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Objective: To review and highlight progress in otitis media (OM) research in the areas of immunology, inflammation, environmental influences and host-pathogen responses from 2019 to 2023. Opportunities for innovative future research were also identified. Data sources: PubMed database of the National Library of Medicine. Review methods: Key topics were assigned to each panel member for detailed rev
Background: Over the past years, it has become clear that the microbial ecosystem in the gut has a profound capacity to interact with the host through the production of a wide range of bioactive metabolites. The microbially produced metabolite imidazole propionate (ImP) is clinically and mechanistically linked with insulin resistance and type 2 diabetes, but it is unclear how ImP is associated wit
Measurements of joint-polarisation states of W and Z gauge bosons in W±Z production are presented. The data set used corresponds to an integrated luminosity of 139 fb−1 of proton–proton collisions at a centre-of-mass energy of 13 TeV recorded by the ATLAS detector at the CERN Large Hadron Collider. The W±Z candidate events are reconstructed using leptonic decay modes of the gauge bosons into elect
The flavour-tagging algorithms developed by the ATLAS Collaboration and used to analyse its dataset of s=13 TeV pp collisions from Run 2 of the Large Hadron Collider are presented. These new tagging algorithms are based on recurrent and deep neural networks, and their performance is evaluated in simulated collision events. These developments yield considerable improvements over previous jet-flavou
The literature on sustainability transitions increasingly recognizes that sectoral structures transcending national boundaries can both hinder and promote sustainability transitions. Yet there is only limited evidence on the roles of global actors in transforming entrenched socio-technical structures directly at the global scale. To explore the mechanisms of agency at the global scale, we develop
Background: Assessing malignancy risk is important to choose appropriate management of ovarian tumors. We compared six algorithms to estimate the probabilities that an ovarian tumor is benign, borderline malignant, stage I primary invasive, stage II-IV primary invasive, or secondary metastatic. Methods: This retrospective cohort study used 5909 patients recruited from 1999 to 2012 for model develo
Objective: To gain new insight into the molecular changes of the meniscus by comparing the proteome profiles of healthy controls with mild degeneration and end-stage osteoarthritis (OA). Method: We obtained tissue plugs from lateral and medial menisci of 37 individuals (central part of the posterior horn) classified as healthy (n = 12), mild signs of joint damage (n = 13) and end-stage OA (n
This paper presents a measurement of fiducial and differential cross-sections for W+W- production in proton–proton collisions at s=13 TeV with the ATLAS experiment at the Large Hadron Collider using a dataset corresponding to an integrated luminosity of 139 fb - 1 . Events with exactly one electron, one muon and no hadronic jets are studied. The fiducial region in which the measurements are perfor
Background: Simultaneous overrepresentations of contact allergies and photocontact allergies are common in individuals with photocontact allergy to ketoprofen. Aims: To investigate whether contact allergy to oxidised (ox.) geraniol, geraniol, geranial, neral and citral is overrepresented in individuals with photocontact allergy to ketoprofen. Methods: The contact allergy rates to ox. geraniol, ger
Recent years has seen an unprecedented growth in emerging technologies like Additive manufacturing (AM), augmenting the manufacturing capabilities through a multitude of opportunities while also introducing unique constraints, such as support structures, and post-processing requirements. Taking full advantage of the potential of AM demands product designs to be optimised for both opportunities and
A search for forward proton scattering in association with light-by-light scattering mediated by an axion-like particle is presented, using the ATLAS Forward Proton spectrometer to detect scattered protons and the central ATLAS detector to detect pairs of outgoing photons. Proton-proton collision data recorded in 2017 at a centre-of-mass energy of s = 13 TeV were analysed, corresponding to an inte
Marine biodiversity increased markedly during the Ordovician Period (~487–443 million years ago). Some intervals within the Ordovician were associated with unusually rapid and prominent rises in taxonomic richness, the reasons for which remain debated. Links between increased oxygenation and biodiversification have been proposed, although supporting marine oxygen proxy data are limited. Here we pr
A search for long-lived particles decaying into hadrons is presented. The analysis uses 139 fb−1 of pp collision data collected at s = 13 TeV by the ATLAS detector at the LHC using events that contain multiple energetic jets and a displaced vertex. The search employs dedicated reconstruction techniques that significantly increase the sensitivity to long-lived particles decaying in the ATLAS inner
Microcephaly is often caused by an impairment of the generation of neurons in the brain, a process referred to as neurogenesis. While most neurogenesis in mammals occurs during brain development, it thought to continue to take place through adulthood in selected regions of the mammalian brain, notably the hippocampus. However, the generality of neurogenesis in the adult brain has been controversia
Ongoing debates on spatial justice often highlight bottom-up struggles by movements making demands on the state. This kind of narrative certainly reflects the limitations imposed by decades of neoliberal reforms that have pushed back the formal influence of grassroots in many areas. With the hegemonic formation that sustained neoliberal rule in prolonged crisis, there are now more openings for rad
Background: The mercury isotopes around N=104 are a well-known example of nuclei exhibiting shape coexistence. Mixing of configurations can be studied by measuring the monopole strength ρ2(E0), however, currently the experimental information is scarce and lacks precision, especially for the Iπ→Iπ (I≠0) transitions. Purpose: The goals of this study were to increase the precision of the known branch
This article gives an overview of the contributions in the special issue of the International Journal of Strategic Communication on evolutionary psychology and strategic communication. Forward-looking, it argues that recent advances in artificial intelligence (AI) have made it imperative for our discipline to come to grips with a biologized view of the human mind as an information-processing syste
The Gaia-ESO Survey is a public spectroscopic survey that targeted ≲105 stars covering all major components of the Milky Way from the end of 2011 to 2018, delivering its final public release in May 2022. Unlike other spectroscopic surveys, Gaia-ESO is the only survey that observed stars across all spectral types with dedicated, specialised analyses: from O (Teff ∼ 30 000-52 000 K) all the way to K
Context. Giant planets are known to dominate the long-term stability of planetary systems due to their prevailing gravitational interactions, but they are also thought to play an important role in planet formation. Observational constraints improve our understanding of planetary formation processes such as the delivery of volatile-rich planetesimals from beyond the ice line into the inner planetar
