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Diagnosis and management of bone fragility in diabetes : an emerging challenge

Fragility fractures are increasingly recognized as a complication of both type 1 and type 2 diabetes, with fracture risk that increases with disease duration and poor glycemic control. Yet the identification and management of fracture risk in these patients remains challenging. This review explores the clinical characteristics of bone fragility in adults with diabetes and highlights recent studies

Principles for the design of a policy framework to address product life cycle impacts

Introduction: Product-oriented environmental law is an expanding, poly-thematic subsection of environmental law. First, an increasing number of policy instruments are being used at the international, European and national levels to regulate products, including mandatory performance standards, consumer subsidies, public procurement practices, product bans, taxes and charges and various kinds of man

An external beam PIXE/PESA setup for characterization of fine aerosols

An external beam setup has been developed for the determination of elemental concentrations in fine aerosols (aerodynamic particle diameter less than about 2 μm). Carbon, nitrogen and oxygen are determined with particle elastic scattering analysis (PESA) and, simultaneously, elements heavier than silicon with PIXE at a proton energy of 3.58 MeV. Earlier work on aerosols with PESA and most PIXE wor

Urban outdoor lighting : Pedestrian perception, evaluation and behaviour in the lit environment

Walking plays an essential role in sustainable transport systems, as nearly all journeys in the urban environment incorporate walking in one way or another. In parts of the world, for long periods of the year, seasonal variation in daylight hours means that pedestrians must rely on outdoor lighting to make cities accessible after dark. However, outdoor lighting is associated with considerable ener

Sewage sedimentation ponds - a lost bird paradise : a nostalgic return visit and case study

Sewage ponds with exposed sludge are known to be excellent feeding sites for waders during migration. They still exist in parts of the world but are disappearing in pace with introduction of modern methods which do not involve open exposure of the sludge. Here I report a five-year study from a Swedish plant with open sludge ponds in the 1950s when many similar ones were still active. I counted the

Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors

Myelin regeneration can occur spontaneously in demyelinating diseases such as multiple sclerosis (MS). However, the underlying mechanisms and causes of its frequent failure remain incompletely understood. Here we show, using an in-vivo remyelination model, that demyelinated axons are electrically active and generate de novo synapses with recruited oligodendrocyte progenitor cells (OPCs), which, ea

Analyzing atmospheric trace gases and aerosols using passenger aircraft

CARIBIC (Civil Aircraft for the Regular Investigation of the Atmosphere Based on an Instrument Container) resumed regular measurement flights with an extended scientific payload in December 2004. After an automated measurement container was successfully deployed on intercontinental flights using a Boeing 767 from 1997 to 2002, a far more powerful package now is deployed using a new Airbus A340‐600

Source identification during the Great Dun Fell Cloud Experiment 1993

A characterisation of the sources influencing the site for the final field campaign of the EUROTRAC subproject GCE (Ground-based Cloud Experiment) at Great Dun Fell, Cumbria, Great Britain in April-May 1993 is presented. The sources were characterised mainly by means of aerosol filter and cascade impactor data, single particle analysis, gas data, data on aromatic organic compounds, cloud water ion

Reports of the AAAI 2017 fall symposium series

The AAAI 2017 Fall Symposium Series was held Thursday through Saturday, November 9–11, at the Westin Arlington Gateway in Arlington, Virginia, adjacent to Washington, DC. The titles of the six symposia were Artificial Intelligence for Human-Robot Interaction; Cognitive Assistance in Government and Public Sector Applications; Deep Models and Artificial Intelligence for Military Applications: Potent

Resources for work-related well-being : A qualitative study about healthcare employees' experiences of relationships at work

Aims and objectives: To explore municipal healthcare employees' experiences of relationships with care recipients and colleagues. The specific research questions were when do the relationships enhance well-being, and what prerequisites are needed for such relationships to occur? Background: Employees in health and social care for older people often depict their work in negative terms, and they oft

Charting the human lung with inhaled nanoparticles : Development of AiDA - a new diagnostic technique for respiratory disease

Changes to the smallest structures of the distal lung are often the first sign of severe respiratory disease, but to date methods to detect and quantify these changes are limited. Chronic obstructive pulmonary disease (COPD) is currently estimated to be the third most common cause of death worldwide, but is to a large extent under-diagnosed, especially at early stages. This thesis explores a new m

About Not Understanding the System : Ignorance as an Obstacle to a Meaningful Life in Sweden

This presentation builds on several ethnographic fieldworks (2011-2015) in southern Sweden on people who have Palestinian background as well as my on-going informal involvement with Palestinian networks. The field material includes about 35 qualitative interviews, numerous informal discussions and participant observations of political events (mostly demonstrations and lectures) and people’s daily This presentation builds on several ethnographic fieldworks (2011-2015) in southern Sweden on people who have Palestinian background as well as my on-going informal involvement with Palestinian networks. The field material includes about 35 qualitative interviews, numerous informal discussions and participant observations of political events (mostly demonstrations and lectures) and people’s daily

Using Optimal Mass Transport for Tracking and Interpolation of Toeplitz Covariance Matrices

In this work, we propose a novel method for interpolation and extrapolation of Toeplitz structured covariance matrices. By considering a spectral representation of Toeplitz matrices, we use an optimal mass transport problem in the spectral domain in order to define a notion of distance between such matrices. The obtained optimal transport plan naturally induces a way of interpolating, as well as e

From the mid-Ordovician into the Late Silurian : Changes in the micrometeorite flux after the L chondrite parent breakup

We present the first reconstruction of the micrometeorite flux to Earth in the Silurian Period. We searched 321 kg of condensed, marine limestone from the Late Silurian Cellon section, southern Austria, for refractory chrome-spinel grains from micrometeorites that fell on the ancient sea floor. A total of 155 extraterrestrial spinel grains (10 grains >63 μm, and 145 in the 32-63 μm fraction) were

Effects of Age, BMI, anxiety and stress on the parameters of a stochastic model for heart rate variability including respiratory information

Recent studies have focused on investigating different factors that may affect heart rate variability (HRV), pointing especially to the effects of age, gender and stress level. Other findings raise the importance of considering the respiratory frequency in the analysis of HRV signals. In this study, we evaluate the effect of several covariates on the parameters of a stochastic model for HRV. The d

Class discriminator-based EMG classification approach for detection of neuromuscular diseases using discriminator-dependent decision rule (D3R) approach

Classification of EMG signals is essential for diagnosis of motor neuron diseases like neuropathy and myopathy. Although a number of strategies have been implemented for classification, none of them are efficient enough to be implemented in clinical environment. In the present study, we use ensemble approach of support vector machines for classification of three classes (normal, myopathic and neur

Sex differences in local adaptation : what can we learn from reciprocal transplant experiments?

Local adaptation is of fundamental interest to evolutionary biologists. Traditionally, local adaptation has been studied using reciprocal transplant experiments to quantify fitness differences between residents and immigrants in pairwise transplants between study populations. Previous studies have detected local adaptation in some cases, but others have shown lack of adaptation or even maladaptati