Sökresultat

Filtyp

Din sökning på "*" gav 534685 sökträffar

Social capital and change in psychological health over time.

The positive association between social capital and general health outcomes has been extensively researched over the past decade; however, studies investigating social capital and psychological health show less consistent results. Despite this, policy-makers worldwide still employ elements of social capital to promote and improve psychological health. This United Kingdom study investigates the ass

Design of recombinant antibody microarrays for membrane protein profiling of cell lysates and tissue extracts.

Generating global protein expression profiles, including also membrane proteins, will be crucial for our understanding of biological processes in health and disease. In this study, we have expanded our antibody microarray technology platform and designed the first human recombinant antibody microarray for membrane proteins targeting crude cell lysates and tissue extracts. We have optimized all key

Laser-plasma electron acceleration in dielectric capillary tubes

Electron beams and betatron X-ray radiation generated by laser wakefield acceleration in long plasma targets are studied. The targets consist of hydrogen filled dielectric capillary tubes of diameter 150 to 200 microns and length 6 to 20 mm. Electron beams are observed for peak laser intensities as low as 5x10(17) W/cm(2). It is found that the capillary collects energy outside the main peak of the

Social capital and self-rated health – a study of temporal (causal) relationships

Despite the vast amount of research over the past fifteen years, there is still lively debate surrounding the role of social capital on individual health outcomes. This seems to stem from a lack of consistency regarding the definition, measurement and plausible theories linking this contextual phenomenon to health. We have further identified a knowledge gap within this field - a distinct lack of r

The De-Iconization and Rebuilding of Iconicity in Spatial Deixis

This paper investigates iconicity as a possible driving force behind the rebuilding of deictic systems and forms in individual languages. A comparison of a reconstructed Proto-Indo-European deictic system (based mainly on Beekes, Comparative Indo-European Linguistics: An Introduction, 1995) compared with the systems of attested Indo-European languages makes it clear that both systems and forms hav

In Situ Etching for Total Control Over Axial and Radial Nanowire Growth

We report a method using in situ etching to decouple the axial from the radial nanowire growth pathway, independent of other growth parameters. Thereby a wide range of growth parameters can be explored to improve the nanowire properties without concern of tapering or excess structural defects formed during radial growth. We demonstrate the method using etching by HCl during InP nanowire growth. Th

Unique subgraphs are not easier to find

Given a pattern graph H with l edges, and a host graph G guaranteed to contain at most one occurrence of a subgraph isomorphic to H, we show that the time complexity of the problem of finding such an occurrence (if any) in G as well as that of the decision version of the problem are within a multiplicative factor O(l) of the time complexity for the corresponding problem in the general case, when G

Enhanced Activity of Transforming Growth Factor beta 1 (TGF-beta 1) Bound to Cartilage Oligomeric Matrix Protein

Cartilage oligomeric matrix protein (COMP) is an important non-collagenous cartilage protein that is essential for the structural integrity of the cartilage extracellular matrix. The repeated modular structure of COMP allows it to "bridge" and assemble multiple cartilage extracellular matrix components such as collagens, matrilins, and proteoglycans. With its modular structure, COMP also has the p

Concerns About Falling in Parkinson's Disease: Associations with Disabilities and Personal and Environmental Factors.

Fear of falling can be conceptualized in different ways, e.g., as concerns about falling or low fall-related self-efficacy. It is common in people with Parkinson's disease (PD), and there is growing knowledge about its contributing factors. However, previous multivariate studies have mainly focused on fear of falling in relation to PD-related disabilities, and less is known about the associations

Response to Letter to the Editor 'Red cell distribution width in patients with atrial fibrillation'

RDW is a new and easily available risk marker for adverse cardiovascular outcomes and we agree that this may encourage a wider use in clinical practice. As pointed out by Balta et al [2], the underlying causal links are unclear. The causal links could hypothetically involve some of the factors mentioned by Balta et al [2], but also properties of the red cells per se. This article is protected by c

Which physics determines the location of the mean molecular weight minimum in red giants?

Stars ascending the red giant branch develop an inversion in mean molecular weight (mu) owing to the burning of He-3 in the region immediately above their hydrogen-burning shells. This inversion may drive thermohaline mixing and thereby be responsible for the extra mixing which is observationally indicated on the red giant branch. In this paper, we investigate the physical influences that determin

Quantized Conduction and High Mobility in Selectively Grown InxGa1-xAs Nanowires

We report measured quantized conductance and quasi-ballistic transport in selectively regrown In0.85Ga0.15As nanowires. Very low parasitic resistances obtained by regrowth techniques allow us to probe the near-intrinsic electrical properties, and we observe several quantized conductance steps at 10 K. We extract a mean free path of 180 +/- 40 nm and an effective electron mobility of 3300 +/- 300 c

Heme proteins in lactic Acid bacteria.

Lactic acid bacteria (LAB) are of profound importance in food production and infection medicine. LAB do not rely on heme (protoheme IX) for growth and are unable to synthesize this cofactor but are generally able to assemble a small repertoire of heme-containing proteins if heme is provided from an exogenous source. These features are in contrast to other bacteria, which synthesize their heme or d

Low-order feedforward controllers: Optimal performance and practical considerations

Feedforward control from measurable disturbances can significantly improve the performance in control loops. However, tuning rules for such controllers are scarce. In this paper design rules for how to choose optimal low-order feedforward controller parameter are presented. The parameters are chosen so that the integrated squared error, when the system is subject to a step disturbance, is minimize

Chiral-symmetric technicolor with standard model Higgs boson

Most of the traditional technicolor-based models are known to be in a strong tension with the electroweak precision tests. We show that this serious issue is naturally cured in strongly coupled sectors with chiral-symmetric vectorlike gauge interactions in the framework of the gauged linear sigma model. We discuss possible phenomenological implications of such a nonstandard chiral-symmetric techni

Levodopa--carbidopa intestinal gel for treatment of advanced Parkinson''s disease

Levodopa is the mainstay of Parkinson''s disease (PD) treatment, but is often eventually associated with disabling motor complications in patients with advanced PD. The inability of perorally administered levodopa to provide more physiologic continuous dopaminergic stimulation (CDS) is a leading hypothesis to explain these complications. To investigate the cumulative efficacy and safety, and re-ev