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Recombinant adeno-associated virus (rAAV) has emerged as an attractive gene delivery vector platform to treat both rare and pervasive diseases. With more and more rAAV-based therapies entering late-stage clinical trials and commercialization, there is an increasing pressure on the rAAV manufacturing process to accelerate drug development, account for larger trials, and commercially provide high do

In July 2020, two Holocaust memorials disappeared from a Jewish cemetery in Stockholm where Holocaust survivors who died soon after coming to Sweden for medical treatment in 1945 are buried. Though it occurred in the midst of both the global #TakeItDown movement and the Swedish government’s plans to establish a Holocaust museum in Sweden, this removal garnered no media attention or public outcry.

For decades, extensive surfactant libraries have been developed to meet the requirements of downstream applications. However, achieving functional diversity has traditionally demanded a vast array of chemical motifs and synthetic pathways. Herein, a new approach for surfactant design based on structural isomerism is utilised to access a wide spectrum of functionalities. A library of C18-aliphatic

In this article I discuss whether viewing safety as a necessary condition for knowing entails that the truth-conditions for knowledge is context-sensitive. I argue that, while it is far from clear-cut, there is at least not a strict entailment between the positing of safety as necessary for knowledge and the context-sensitivity of knowledge, and so, that one can remain an invariantist about knowleIn this article I discuss whether viewing safety as a necessary condition for knowing entails that the truth-conditions for knowledge is context-sensitive. I argue that, while it is far from clear-cut, there is at least not a strict entailment between the positing of safety as necessary for knowledge and the context-sensitivity of knowledge, and so, that one can remain an invariantist about knowle

Background: Metastasis to lymph nodes is strongly associated with reduced survival in breast cancer patients. To increase the understanding on how lymph node metastasis impairs the local immune response in affected lymphnodes, we here studied spatial proteomic changes of critical lymph node immune populations in uninvolved lymph nodes (UnLN) and paired lymph nodes with metastases (LNM) from five b

Entrepreneurial initiatives aiming to transform organizations from the bottom up are often complicit with the power structures they seek to change, reproducing the old while trying to cultivate the new. To unleash the transformative potential of these initiatives, it is crucial to better understand how workers can productively reckon with complicity and how this reckoning drives the entrepreneuria

Cerebrospinal fluid (CSF) circulation is a complex process that is still not fully understood. Despite decades of research on CSF and its distinct functions, there still remain a number of open questions regarding the mechanisms that govern its circulation. The recently discovered glymphatic system, which is mostly active during sleep, clears the brain from extracellular metabolites and waste prod

The growth of III-V nanowires has attracted significant attention due to their superior electrical and optical properties, which are crucial for advanced optoelectronic devices such as lasers and photonic circuits. Since the 1960s, Au has beenextensively used as a catalyst for III-V nanowire growth, with substantial research conducted through both ex situ and in situ techniques. However, Au introd

At the core of this artistic research project is the idea that composing music can entail more than structuring sonic material; it may involve constructing the very space in which musical thoughts take shape. This space, the composable, is understood not as a fixed, pre-existing framework but as a space in flux—shaped by instruments, devices, spatial configurations, and performative gestures—where

This paper presents a methodology for estimation of physically interpretable building energy performance characteristics such as: heat loss coefficient, azimuth angle dependent solar gain, and diurnal periodicity in heat-demand. The models are demonstrated on a case-study with hourly observations of district-heating connected apartment buildings in Denmark. The weather model inputs are obtained fr

In 2015 the Rockefeller Foundation-Lancet Commission defined planetary health as built on an ecological model that integrates the material, biological, social, and cultural aspects of public health and accepts the complexity and non-linearity of the dynamics of natural systems. The zoonotic COVID-19 pandemic hastened this awaking to the symbiotic nature of planetary health politics (PHP), with the

According to Disney, “In Tomorrowland, the future is today!” In 2015 Brad Bird’s eco-science fiction film, Tomorrowland: A World Beyond, was released to coincide with the 60th anniversary of the opening of the futuristic theme park land. The film was described as a “a gorgeous, flawed utopia” but flopped at the box office. The Disneyfication of climate crisis for commercial purpose serves as a veh

For some time now, IR has been experiencing a narrative turn, with an increasing number of empirical analyses using the concept. However, its ontological, epistemological and methodological assumptions and implications are not always addressed. The panel aims to facilitate a conceptual debate on three sets of questions: Ontology: How does our understanding of the concept depend on the social theor

With increased focus on sustainable building materials and the growing popularity of uncoated wooden cladding, understanding consumer acceptance of aesthetic changes becomes crucial for sustainable architectural choices. This study investigated consumer acceptance of uncoated wooden cladding in Norway, Sweden, and Germany, focusing on personality traits and perceptions. Using an online survey with

Cubosomes are non-lamellar lipid nanoparticles that have drawn a significant attention in the field of nanomedicine due to their tunable properties. However, the formation of vesicles during the preparation of cubosomes, and the presence of mixed bicontinuous cubic phases, may lead to artifacts and lack of correlation between the physico-chemical and biological characterization. In this work, we h