologists doing ocular inspection of prostate biopsies and the specimens are classified according to the Gleason grading system. The main goal of this thesis is to automate the classification using Convolutional Neural Networks (CNN). With the introduction of Convolutional Neural Networks the

SAMMANFATTNING Apply Emtunga är ett företag som saknar struktur gällande sin orderprocess. Examensarbetets syfte är därför att kartlägga företagets orderprocess samt klarlägga vilka problem som uppstår i samband med denna. Examensarbetet ämnar därmed svara på följande tre frågor: - hur orderprocessen ser ut, vilka problem som kan identifieras i samband med orderprocessen samt vilka förslag på åtg

Sammanfattning Syftet med denna uppsats är att undersöka om, och i så fall vilken, betydelse mångfald har när en plats marknadsför sig mot dess invånare. Då vårt studieobjekt är Helsingborgs stad har vi applicerat våra teoretiska resonemang på huruvida en organisation använder mångfald i marknadsföring för att främja goda relationer mellan kommunen och invånarna. För att undersöka detta har vi gj

De nickel-kadmiumbatterier som tillverkas vid Saft AB i Oskarshamn är uppladdningsbara och används vanligen som backup för strömförsörjning på sjukhus, flygplatser och till och med för hela städer. Ett problem för nickel-kadmiumbatterier är upplösning av kadmiumhydroxid, det aktiva materialet i kadmiumelektroden. Utöver förlust av aktivt material kan det upplösta materialet bilda ett tunt lager påIn this project, the properties of Cd(OH)2 in alkaline solution were studied. The processes of oxidation and reduction for Cd(OH)2 in alkaline solution are very complex and even though many studies have been done on the subject, it is not completely understood yet. It is from a Ni-Cd battery point of view, important to understand these processes to prevent loss of active material. The Cd-electrode

Hybridization between species can be avoided by behavioural or physiological mechanisms that act as prezygotic and postzygotic reproductive barriers. In sympatric areas, where species come into contact, the maintenance of species distinctness will depend on the strength of such mechanisms. In cases with recent secondary contacts of closely related species, barriers are often incomplete and the out

Parkinson’s disease (PD) is the second most common neurodegenerative disorder and is characterized by a progressive loss of dopaminergic neurons (DNs) in substantia nigra pars compact and accumulation of aggregated forms of the protein α-synuclein known as Lewy Bodies (LBs). LBs are present in surviving DNs and other regions of the central nervous system (CNS) in PD patients. PD patients also disp

The whole word has been getting somewhat familiar with the crisis that the newspaper industry has been experiencing. The past decade has seen print mainly absorbing finances with little to no profits, and the ever-growing digital not offering enough advertising revenue. Hence, the challenges managers face becomes clear: how can we innovate effectively when the current system is a loophole? Additio

Improvement of cancer vaccines with the invariant chain molecule Cancer is a disease well known to most people and has been treated for many years through irradiation and different drugs. However, many developing cancers are never discovered because they are killed by the immune system before they are established. Similar to elimination of intruding bacteria, the immune system should under normal

Biological drugs such as tumor necrosis factor (TNFα) blockers are very successful and effective in therapy of chronic inflammatory disease. These blockers bind TNFα and inhibit its pro-inflammatory function. But unfortunately, biological drugs are immunogenic and prolonged treatment triggers the formation of anti-drug antibodies and neutralizing antibodies (NAbs). This reaction is associated with

What decides how plant litter is decomposed, and by whom? Trees take up carbon in form of atmospheric CO2 from the air and use as building material as they grow. This carbon, locked in plant material, enters the soil carbon cycle via aboveground litter for example in the form of fallen foliage, dead trees, lost bark or via the plants root system as root litter or root exudates. Fungi and bacteria

Hur känner växter kyla? Växter har, precis som djur, utvecklat en mängd olika responser på signaler från miljön de lever i. En av dessa är vernalisering. Vernalisering innebär att en växt blommar tidigare om den utsatts för en kalla temperaturer under en längre period än vad den annars skulle ha gjort. I detta projekt har vi kollat närmare på gener involverade i denna mekanism. För att vernalise

The Pacific marten (Martes caurina) is thought to be a forest specialist closely linked to older forests with high canopy cover and dense shrubs. It is therefore highly surprising that a small population have been found in the coastal sand dunes in Oregon, United States. The martens seem to be choosing this habitat even though large areas of older forests are available just next to the dunes. With

Does urbanisation make great tits clever? The expanding urban areas are changing the environment that the wildlife lives in. Most bird species avoid cities while some animals seem to prosper there. On the other hand, there are some species that live both in urban and rural areas without a preference for one. Such species are really interesting to study, because they can directly show the impact t

Tuberculosis (TB) is an infectious disease caused by a bacterium called Mycobacterium tuberculosis (Mtb). Infection occurs through inhalation of bacteria-containing droplets. After entry into the respiratory tract the bacteria mainly reside within macrophages in the lung by using different strategies to escape killing by the immune system. The attenuated Mycobacterium bovis strain Bacille Calmette