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Next-generation sequencing methods have revolutionized the speed of generating variation information. Sequence data have a plethora of applications and will increasingly be used for disease diagnosis. Interpretation of the identified variants is usually not possible with experimental methods. This has caused a bottleneck that many computational methods aim at addressing. Fast and efficient methods
Purpose: To study the phenotype in two families with genetically identified autosomal dominant retinitis pigmentosa (adRP) focusing on macular structure and function. Methods: Clinical data were collected at the Department of Ophthalmology, Lund University, Sweden, for affected and unaffected family members from two pedigrees with adRP. Examinations included optical coherence tomography (OCT), ful
To achieve cleaner combustion and higher efficiency in compression ignition (CI) engines, many new combustion strategies have been developed. Among these new concepts, partially premixed combustion (PPC) attracts a lot of attention, because of its possibility to achieve simultaneously low soot and NOx. Compared to homogeneous charge compression ignition (HCCI) combustion, charge stratification in
Women-focused development initiatives have become a controversial issue connected with women's health and welfare. Previous studies indicated that development initiatives might increase women's workload, family conflict, and marital violence. This study explored the gendered characteristics of a development initiative Rural Mother Center in Bangladesh. Data incorporated policy document and intervi
Background: In Europe, residential care homes (RCHs) are replacing hospitals as the place where death occurs, and they play an important role in end-of-life (EOL) care. Objective: The aim was to describe the quality of care during the last 3 months and last 3 days of life of those who died in RCHs as reported by family members. We also investigated whether there were differences in the EOL care of
Pneumococci isolated from the ear exudate in 245 children under 10 years of age afflicted with acute otitis media were typed. Types 3, 6, 14, 18, 19 and 23 were found in 80% of the cases. In the remaining cases, 15 other types were found. Five strains were not typable with the antisera used. Types 14 and 23 were found twice as often in the age group 0-3 years as in the higher age groups, whereas t
Optothermal spectrometry measures the thermal energy produced as a result of absorption by molecules at a given modulation frequency and wavelength. Depending on the modulation frequency used, analysis can be performed in very thin layers (50—150 micrometers). A major advantage of optothermal spectrometry is that it is not very sensitive to light scattering. Haemoglobin in whole blood was measured
This chapter explores gay and lesbian police officers’ stories of marginalization and the limits of inclusive diversity policies in the Swedish police. The analysis aims to go beyond the level of policy and formal training and consider mechanisms of exclusion and marginalization on the level of personal stories based on lived experience. Drawing on an interview study of gay and lesbian police offi
