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Prospects and Challenges for the Computational Social Sciences.

Computational social sciences (CSS) refer to computer-enabled investigations of human behaviour and social interaction. They include three main components - (i) computational modelling and social simulation, (ii) the analysis of digital traces of online interactions, (iii) virtual labs and online experiments - and allow researchers to perform studies that were even hard to imagine a few decades ag

Predictors of narrative text quality in students with hearing loss

Aim: Students with hearing loss (HL) often fall behind hearing peers in complex language tasks such as narrative writing. This study explored the effects of school grade, gender, cognitive and linguistic predisposition and audiological factors on narrative text quality in this target group.Method: Eleven students with HL in Grades 5–6 and 7–8 (age 12–15) who took part in a writing intervention wro

Is Aortic Z-score an Appropriate Index of Beneficial Drug Effect in Clinical Trials in Aortic Aneurysm Disease?

Aortic Z-score (Z-score) is utilized in clinical trials to monitor the effect of medications on aortic dilation rate in Marfan (MFS) patients. Z-scores are reported in relation to body surface area and therefore are a function of height and weight. However, an information void exists regarding natural, non-pharmacological changes in Z-scores as children age. We had concerns that Z-score decrease a

Collecting Muldoon

Review of Paul Muldoon, Poems 1968-1998, New York: Farrar, Straus and Giroux, 2001

Measurements of top-quark pair single- and double-differential cross-sections in the all-hadronic channel in pp collisions at √s = 13 TeV using the ATLAS detector

Differential cross-sections are measured for top-quark pair production in the all-hadronic decay mode, using proton-proton collision events collected by the ATLAS experiment in which all six decay jets are separately resolved. Absolute and normalised single- and double-differential cross-sections are measured at particle and parton level as a function of various kinematic variables. Emphasis is pl

Pregnancies, ventricular arrhythmias, and substrate progression in women with arrhythmogenic right ventricular cardiomyopathy in the Nordic ARVC Registry

AIMS: Women with arrhythmogenic right ventricular cardiomyopathy (ARVC) are at relatively lower risk of ventricular arrhythmias (VAs) than men, but the physical burden associated with pregnancy on VA risk remains insufficiently studied. We aimed to assess the risk of VA in relation to pregnancies in women with ARVC. METHODS AND RESULTS: We included 199 females with definite ARVC (n = 121) and muta

Validity of polymyalgia rheumatica diagnoses and classification criteria in primary health care

Objectives: PMR is an inflammatory disease with prominent morning stiffness and muscular tenderness, usually diagnosed in primary health care (PHC). The objectives were to examine the validity of PMR diagnoses in PHC and to validate the use of classification criteria for PMR.Methods: Medical records for patients with a registered PMR diagnosis at two PHC facilities were reviewed. Patients were cla

Frequency and Correlation of Common Genes Copy Number Alterations in Childhood Acute Lymphoblastic Leukemia with Prognosis

OBJECTIVE: It was shown by genomic profiling that despite no detectable chromosomal abnormalities a proportion of children with pre-B acute lymphoblastic leukemia harbors copy number alterations (CNA) of genes playing role in B-cell development and function. The aim of the study was to determine the frequency of CNA in pediatric acute lymphoblastic leukemia and correlate these findings with clinic

Guilt-tripping : On the relation between ethical decisions, climate change and the built environment

The curiosity of how the built environment, implicitly and explicitly, affects how citizens and users make choices in their everyday life related to climate change is on the rise. If there is a nicely designed bike lane, the choice to bike to work is much more easily taken than if the only option is a densely trafficked road. But which responsibility does the built environment have for citizens to

Possibly specific immune complexes in sera of patients with untreated acute myelogenous leukemia

Eleven patients with acute myelogenous leukemia (AML) in the acute stage of the disease were studied. Sera of seven patients were assayed for complement‐dependent cytotoxicity to autochthonous AML cells and sera of four patients were tested with allogeneic target cells before and after ultrafiltration at low pH. No specific cytotoxic activity could be detected in any untreated sera. Ultrafiltratio

Studies on adenovirus type 9‐induced mammary fibroadenomas in rats and their malignant transformation

After inoculating newborn W/Fu rats with adenovirus type 9,27 of 27 females developed mammary fibroadenomas with a latency period of 14–25 weeks. No tumors were observed after inoculation with adenovirus type 5 or in males with the type 9 inoculation. After persistence of the tumors for 3–14 months, malignant transformation of the stroma resulted in different types of sarcoma in three rats: fibros