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Hjalmarsson (2010) considers an OLS-based estimator of predictive panel regressions that is argued to be mixed normal under very general conditions. In a recent paper, Westerlund et al. (2016) show that while consistent, the estimator is generally not mixed normal, which invalidates standard normal and chi-squared inference. The purpose of the present paper is to study the consequences of this the
The difficulty of predicting returns has recently motivated researchers to start looking for tests that are either more powerful or robust to more features of the data. Unfortunately, the way that these tests work typically involves trading robustness for power or vice versa. The current paper takes this as its starting point to develop a new panel-based approach to predictability that is both rob
n order to protect their food from competitors, ball-rolling dung beetles detach a piece of dung from a pile, shape it into a ball, and roll it away along a straight path [1]. They appear to rely exclusively on celestial compass cues to maintain their bearing [2, 3, 4, 5, 6, 7 and 8], but the mechanism that enables them to use these cues for orientation remains unknown. Here, we describe the orien
Asteroid 4 Vesta is the only currently identified asteroid for which we possess samples in the form of meteorites. These meteorites revealed us that Vesta is a differentiated body and that its differentiation produced a relatively thin basaltic crust that survived intact over its entire collisional history. The survival of the vestan basaltic crust has long been identified as a pivotal constraint
Introduction: The gastro-intestinal hormone glucose-dependent insulinotropic polypeptide (GIP) potentiates glucose-induced insulin secretion, with bone anabolic effects through GIP receptor (GIPR) in animal models. We explore its potential in humans by analyzing association between polymorphisms (SNPs) in the GIP and GIPR genes with bone phenotypes in young and elderly women. Methods: Association
The National Environmental Objectives (NEOs) adopted by Swedish Parliament in 2001 and proclaimining that major environmental problems should be solved within a generation are often portrayed as good practice of a concrete yet visionary sustainability strategy. In this paper we summarize one and a half decade of the NEOs' experience for the international audience. The NEOs were based on an eclecti
Reduction in traffic-induced ground vibrations by the use of barriers is investigated. The traffic load characteristics were measured for motorway traffic. The effects of parameters on various types of barriers were examined by the use of a finite element model that was calibrated to green-field measurements. The model involved a layered soil and bedrock. The depth of a trench and the elastic modu
The concrete discs with water-cement ratios 0.4 and 0.7 were preconditioned at their early age by drying at 50`C for 2 to 4 days, followed by storage in a Laboratory atmosphere till an age of 28 or S6 days. The moisture distributions in the specimens were determined by measuring relative humidity and capillary saturation degree, and the air permeability was determined according to the Cembureau me
‘Some textbooks treat PR as though it is a branch of moral philosophy. Such an approach leaves most PR practitioners bemused and is of limited practical use.’ (Morris & Goldsworthy 2012, 41) The grand narrative of the public relations-field in the 20th and 21st century arguably is that of professionalization. The story presented by professional associations and academics alike tells of a pract
This dissertation examines contemporary politics targeting people with intellectual disabilities. Since this group first emerged, under labels such as ‘idiocy’ and ‘mental deficiency’, around the turn of the 20th century, its members have been seen as lacking the capacities necessary for citizenship and full societal belonging. For the last forty years, however, liberal democracies and internation
Noncoding RNAs control critical cellular processes, although their contribution to disease remains largely unexplored. Dyskerin associates with hundreds of H/ACA small RNAs to generate a multitude of functionally distinct ribonucleoproteins (RNPs). The DKC1 gene, encoding dyskerin, is mutated in the multisystem disorder X-linked dyskeratosis congenita (X-DC). A central question is whether DKC1 mut
Objective To determine the relative risks of prostate cancer incidence, metastasis, and mortality associated with screening by serum prostate specific antigen (PSA) levels at age 60. Design Population based cohort study. Setting General male population of Sweden taking part in a screening trial in Gothenburg or participating in a cardiovascular study, the Malmo Preventive Project. Participants The
How pseudouridylation (Ψ), the most common and evolutionarily conserved modification of rRNA, regulates ribosome activity is poorly understood. Medically, Ψ is important because the rRNA Ψ synthase, DKC1, is mutated in X-linked dyskeratosis congenita (X-DC) and Hoyeraal-Hreidarsson (HH) syndrome. Here, we characterize ribosomes isolated from a yeast strain in which Cbf5p, the yeast homolog of DKC1
