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Adolescents living with HIV are at higher risk of death and loss to follow up from care: Analysis of cohort data from eight health facilities in Ethiopia.

BACKGROUND:There are limited data on the treatment outcomes of adolescents living with HIV. Our objective was to compare mortality and loss to follow up (LTFU) rates between adolescent and younger age groups at enrollment in care.METHODS:This was a retrospective cohort study carried out in eight health facilities in two regions of Ethiopia. Adolescents (age 10-14 and 15-19 year) and children (age BackgroundThere are limited data on the treatment outcomes of adolescents living with HIV. Our objective was to compare mortality and loss to follow up (LTFU) rates between adolescent and younger age groups at enrollment in care.MethodsThis was a retrospective cohort study carried out in eight health facilities in two regions of Ethiopia. Adolescents (age 10–14 and 15–19 year) and children (age 0–

Problem gambling, associations with comorbid health conditions, substance use, and behavioural addictions : Opportunities for pathways to treatment

Background Problem gambling is a public health issue and its comorbidity with other health conditions may provide an opportunity for screening in healthcare settings; however, a high level of uncertainty and a lack of research in the field remains. The objective of this study is to investigate potential associations between problem gambling and numerous other health conditions, including substance

Large-Scale Retrieval of Coloured Dissolved Organic Matter in Northern Lakes Using Sentinel-2 Data

Owing to the significant societal value of inland water resources, there is a need for cost-effective monitoring of water quality on large scales. We tested the suitability of the recently launched Sentinel-2A to monitor a key water quality parameter, coloured dissolved organic matter (CDOM), in various types of lakes in northern Sweden. Values of a(420)CDOM (CDOM absorption at 420 nm wavelength)

Convergence in the p-Contest

We study asymptotic properties of the following Markov system of N≥3 points in [0, 1]. At each time step, the point farthest from the current centre of mass, multiplied by a constant p>0, is removed and replaced by an independent ζ-distributed point; the problem, inspired by variants of the Bak–Sneppen model of evolution and called a p-contest, was posed in Grinfeld et al. (J Stat Phys 146, 378–40

Handledare på dubbla stolar

En studierektor för doktorander bör inte samtidigt vara handledare eller biträdande handledare. Intressekonflikter kan uppstå. En doktorand kan hamna i en onödig och svår valsituation.

Von Willebrand factor alloantibodies in type 3 von Willebrand disease

The development of neutralizing antibodies is a rare complication of von Willebrand disease treatment. In major surgical procedures for severe forms of the disease, the recognition of ineffective therapy and alternative treatment protocols are lifesaving. We report the case of a 6-year-old girl with type 3 von Willebrand disease in whom inhibitors were sought due to ineffective haemostasis togethe

Early repolarization pattern on ECG recorded before the acute coronary event does not predict ventricular fibrillation during ST-elevation myocardial infarction

Background: Generally considered benign, electrocardiographic (ECG) early repolarization (ER) pattern was claimed to be an indicator of increased susceptibility to ventricular arrhythmias during acute ischemia. Objective: The purpose of this study was to assess in a nonselected population whether ER pattern documented before ST-elevation myocardial infarction (STEMI) is associated with risk of hem

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk remain largely unknown. These regions were explored by combining association analysis with in silico genomic feature annotations. We defined 205 independent risk-associated signals with the set of credible causal variants in each one. In parallel, we used a Ba

Selfsimilar solutions for stress driven material dissolution : Advanced Fracture Mechanics for Life and Safety Assessments

During corrosive dissolution of metal ions from a body surface, an oxide compound isproduced. This compound forms a protective film that reduces the dissolution rate. When afraction of a millimetre depth is dissolved the dissolution rate become insignificant. However,repeated loading will damage the film with continued dissolution as a result. In connectionwith this a threshold strain is assumed tDuring corrosive dissolution of metal ions from a body surface, an oxide compound isproduced. This compound forms a protective film that reduces the dissolution rate. When afraction of a millimetre depth is dissolved the dissolution rate become insignificant. However,repeated loading will damage the film with continued dissolution as a result. In connectionwith this a threshold strain is assumed t

Implementation of the Swedish Guideline for Prevention of Mental ill-health at the Workplace : study protocol of a cluster randomized controlled trial, using multifaceted implementation strategies in schools

BACKGROUND: Given today's high prevalence of common mental disorders and related sick leave among teachers, an urgent need exists for a more systematic approach to the management of social and organizational risk factors within schools. In 2015, we launched the first Swedish occupational health guideline to support a structured prevention of these risks at the workplace. The existence of guideline

Genetic predisposition for multiple myeloma

Multiple myeloma (MM) is the second most common blood malignancy. Epidemiological family studies going back to the 1920s have provided evidence for familial aggregation, suggesting a subset of cases have an inherited genetic background. Recently, studies aimed at explaining this phenomenon have begun to provide direct evidence for genetic predisposition to MM. Genome-wide association studies have