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Value of Statistical Life and Cause of Accident: A Choice Experiment

The purpose of this study is to compare the value of statistical life (VSL) estimates for traffic, drowning, and fire accidents. Using a choice experiment in a mail survey of 5,000 Swedish respondents we estimated the willingness to pay for risk reductions in the three accidents. In the experiment respondents were asked a series of questions, whether they would choose risk reducing investments whe

Balancing Software Product Investments

The long-term sustainability of a software product depends on more than developing features. Priorities are placed on aspects that support the development of software, like software product quality (eg. ISO 9126), project constraints — time and cost, and even the development of intellectual capital (IC). A greater focus on any one aspect takes priority from another, but as each aspects delivers a

Androgens Inhibit the Stimulatory Action of 17β-Estradiol on Normal Human Breast Tissue in Explant Cultures.

Background: The data concerning the effects and safety of androgen in human breast tissue are conflicting. Objective: Our aim was to analyze the effects of androgens on normal human breast tissue (HBT). Approach: We cultured explants of HBT (obtained from reduction mammoplasty operations of postmenopausal women) with or without testosterone (T) and 5α-dihydrotestosterone (DHT) or in combination

EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis

The objective was to develop evidence -based recommendations and a research and educational agenda for the non-pharmacological management of hip and knee osteoarthritis (OA). The multidisciplinary task force comprised 21 experts: nurses, occupational therapists, physiotherapists, rheumatologists, orthopaedic surgeons, general practitioner, psychologist, dietician, clinical epidemiologist and patie

Building Performance - Methods for Improved Prediction and Verification of Energy Use and Indoor Climate

Popular Abstract in Swedish Byggnadsprestanda – Metoder för förbättrad prediktering och verifiering av energianvändning och inneklimat Hans Bagge, Byggnadsfysik LTH Introduktion För att kunna minska utsläpp av växthusgaser och rädda klimatet på jorden är det av yttersta vikt att vi kan bygga byggnader med låg energianvändning och bra inneklimat. Byggnader står i dagsläget för mellan 30 och 40 %Reducing CO2 emissions is one of the most important goals in Europe as well as the rest of the world. To reach that goal, the use of energy must be reduced. Thus, the building industry is facing a great challenge. Not only energy efficiency but also sustainability is desirable in the building stock. This thesis presents and suggests methods that can be used to improve prediction and verification o

European Association of Urology Guidelines on Vasectomy

Context: The European Association of Urology presents its guidelines for vasectomy. Vasectomy is highly effective, but problems can arise that are related to insufficient preoperative patient information, the surgical procedure, and postoperative follow-up. Objective: These guidelines aim to provide information and recommendations for physicians who perform vasectomies and to promote the provision

Comparison Between Two Models for Interactions Between Electric and Magnetic Fields and Proteins in Cell Membranes

Investigations on exposure to electromagnetic have generated conflicting results both in epidemiological and laboratory studies, leaving their possible health consequences largely inconclusive. One of the well-reported reasons for the discrepancies is that there is no generally accepted theory to describe the interactions between the very weak electromagnetic fields and the living cells. This work

Minimally modified LDL upregulates endothelin type B receptors in rat coronary artery via ERK1/2 MAPK and NF-kappa B pathways

Minimally modified low density lipoprotein (mmLDL) is a well-known risk factor for coronary artery disease. Upregulation of vascular endothelin type B (ETB) receptors on the vascular smooth muscle cells is predicted to be the molecular mechanism that leads to cardiovascular pathogenesis. The objective of the present study was to examine the hypothesis that mmLDL upregulates ETB receptors in rat co

Identification of a high-affinity network of secretagogin-binding proteins involved in vesicle secretion.

Secretagogin is a hexa EF-hand Ca(2+)-binding protein expressed in neuroendocrine, pancreatic endocrine and retinal cells. The protein has been noted for its expression in specific neuronal subtypes in the support of hierarchical organizing principles in the mammalian brain. Secretagogin has previously been found to interact with SNAP25 involved in Ca(2+)-induced exocytosis. Here, the cellular int

Effect of Treatment with Natalizumab on Ability to Work in People with Multiple Sclerosis Productivity Gain Based on Direct Measurement of Work Capacity before and after 1 Year of Treatment

Background: Sweden is a high endemic region for multiple sclerosis (MS), a neurologic disorder characterized by repeated inflammatory episodes affecting the CNS. The disease has its peak age of onset at approximately 30 years and affects women twice as often as men. The young age of onset makes MS one of the major causes of reduced capacity to work due to neurologic disease in Western society. Nat

Energy intake and sources of energy intake in the European Prospective Investigation into Cancer and Nutrition

Objectives: To describe energy intake and its macronutrient and food sources among 27 regions in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Methods: Between 1995 and 2000, 36 034 subjects aged 35-74 years were administered a standardized 24-h dietary recall. Intakes of macronutrients (g/day) and energy (kcal/day) were estimated usin

Themes and challenges in making supply chains environmentally sustainable

Purpose - The purpose of this article is to explore themes and challenges in making supply chains environmentally sustainable. Design/methodology/approach - The study began with a systematic review, and content analysis of articles in top-ranking related journals from logistics, transport, sustainability and environmental areas, and ended with research propositions contributing to the further ad

Gender specific age-related changes in bone density, muscle strength and functional performance in the elderly: a-10 year prospective population-based study

Background: Age-related losses in bone mineral density (BMD), muscle strength, balance, and gait have been linked to an increased risk of falls, fractures and disability, but few prospective studies have compared the timing, rate and pattern of changes in each of these measures in middle-aged and older men and women. This is important so that targeted strategies can be developed to optimise specif