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Biomarkers of microvascular endothelial dysfunction predict incident dementia : a population-based prospective study
BACKGROUND: Cerebral endothelial dysfunction occurs in a spectrum of neurodegenerative diseases. Whether biomarkers of microvascular endothelial dysfunction can predict dementia is largely unknown. We explored the longitudinal association of midregional pro-atrial natriuretic peptide (MR-proANP), C-terminal endothelin-1 (CT-proET-1) and midregional proadrenomedullin (MR-proADM) with dementia and s
Action Recognition Online with Hierarchical Self-Organizing Maps
We present a hierarchical self-organizing map based system for online recognition of human actions. We have made a first evaluation of our system by training it on two different sets of recorded human actions, one set containing manner actions and one set containing result actions, and then tested it by letting a human performer carry out the actions online in real time in front of the system’s 3D
Defensive coping and essential amino acid markers as possible predictors for structural vascular disease in an African and Caucasian male cohort : The SABPA study
Defensive coping (DefS), oxidative stress, inflammation, and related amino acids (phenylalanine [Phe] and tyrosine [Tyr]) have been implicated in cardiovascular disease. This study assessed whether inflammation, oxidative stress, changes in essential amino acids, and altered coping strategies are correlated with subclinical vascular changes in African (n = 82) and Caucasian (n = 100) men from the
Postprandial Levels of Branch Chained and Aromatic Amino Acids Associate with Fasting Glycaemia
High fasting plasma concentrations of isoleucine, phenylalanine, and tyrosine have been associated with increased risk of hyperglycaemia and incidence of type 2 diabetes. Whether these associations are diet or metabolism driven is unknown. We examined how the dietary protein source affects the postprandial circulating profile of these three diabetes associated amino acids (DMAAs) and tested whethe
Open innovation using open source tools : a case study at Sony Mobile
Despite growing interest of Open Innovation (OI) in Software Engineering (SE), little is known about what triggers software organizations to adopt it and how this affects SE practices. OI can be realized in numerous of ways, including Open Source Software (OSS) involvement. Outcomes from OI are not restricted to product innovation but also include process innovation, e.g. improved SE practices and
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Early Communication skills: important in screening for language impairment and neuropsychiatric disorders
The relationship between language skills and interactional skills in children with language impairment
This study investigates interaction in dialogues between children with language impairment (LI) and peers of different ages and at two different times, taking into account the language skills of the children with LI. The hypotheses tested were that dialogues between more mature children are more coherent and that the degree of language problems of the child with LI is not directly associated with
Bovine β-casein has a polydisperse distribution of equilibrium micelles
β-casein, a self-associating protein, has been extensively studied over the years, and it is a molecule that is of academic, industrial, and clinical relevance. Therefore it is of interest to understand the structural and conformational properties of the assemblies, also denoted micelles. Here we show that β-casein possess a polydisperse distribution of equilibrium micelles, which has, to the auth
Changes in proteins, physical stability and structure in directly heated UHT milk during storage at different temperatures
Changes occurring in directly heated UHT milk were studied during storage at 5, 22, 30 and 40 °C. Industrially produced UHT milk samples were analysed for changes in enzymatic activity, protein modification, destabilisation of casein micelles and relocation of milk proteins in relation to sedimentation and gel formation. Sedimentation occurred at all temperatures, and the protein composition of th
Agricultural management practices influence AMF diversity and community composition with cascading effects on plant productivity
Understanding the effects of different agricultural practices on the mycorrhizal symbiosis is important for agricultural production and the sustainable use of soil. We investigated the composition and diversity of arbuscular mycorrhizal fungi (AMF) in soils from fields under different agricultural practices (conventional and organic cereal fields, leys and permanent pastures) in southern Sweden. T
Fabrication of user-friendly and biomimetic 1,1′-carbonyldiimidazole cross-linked gelatin/agar microfluidic devices
We have developed a straightforward technique for fabricating user-friendly and biomimetic microfluidic devices out of a gelatin/agar gel cross-linked with 1,1′-carbonyldiimidazole. The fabrication procedure requires only inexpensive starting materials such as glass capillaries and wires to mold 3D cylindrical channels into the gel with the possibility of achieving channel diameters of 375 μm and
Testing the performances of automated identification of bat echolocation calls : A request for prudence
Echolocating bats are surveyed and studied acoustically with bat detectors routinely and worldwide, yet identification of species from calls often remains ambiguous or impossible due to intraspecific call variation and/or interspecific overlap in call design. To overcome such difficulties and to reduce workload, automated classifiers of echolocation calls have become popular, but their performance
Computational Methods for Reconstruction: Signed Distance Functions, Low Rank Models and Depth Sensors
Local heat transfer in subcooled flow boiling in a vertical mini-gap channel
An experimental study of subcooled flow boiling in a high-aspect-ratio, one-sided heating rectangular mini-gap channel was conducted using deionized water. The local heat transfer coefficient, onset of nucleate boiling (ONB), and flow pattern of subcooled boiling were investigated. The influence of heat flux and mass flux were studied with the aid of a high-speed camera. The bubbles were generated
Ecotoxicological assessment of propiconazole using soil bacterial and fungal growth assays
Effects of the fungicide propiconazole on soil microorganisms were tested using [3H] leucine incorporation and [14C] acetate in ergosterol incorporation to measure bacterial and fungal growth inhibition, respectively. Growth was compared to basal respiration (BR) and substrate-induced respiration (SIR) in soil microcosms established according to the OECD 217 guideline. Fungal growth was most sensi
On resilient control of dynamical flow networks
Resilience has become a key aspect in the design of contemporary infrastructure networks. This comes as a result of ever-increasing loads, limited physical capacity, and fast-growing levels of interconnectedness and complexity due to the recent technological advancements. The problem has motivated a considerable amount of research within the last few years, particularly focused on the dynamical as
The dissipation rate of turbulent kinetic energy and its relation to pumping power in inline rotor-stator mixers
The theoretical understanding of inline rotor-stator mixer (RSM) efficiency, described in terms of the dissipation rate of turbulent kinetic energy as a function of mixer design and operation, is still poor. As opposed to the correlations for shaft power draw, where a substantial amount of experimental support for the suggested correlations exists, the previously suggested correlations for the dis
