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In 2006 the European Commission introduced the concept of "Pre-Commercial Procurement" as an instrument to promote innovation and to mitigate grand challenges. One of the main motives for the support of Pre-Commercial Procurement schemes was to use public needs as a driver for innovation. This concept was also introduced as a response to the need to reinforce the innovation capabilities of the EU,
The electric quadrupole (E2) and magnetic octupole (M3) ground-state transitions in Ni-like W46+ have been measured using high-resolution crystal spectroscopy at the LLNL electron-beam ion trap facility. The lines fall in the soft x-ray region near 7.93 angstrom and were originally observed as an unresolved feature in tokamak plasmas. Using flat ammonium dihydrogen phosphate and quartz crystals, t
Objective: The authors sought to clarify the sources of parent-offspring resemblance for drug abuse, alcohol use disorders, and criminal behavior, using a novel genetic-epidemiological design. Method: Using national registries, the authors identified rates of drug abuse, alcohol use disorders, and criminal behavior in 41,360 Swedish individuals born between 1960 and 1990 and raised in triparental
To investigate whether threat to fixation (TTF) at diagnosis increases the risk of central vision loss and glaucoma blindness.
BACKGROUND: The current model of care for individuals with breast cancer focuses on treatment of the disease, followed by ongoing surveillance to detect recurrence. This approach lacks attention to patients' physical and functional well-being. Breast cancer treatment sequelae can lead to physical impairments and functional limitations. Common impairments include pain, fatigue, upper-extremity dy
Extensive published evidence supports the use of subcutaneously-administered apomorphine as an effective therapy for Parkinson's disease (PD) but to date no consensus recommendations have been available to guide healthcare professionals in the optimal application of apomorphine therapy in clinical practice. This document outlines best-practice recommendations for selecting appropriate candidates f
A detailed investigation of the decomposition reactions and decay in the hydrogen storage capacity during repeated hydrogen release and uptake cycles for the reactive composite LiBH4-Al (2:3) is presented. Furthermore, the influence of a titanium boride, TiB2, additive is investigated. The study combines information from multiple techniques: in situ synchrotron radiation powder X-ray diffraction,
Neurodegenerative diseases can cause dysfunction of neural structures involved in judgment, executive function, emotional processing, sexual behavior, violence, and self-awareness. Such dysfunctions can lead to antisocial and criminal behavior that appears for the first time in the adult or middle-aged individual or even later in life.
Software breast phantoms are increasingly seeing use in preclinical validation of breast image acquisition systems and image analysis methods. Phantom realism has been proven sufficient for numerous specific validation tasks. A challenge is the generation of suitably realistic small-scale breast structures that could further improve the quality of phantom images. Power law noise follows the noise
A monatomic layer of graphite (MG or graphene) adsorbed on the (111) faces of transition metals Pt, Ir, and Ni, has been employed for controlling the atomic hydrogen adsorption site selectivity and the amount of hydrogen adsorbed upon saturation. The variations in the graphene-metal chemical bonding caused by hydrogenation and the values of saturated hydrogen coverage have been studied by X-ray ph
This paper presents an energy-efficient sorted QR decomposition (SQRD) processor for 3GPP LTE-Advanced (LTE-A) systems. The processor adopts a hybrid decomposition scheme to reduce computational complexity and provides a wide-range of performance complexity trade-offs. Based on the energy distribution of spatial channels, it switches between the brute-force SQRD and a low-complexity group-sort QR-
Islands of innovation as magnetic centres of star scientists? Empirical evidence on spatial concentration and mobility patterns, Regional Studies. Drawing on the results of a survey of 720 ‘star scientists’, this paper seeks to analyse the role of islands of innovation in the United States and Europe in providing educational and employment opportunities for such scientists and in attracting intern
PURPOSE A binational, population-based treatment protocol was established to prospectively treat and follow patients with seminomatous testicular cancer. The aim was to standardize care for all patients with seminoma to further improve the good results expected for this disease. PATIENTS AND METHODS From 2000 to 2006, a total of 1,384 Norwegian and Swedish patients were included in the study. Trea
Abstract Patients' satisfaction is an important outcome measure in reconstructive surgery and quality assurance is today central in the clinical practice. The aim of this study was to evaluate the patients' satisfaction with the process and final result after reconstruction for congenital microtia. A questionnaire was designed and sent to 78 patients who had undergone unilateral ear reconstruction
In the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) trial, combined ezetimibe (10 mg) and simvastatin (40 mg) decreased low-density lipoprotein cholesterol levels by 50% and ischemic cardiovascular event (ICE) risk by 22% compared to placebo. A larger decrease in ICE risk might have been expected for the degree of lipid-lowering observed. This analysis investigated relations between changes
Conditional cash transfers (CCTs) are often being promoted for their simultaneous advantages of short-term income protection and long-term human capital investments. Yet, existing evaluations have largely failed to test the underlying programme theory, and few empirical case studies have explored inherent contradictions and ambiguous consequences of this hybrid approach. To further understand the
Prior studies, utilizing interview-based assessments, suggest that most of the genetic risk factors for drug abuse (DA) are non-specific with a minority acting specifically on risk for abuse of particular psychoactive substance classes. We seek to replicate these findings using objective national registry data.
