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Background: The cell surface glycoprotein E-cadherin (CDH1) is a key regulator of adhesive properties in epithelial cells. Germline mutations in CDH1 are well established as the defects underlying hereditary diffuse gastric cancer (HDGC) syndrome, and an increased risk of lobular breast cancer (LBC) has been described in HDGC kindreds. However, germline CDH1 mutations have not been described in pa
Investigation of lung clearance of 99mTc-labelled diethylene triamine penta-acetic acid (DTPA) in smoking sarcoid patients has been impeded by difficulties to differ between pathology of clearance kinetics caused by sarcoidosis and by smoking. This study explores the kinetics of lung clearance of 99mTc-DTPA in 15 current smokers with intrathoracic sarcoidosis. The results are compared with finding
We set up and analyze a random matrix model to study energy localization and its time behavior in two chaotically coupled systems. This investigation is prompted by a recent experimental and theoretical study of Weaver and Lobkis on coupled elastomechanical systems. Our random matrix model properly describes the main features of the findings by Weaver and Lobkis. Due to its general character, our
A large amount of scientific work has been carried out to enhance the methods used for design and control of technical systems. For many of these systems, the main objective is to utilize the limited resources in an optimal way. Different simulation techniques have, in many cases, been successfully applied to the analysis. When working with technical systems, it is important to have a common notat
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Pt (0.1 wt.%) on Al2O3, TiO2, and MgO supports were used for the low temperature combustion of methanol in both the absence and the presence of ammonia. Without NH3 in the gas the performance for the complete combustion decreases in the order Pt/MgO greater than or equal to Pt/TiO2 much greater than Pt/Al2O3 comparing a fixed amount of Pt surface area. In the presence of ammonia strong deactivatio
Wigner-von Neumann type perturbations of the periodic one-dimensional Schrodinger operator are considered. The asymptotics of the solution to the generalized eigenfunction equation is investigated. It is proven that a subordinated solution and therefore art embedded eigenvalue may occur at the points of the absolutely continuous spectrum satisfying a certain resonance (quantization) condition betw
An intervention consisting of individualized planned care for patients and regular clinical systematic supervision for nurses was carried out on a ward for dementia care (the experimental ward, EW). On a similar control ward (CW), no changes were made. Observations of nurse-patient cooperation during morning care were collected at both wards, before and during the intervention. The observations (N
Recension av Olle Hägers dokumentärfilmserie Hundra svenska år.
The selective breeding of Roman high- (RHA/Verh) and low-avoidance (RLA/Verh) rats for rapid versus poor acquisition of active avoidant behaviour has produced two behavioural phenotypes with different performances in a variety of animal models of anxiety, in which RLA/Verh rats are consistently more fearful than RHA/Verh rats. In addition, these two lines display different functional properties of
The digestibility of sludge is dependent on the content of organic extra-cellular polymeric substances. Currently the most appropriate and rapid assessment methods for the organic content of wastewater are the chemical oxygen demand and volatile solids values. These parameters also measure the non-biodegradable organics. We have developed a method to predict sewage sludge digestibility and the app
Detta är en antologi som består av exempel på empiriska studier där äldre människors varit involverade som subjekt. Resultatet visar att äldres teknikanvändning i vardagen problematiseras på tre nivåer. den första nivån fokuserar konstruktionen och utformningen av artefakten; den andra nivån användningen av tekniken i den vardagliga kontexten; den tredje nivån relationen mellan teknikutvecklingen
This work introduces a new approach to achieve a unimodal dome-shaped island population for the self-assembled Ge/Si (0 0 1) dots grown by ultra-high vacuum chemical vapour deposition at T = 620 degreesC. A step-wise growth mode is applied, consisting of two Ge deposition steps with a short growth interruption in between. In the first step, a "base structure" with pyramids and domes is grown while
The orchid genus Nigritella constitutes a polyploid complex which is widespread in mountain regions in Europe. Diploid members of the genus have sexual reproduction, whereas polyploid members are characterised by agamospermy. We used allozyme data to estimate levels of variation at different hierarchical levels and to describe the evolution of polyploids. - The variation patterns at allozyme loci
Objective. A low tidal volume can induce alveolar derecruitment in patients with acute lung injury. This study was undertaken to evaluate whether this resulted mainly from the decrease in tidal volume per se or from the reduction in end-inspiratory plateau pressure and whether there is any benefit in raising the level of positive end-expiratory pressure (PEEP) while plateau pressure is kept consta
The growing world electricity demand and environmental concerns pushes toward new technology for electricity production. Within the thermal processes for electricity production, two axis of research are being developed to meet the needs of the industry, namely using renewable fuels and new generation burners technology. The first direction is to develop new processes able to use renewable fuels. B
