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Trends in omnichannel logistics: a survey study with Swedish retailers
PurposeThe purpose of this study is to understand current trends and challenges in omnichannel logistics.Based on the study findings, a number of propositions are formulated.Design/methodology/approachAn exploratorysurvey study is conducted with 28Swedish retail companies that are involved with or plan to engage in omnichannel logistics. The study investigates the retailers’ previous andcurrent si
Warehousing trends and challenges in omni-channel logistics
Retail companies increasingly shift to an omni-channelstrategy, allowingconsumers tointeract through a single seamless interface of integrated channels. Thisomni-channeltrend put pressure onlogistics and,particularly, warehousing activities, which need tocombinefulfilment ofretail store-replenishment and web-based consumer orders in an effective and efficient way. This explorative study discussest
MRI-targeted or standard biopsy for prostate-cancer diagnosis
BACKGROUND: Multiparametric magnetic resonance imaging (MRI), with or without targeted biopsy, is an alternative to standard transrectal ultrasonography-guided biopsy for prostate-cancer detection in men with a raised prostate-specific antigen level who have not undergone biopsy. However, comparative evidence is limited. METHODS: In a multicenter, randomized, noninferiority trial, we assigned men
Brain cortical fatty acids and phospholipids during and following complete and severe incomplete ischemia
Loss of MafA and MafB expression promotes islet inflammation.
Maf transcription factors are critical regulators of beta-cell function. We have previously shown that reduced MafA expression in human and mouse islets is associated with a pro-inflammatory gene signature. Here, we investigate if the loss of Maf transcription factors induced autoimmune processes in the pancreas. Transcriptomics analysis showed expression of pro-inflammatory as well as immune cell
Gråt inte mer Cecilia, Inte du heller Ursula
Kris: Jag kommer aldrig förlåta nån av er
Will the R in R&D at large technology corporations disappear? : The demise of the ‘R’ in corporate R&D: is academia stepping up to the challenge?
The author has as a practitioner in industry for 25 years seen a shift in the attitude to corporateresearch. Previously, most established technology firms had substantial departments doing research.Over the years this has changed, and corporate research not seen as short term profitable hasdecreased.A number of papers indicate that the amount of in-house science in technology corporations isindeed
The Interorganizational Learning Dilemma : Collective Knowledge Development in Strategic Alliances
Alliances are volatile key components of many corporations' competitive strategies. They offer fast and flexible means of achieving market access, scale economies, and competence development. However, strategic alliances can encounter difficulties that often lead to disappointing performance. The authors suggest that the way partners manage the collective learning process plays a central role in t
Corporate strategy in a small open economy : Reducing product diversification while increasing international diversification
This study has investigated the changes in corporate strategy and performance in 20 large Swedish MNC's between 1985, 1994 and 1998. It has found a strong pattern of product focusing, increased internationalisation, and a strong increase in accounting-based performance. This development seems to be contrary to former empirical evidence, that international diversification pays off better for more p
37,2° — From her to eternity
Knee abduction during drop jump does not predict future anterior cruciate ligament injury in females : A systematic review and meta-analysis of prospective studies
Users influence in social-service innovations : Two swedish case studies
This article uses case studies to address the sources of social innovation, a major contributor to economic growth and welfare services. Following the findings of user-innovation research in the commercial sector, the authors found that social-problem users innovate new social services for solving specific social problems. They also found that superior problem and solution knowledge is one reason
Researching mergers and acquisitions with the case study method : Idiographic understanding of longitudinal integration processes
External ventricular drainage catheters : effect of surface heparinization on bacterial colonization and infection
Surface heparinization of central venous catheters has earlier been shown to reduce the frequency of bacterial colonization and septicaemia. The present study was undertaken to investigate the benefit of surface heparinization of external ventricular drainage (EVD) catheters in relation to bacterial colonization, as measured by bacterial growth and examination by a 16S-rRNA PCR assay, of catheters
Alterations of Akt1 (PKBalpha) and p70(S6K) in transient focal ischemia
The serine-threonine kinase Akt1 promotes cell survival through inhibition of apoptosis. One of the potential downstream targets of Akt1 is p70 S6 kinase, p70(S6K), an enzyme implicated in the regulation of protein synthesis. In this study, we investigated the changes in total and phosphorylated levels of Akt1 and p70(S6K) during transient focal ischemia. Male Wistar rats were subjected to 2 h of
Regression of intracerebral rat glioma isografts by therapeutic subcutaneous immunization with interferon-gamma, interleukin-7, or B7-1-transfected tumor cells
Progress in the definition of the roles of various costimulators and cytokines in determining the type and height of immune responses has made it important to explore genetically altered tumor cells expressing such molecules for therapeutic immunizations. We have studied the effect of therapeutic subcutaneous (s.c.) immunizations on the growth of preexisting intracerebral brain tumor isografts in
Cure of established, intracerebral rat gliomas induced by therapeutic immunizations with tumor cells and purified APC or adjuvant IFN-gamma treatment
We have previously reported that immunizations with mutagen-induced immunogenic variants of a weakly immunogenic rat glioma could protect against isografts of the original tumor cells. In this study we show that prolonged survival and cures of rats with established gliomas in their brains can be achieved by therapeutic immunizations with tumor cell mutants, combined with in vitro and in vivo inter
Mechanisms of secondary brain injury
The mechanisms which lead to secondary brain damage following transient ischaemia are incompletely defined. As discussed in this hypothesis article, the events which lead to such damage could encompass (a) a perturbed membrane handling of calcium, leading to a slow, gradual increase in the free cytosolic calcium concentration (Ca2(i)), with subsequent calcium overload of mitochondria, (b) a sustai