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The Rieger syndrome, an autosomal dominant disorder involving ocular, dental, and umbilical defects is caused bymutations in PITX2, a Bicoid type homeobox protein. Moreover, Pitx2 is involved in the Nodal/Sonic hedgehogpathway that determines left/right polarity. Mouse Pitx2 mRNA is expressed in eye, tooth and umbilicus consistent withthe human Riegers phenotype. It is also asymmetrically expresse
This issue of Journal of Scandinavian Cinema features a diverse range of articles covering topics from early silent cinema to contemporary genre filmmaking. Highlights include discussions of digital restoration, cinematic influence, Sámi culture, horror in children’s cinema and film literacy. The issue also reviews new research on Carl Th. Dreyer that emphasizes the emotional aspects of his films.
Background: Pediatric atopic dermatitis (AD) is a common chronic disease. For assessing treatment outcomes, the concept of controlled and uncontrolled AD has been introduced. Objectives: The aim of the study was to estimate healthcare resource use in terms of visits, treatments and costs in children with controlled and uncontrolled AD. Materials & Methods: The study utilised administrative dat
This entry reflects on the meaning and significance of playful work in contemporary organizations. In recent years, playful work has become a prominent managerial technique to combat employee disengagement and low morale in organizations. This trend has its roots in positive psychology, especially Csikszentmihalyi’s concept of flow and Deci and Ryan’s self-determination theory. Developments such a
What future aspirations have informed the incentives for producing children's literature in Muslim minority communities? What social dynamics and theological debates have accompanied its visions of Islamic futures? What narrative tropes, visual-aesthetics norms and literary genres has it appropriated, while maturing into an innovative religious-pedagogic-literary expression? Probing such questions
BACKGROUND: Acute myeloid leukemia (AML) is an aggressive hematological neoplasm. Little improvement in survival rates has been achieved over the past few decades. Necroptosis has relationship with certain types of malignancies outcomes. Here, we evaluated the diagnostic ability, prognostic capacity of necroptosis-related genes (NRGs) and the effect of their copy number variations (CNVs) in AML.ME
Intracellular delivery is crucial in biological and medical studies. Although many molecular tools have been created for cell-based gene therapies, it remains challenging to introduce external molecules into cells. As one of the most popular non-viral transfection methods, electroporation induces transient pores in the cell membrane by applying an external electric field. Unsatisfactory transfecti
Quark spin effects in e+e- annihilation to pseudoscalar and vector mesons are implemented for the first time in the pythia Monte Carlo event generator. The spin-dependent fragmentation of the string stretched between the produced quark-antiquark pair with correlated spin states is described by the string+P30 model implemented in the string fragmentation routine of pythia by using the StringSpinner
Few studies have examined the association of various types of Fe with colorectal cancer risk. The aim of this study was to investigate different forms and sources of Fe in relation to colorectal cancer risk in a Chinese population. A total of 2138 patients with colorectal cancer and 2144 sex- and age-matched (5-year interval) controls were recruited from July 2010 to November 2017. Dietary informa
This cross-over experimental study aimed to examine the effects of filled chocolate consumption on blood glucose, insulin and ghrelin levels in 20 volunteers. After a one-week run-in period, study participants consumed two chocolate-based products, the tested biscuit or water for 21 days as a morning snack. After a two-week wash-out period, participants consumed another tested food for another 21
Objectives: Decision-analytic models assessing the value of emerging Alzheimer's disease (AD) treatments are challenged by limited evidence on short-term trial outcomes and uncertainty in extrapolating long-term patient-relevant outcomes. To improve understanding and foster transparency and credibility in modeling methods, we cross-compared AD decision models in a hypothetical context of disease-m
This study aimed to explore the effect of dietary magnesium intake on breast cancer risk both directly and indirectly via its effect on inflammatory markers C-reactive protein (CRP) and interleukin-6 (IL-6). This case-control study recruited 1050 case patients and 1229 control subjects. Inflammatory marker levels of 322 cases and 322 controls, randomly selected, were measured using ELISA, and data
This article examines the narratives associated with the “Shekou Model” in China’s development of the Hambantota International Port in Sri Lanka. Through a dual narrative analysis and policy evaluation approach utilizing official Chinese and Sri Lankan statements, it examines the motivations of the Chinese Communist Party and the China Merchants Group in “selling” the Shekou Model and how Sri Lank
A carbohydrate-rich diet results in hyperglycaemia and hyperinsulinaemia; it may further induce the carcinogenesis of colorectal cancer. However, epidemiological evidence among Chinese population is quite limited. The aim of this study was to investigate total carbohydrate, non-fibre carbohydrate, total fibre, starch, dietary glycaemic index (GI) and glycaemic load (GL) in relation to colorectal c
The effects of dietary vitamin D, Ca and dairy products intakes on colorectal cancer risk remain controversial. The present study investigated the association between these dietary intakes and the risk of colorectal cancer in Guangdong, China. From July 2010 to December 2018, 2380 patients with colorectal cancer and 2389 sex- and age-matched controls were recruited. Dietary intake data were collec
Anti-tumor effect of dietary flavonoids has been sustained by laboratory experiments, but epidemiological studies with breast cancer risk remained inconsistent and insufficient. This study aimed to investigate the associations between total and subclasses of flavonoid and breast cancer risk among Chinese population. This case-control study recruited 1522 eligible breast cancer cases and 1547 frequ
This chapter contextualizes and discusses the Buddhist approach taken by Ranil Wickremesinghe (born 1949), a prominent political figure who has served as Prime Minister of Sri Lanka on six occasions and who held the office of the ninth President until September 2024. It analyses Wickremesinghe’s political career and his ability to navigate the complex interplay between Sinhalese Buddhist ethno-rel
....men inte heller ett neutralt verktyg för offentlig förvaltning. Via en teknikhistorisk återblick diskuterar Stefan Larsson och Ellinor Blom Lussi aspekter av hur ny teknik, här med fokus på AI, påverkar individer, professioner och organisationer. Med denna introducerande artikel till temat digitalisering pekar de dels på några av de väldigt löftesrika tekniktrender som är kopplade till automat
