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Finite element analysis of some problems in connection with intergranular stress corrosion cracking

Elasto plastic analysis was performed to determine the conditions at the root of a notch in a CERT specimen and the conditions at a crack growing in a CERT specimen. Furthermore. analysis of growth under small scale yielding was performed in order to facilitate analysis of compact tension specimen. By experiments it was shown how the stress strain conditions affect initiation of intergranular crac

Detection of circulating tumor cells and circulating tumor DNA before and after mammographic breast compression in a cohort of breast cancer patients scheduled for neoadjuvant treatment

PurposeIt is not known if mammographic breast compression of a primary tumor causes shedding of tumor cells into the circulatory system. Little is known about how the detection of circulating biomarkers such as circulating tumor cells (CTCs) or circulating tumor DNA (ctDNA) is affected by breast compression intervention.MethodsCTCs and ctDNA were analyzed in blood samples collected before and afte

Evolution of averaged local premixed flame thickness in a turbulent flow

In the combustion literature, contradictory results on the influence of turbulence on the local thickness of a premixed flame can be found and the present paper aims at contributing to reconcile this issue. First, different measures of local flame thickness in a turbulent flow, e.g. area-weighted and unweighted surface-averaged values of (i) |∇c|, i.e., the absolute value of 3D gradient of the com

Sjuttiofem år efter Nils Hylander : nytt ljus över engelska landskapsparker och deras flora i Sverige

During World War II, Nils Hylander worked on his monumental theses about the wood lawn neophytes [German: Grassameneinkömmlinge] of Swedish parks. Most probably, the original aim was to date and locate the sources of the imported seed that had obviously been widely used in the 1800’s for establishing lawns in parks of the English style, but due to restrictions to work and travel during the war, Hy

A review of assessment methods for the urban environment and its energy sustainability to guarantee climate adaptation of future cities

The current climate change is calling for a drastic reduction of energy demand as well as of greenhouse gases. Besides this, cities also need to adapt to face the challenges related to climate change. Cities, with their complex urban texture and fabric, can be represented as a diverse ecosystem that does not have a clear and defined boundary. Multiple software tools that have been developed, in re

Caregiving and infants' neurodevelopment in rural Costa Rica : Results from the Infants’ Environmental Health Study (ISA)

Early caregiving is one of the strongest influences on children's development, and among the most significant modifiable environmental factor. The aim of this study was to explore the association between quality of caregiver-infant interactions and neurodevelopment of infants living in banana-growing communities in rural Costa Rica characterized as having environmental toxic exposures. Home visits

Neutrophils from ANCA-associated vasculitis patients show an increased capacity to activate the complement system via the alternative pathway after ANCA stimulation

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV), including granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), are autoimmune conditions associated with small vessel inflammation. Earlier studies indicate that complement activation via the alternative pathway plays a major role in the pathogenesis. In this study we have investigated if ANCA-activati

Reasons for Discontinuing Active Surveillance : Assessment of 21 Centres in 12 Countries in the Movember GAP3 Consortium

Background: Careful assessment of the reasons for discontinuation of active surveillance (AS) is required for men with prostate cancer (PCa). Objective: Using Movember's Global Action Plan Prostate Cancer Active Surveillance initiative (GAP3) database, we report on reasons for AS discontinuation. Design, setting, and participants: We compared data from 10 296 men on AS from 21 centres across 12 co

Feasibility study on a novel heat exchanger network for cryogenic liquid regasification with cooling capacity recovery : Theoretical and experimental assessments

There is an increasing research interest in the recovery of cooling capacity stored in cryogenic liquids (CLs) for industrial applications, especially for LNG regasification systems. In this study, a novel heat exchanger network (HEN) has been designed for cryogenic liquid regasification process to recover the released cooling capacity and develop a frozen-free heat transfer system with compact st

Integration of a complete downstream process for the automated lab-scale production of a recombinant protein

In this work, an automated downstream process for the purification and formulation of a recombinant protein was integrated at lab scale in a single chromatography unit. The purification chain consists of three bind-and-elute chromatography columns, a flow-through membrane chromatography step, and a final ultrafiltration-diafiltration (UFDF) step to concentrate and formulate the sample. An integrat

Analysis of Pharmaceutical Industry Payments to UK Health Care Organizations in 2015

Importance: Drug company payments to health care organizations can create conflicts of interest. However, little is known about such financial relationships, especially outside the United States.Objective: To examine the concentration and patterns of drug company payments to health care organizations in the United Kingdom.Design, Setting, and Participants: This cross-sectional study examined nonre

Development of novel ultrasonic temperature measurement technology for combustion gas as a potential indicator of combustion instability diagnostics

In this study, a high-speed, fast responsive, non-intrusive ultrasonic thermometry system was proposed as a potential candidate for overcoming the disadvantages of thermocouples. The principle of this system is based on the thermal dependence of the speed of sound, and the temperature is measured by detecting the flight time of ultrasonic wave (USW) between the transmitter and the receiver. For a